CF is a genetic disease, meaning that a person does not “catch it”, it is inherited in the genes passed down to the person. Cystic fibrosis lasts with the patient for their whole life. This makes it a chronic disease, not communicable (9). All symptoms of CF are caused by a mutation to the single chromosome 7. This particular gene is responsible for the building of the protein called the cystic fibrosis trans membrane conductance regulator (CFTR). Normally, the gene regulates the passage of chloride ions in and out of the cell, but when mutated as in the case of CF patients the chloride ions cannot move throughout the cell membrane because the CFTR does not open. In about three- quarter of CF cases the CFTR is not just broken, ...
... middle of paper ...
...ed is the short life expectancy, however the advanced treatments that have been developed have assisted in prolonging the life expectancy of CF patients. In 1940 the majority of children with CF did not live until their first birthday. By 1969 most patients with CF lived until their 14th birthday, and in 1996 the average life expectancy of a person with CF is 39 years old, this figure is constantly improving (2).
Perhaps the hardest thing to deal with is the fact that there is nothing that can be done to prevent it from happening, it is simply in the DNA makeup of the individual. Cystic fibrosis is a challenging disease to live with but the treatments that have been developed are forever improving the quality of life of those diagnosed with the fatal disease. Maybe with the advancements in medicine, one day there will be a cure, but all that can be done is hope.
Need Writing Help?
Get feedback on grammar, clarity, concision and logic instantly.Check your paper »
- Cystic Fibrosis Cystic Fibrosis is a genetic disease that affects many people today. It takes over a person’s whole life to survive this disease. To survive, people who suffer with Cystic Fibrosis need constant care of this disease. Cystic fibrosis is disorder that is inherited and causes severe damage to the lungs and digestive system. Cystic fibrosis changes the cells that make mucus, sweat and digestive juices. These fluids that are secreted are normally thin and slippery. A defective gene causes the secretions to become thick and sticky.... [tags: Cystic fibrosis, Genetics, Digestion, Pneumonia]
809 words (2.3 pages)
- The effects of cystic fibrosis can be broken down to a micro-perspective investigation in both the genotype, the encoding of the DNA, and the phenotype, the expression of DNA to trait. A precursor to the expression of cystic fibrosis, is through the inheritability pattern of cystic fibrosis from both parents. Cystic fibrosis is an autosomal recessive disease, meaning in the DNA of each parent, each had one copy of these recessive trait which is not expressed through them. However, with both parents being carriers, the offspring has a 25% chance of inheriting cystic fibrosis, a 25% chance of inheriting non-mutated genes and a 50% chance of being a carrier of the cystic fibrosis gene (Mayer-Ha... [tags: Mutation, DNA, Gene, Cystic fibrosis]
992 words (2.8 pages)
- Cystic Fibrosis Introduction Cystic fibrosis (CF) is an inherited chronic disease that must be carried by both parents in order to for the person to suffer from it. When two parents who are carriers have a child there is a 25 percent chance of having a child with CF and when one parents has CF and one parent is a carrier, there is a 50 percent chance of having a child with CF This disease affects organs such as the liver, lungs, pancreas, and intestines. This disease disrupts the body’s salt balance leaving too little salt and water on the outside of cells which makes the thin mucus that protects the linings of the airways, digestive system, reproductive system, and other organs and tissues... [tags: Cystic fibrosis, Pulmonology, Asthma]
1312 words (3.7 pages)
- Cystic fibrosis is a genetically inherited disease due to a mutation in the CFTR gene. This disease causes life changing health complications that affect many organs within the human body. There is always ongoing research for this disease to discover better treatment options that are more effective and possibly find a cure to reverse the mutated gene. The Cystic fibrosis transmembrane conductance regulator gene (CFTR) is responsible for providing the instructions to help make the protein that produces mucus in the body.... [tags: Cystic fibrosis, Genetics, Mutation, Asthma]
1836 words (5.2 pages)
- Cystic Fibrosis A passage dated as far back as 1857 in the ‘Almanac of Children’s Songs and Games from Switzerland’ cautioned that ‘the child will soon die whose forehead tastes salty when kissed’. This theory was proven by Paul di Sant’Agnese in 1953 when he discovered that the salt content of victims of cystic fibrosis sweat was significantly high. With the sweat test being created out of this discovery, the invasive methods of diagnosing people with cystic fibrosis has been replaced and is continuously used as the cornerstone for diagnosing this disease.... [tags: symptoms, chromosome, hereditory disorder]
780 words (2.2 pages)
- Cystic Fibrosis and Gene Therapy The average life span of a person with Cystic Fibrosis is 25-30 years of age. Although the more traditional treatments of this disease are adequate, is there something else that could be even better. Gene therapy is fast becoming one of the more studied aspects of genetics today. Let's take a look at some details of Cystic Fibrosis and gene therapy. Technical Aspects Cystic Fibrosis (CF) is the most common fatal genetic disease in the United States today. CF is an autosomal recessive disease that occurs approximately one out of 3,300 live births (Cystic Fibrosis Foundation, 1998).... [tags: Science Genetics Biology Papers]
2209 words (6.3 pages)
- Cystic fibrosis is a chronic, inherited, life threatening disease that affects organs in the body, because of sticky and thick mucus buildup on organs. The organs that are affected are the liver, lungs, pancreas, and intestine, which does damage to the respiratory, digestive and reproductive systems (Crosta). Cystic fibrosis is caused by a mutation in a gene called cystic fibrosis trans-membrane regulator, also called CFTR, which has an important function of creating sweat, mucus and digestive juices (Crostra).... [tags: chronic disease, transporter gene, CFTR]
1071 words (3.1 pages)
- Cystic Fibrosis Results from Mutations in the genes encoding the cystic fibrosis trans membrane conductance regulator. This protein product is a traffic ATPase and C1 channel which localizes to the apical membrane of airway Epithelial. Breaking it down, Cystic Fibrosis is the most deadly common inherited disease affecting Caucasians in the United States. Cystic Fibrosis is a disorder that causes a thick and very sticky mucus to build up in the lungs and digestive tracks. Normally mucus in the lungs trap germs, which are then cleared out of the lungs, but in Cystic Fibrosis the mucus traps the germs in the lungs.... [tags: Disease ]
968 words (2.8 pages)
- CYSTIC FIBROSIS ONE OUT OF EVERY 2,500 BIRTHS IN THE UNITED STATES WILL BE DIAGNOSED WITH CYSTIC FIBROSIS. THIS FACT MAKES CYSTIC FIBROSIS ONE OF THE MOST COMMON GENETIC DISEASES IN THE NATION. ABOUT 30,000 AMERICANS HAVE THE DISEASE, BUT EVEN THOUGH CYSTIC FIBROSIS IS THE NATIONS MOST COMMON GENETIC DISEASE THE MAJORITY OF AMERICANS KNOW LITTLE ABOUT IT. CYSTIC FIBROSIS IS RELATIVELY COMMON IN CALCASTION PEOPLE BUT RARE IN AFRICAN-AMERICAN. THE DISEASE IS VERY UNCOMMON IN MONGOLIANS. FIVE PERCENT OF THE POPULATION IN THE UNITED STATES ARE CARRIERS OF THE GENETIC DISEASE.... [tags: essays research papers]
503 words (1.4 pages)
- CF is caused by an inherited recessive genetic defect that is most prevalent in the white population. About 1 in 23 people in the United States carry at least one defective gene, making it the most common genetic defect of its severity. CF patients suffer from chronic lung problems and digestive disorders caused by a cellular defect in the transport of chloride ion. The problem in chloride handling results in loss of chloride in sweat which, in fact, is the basis for the clinical diagnosis of CF.... [tags: Biology Genetic Defect]
3953 words (11.3 pages)