Sickle cell anemia is an inherited, lifelong, blood disorder disease, which is passed down through families. It is described as “sickle-shaped” for the strange appearance of the red blood cells (RBC). The red blood cells, which are normally shaped like a discs, takes on a sickle or crescent shape, therefore called sickle-shaped. Sickle cells have irregular hemoglobin, called sickle hemoglobin or hemoglobin S. Sickle hemoglobin is what causes the cells to develop a sickle, or crescent shape. This inherited blood disorder is one of the different types of anemia; the condition in which your blood has lower RBC’s than normal. You cannot catch this disease, for the person must be born with it by inheriting two genes for sickle hemoglobin—one from each parent. Unfortunately, there is no cure for the disease, however, treatments to improve the anemia and lower problems, can help with the symptoms and difficulties of this disease in both children and adults. There are now improved treatments and care that helps people who have sickle cell anemia live longer. Sickle cell disease (SCD) was first described in 1910 (Frenette & Atweh, 2007). SCD has existed in Africa for at least five thousand years and has been known by many different names in many different tribal languages; although, it was actually discovered in the United States. Walter Clement Noel, from the island of Grenada, was a dental student that was studying in Chicago. He complained about complications like pain, and symptoms of anemia, to search for answers he confided in Dr. James B. Herrick. Dr. Herrick was actually a cardiologist and was not interested in his case, so he was redirected to another doctor. This doctor named Dr. Ernest Irons, examined Mr. Noel and discovered ho... ... middle of paper ... ...ies, new concepts, and future promise. J Clin Invest, 117, 850–858. Retrieved on March 4, 2014 from http://www.jci.org/articles/view/30920 Sickle cell anemia. (2012). In Mosby's dictionary of medicine, nursing, & health professions. Retrieved from http://login.southuniversity.libproxy.edmc.edu/login?qurl=http%3A%2F%2Fliterati.credoreference.com.southuniversity.libproxy.edmc.edu%2Fcontent%2Fentry%2Fehsmosbymed%2Fsickle_cell_anemia%2F0 Sickle cell anemia. (2011). In The American Heritage Science Dictionary. Retrieved from http://login.southuniversity.libproxy.edmc.edu/login?qurl=http%3A%2F%2Fliterati.credoreference.com.southuniversity.libproxy.edmc.edu%2Fcontent%2Fentry%2Fhmsciencedict%2Fsickle_cell_anemia%2F0 What Is Sickle Cell Anemia. (2012). National Institutes of Health. Retrieved on March 4, 2014 From http://www.nhlbi.nih.gov/health/health-topics/topics/sca/
Sickle Cell Anemia is an autosomal recessive disorder, which increases blood thickness hence affects the smooth flow of blood. This causes by the destruction of red cells where the normal shape of red cell become a stiff sickle shape. As a result, sufficient oxygen does not reach the vital organs. A vaso-occlusive crisis arises from hindrance of blood circulation by sickled blood cells. It is characterized by sturdy pains and in some cases; it may cause permanent organ damage. This paper seeks to formulate a nursing diagnosis, as well as a plan of care that includes nursing interventions and the methods to be used to evaluate whether the interventions are successful (American Sickle Cell Anemia Association).
Sickle cell disease is a group of disorders that affects the blood, specifically, a molecule called hemoglobin in red blood cells (“sickle cell disease”, 2016). Hemoglobin is a molecule that facilitates the delivery of oxygen throughout the body (“sickle cell disease”, 2016). A mutant form of the hemoglobin molecule causes red blood cells to become crescent shaped or “sickled shaped” (Lonergan et. al. 2001). This distorted shape of red blood cells causes rigidity of the blood cells and vaso-occulusion (or the blood vessels to become clogged) (Rees et.al., 2010). This often leads to a low number of red blood cells (anemia), repeated infections and episodes of pain that are periodic (“Sickle cell disease”, 2016). Although sickle cell disease
What is Sickle cell disease? Sickle cell affects a disease; that disease is called which affects the hemoglobin when the red blood cells that send oxygen through the body are killed off and weakened. Sickle cells can be found in every 1 and 1000 African Americans, it is affecting about 70,000 to 80,000 Americans in the United States. Sickle cell is a death threatening disease, and the severity of symptoms can vary from person to person (Sickle cell disease (SCD), 2015). Some people have light conditions, but others can have severe conditions, which, mean they could be hospitalized. Characteristics of this disease are caused by a minimum of low blood cells, which is called anemia.
Sickle Cell Disease (SCD) (also known as Sickle Cell Disorder or Sickle Cell Anemia) is an inherited blood disorder where the red blood cells have abnormal sickle-shaped hemoglobin S (HbS) called sickle haemoglobin (National Heart Lungs and Blood Institute (NHLBI), 2015). The disease, according to medical sciences, is inherited from both parents as part of their genetic makeup and is usually caused by some abnormalities in haemoglobin which is a protein in red blood cells that conveys oxygen through the body. Whereas normal red blood cells are round, in people with sickle cell anemia, a defective substance in red blood cells changes the shape of the cells. The normal haemoglobin called haemoglobin A (HbA) is replaced by HbS which later becomes
Moreover, Mr. Johnson’s younger brother died in adolescence from the disease, after many painful and debilitating attacks. He thus knew it was a possibility that he himself was a carrier. Mr. Johnson also knew that the trait is fairly common among African Americans, about one in twelve is a carrier, so there was a good chance his fiancée was a carrier too. Ms. Sanford knows of no sickle cell disease in her immediate family, but she is in a racial group with a relatively high rate of
Sickle-cell anemia is a genetic disorder that makes your body produce red blood cells that are abnormal in shape. This disease is also widely known as hemoglobin SS disease. Unlike normal red blood cells, sickle cells are rigid and tenacious. Due to their shape and rigidness, they can block blood flow. In turn, this could cause organ damage to the body. Sickle cells are also fragile and die very easily due to the fact sickle cells have a lifespan of twenty days instead of the normal one hundred and twenty days for normal red blood cells.This causes the body to have a lower blood cell count, hence the name anemia in sickle cell anemia.
Sickle cell was first discovered by Dr. Ernest irons that was a hospital intern who look over a patients cell which seem to be different he called them “sickle cell shaped”. Sickle cell is know as a negro inherited diseases which is incorrect not only African Americans have this diseases. Many other races are effect by this diseases and regions all over the world such as India, Mediterranean countries, South American. In this case sickle disease work kind of like vaccination for malaria another diseases, this is the most common inherited disease in American. Anyone who has sickle trait and have a baby with someone who has the trait also can bring a baby into the world the world with SCD.
Sickle cell disease is an inherited disease where the red blood cells in the body are produced abnormally by bone marrow as crescent shaped red blood cells. Unlike normal red blood cells, sickle shaped cells are unable to deliver much oxygen to other parts of the body due to the abnormal hemoglobin. Sickle cell’s are stiff and sticky and tend to clump together between blood vessels that can cause pain, damage to the organs, and infections. If a child inherits this disease they can be healthy throughout their life or need special care. “In the United States, SCD is most common among blacks and Hispanics. SCD affects about 1 in 500 black births and about 1 in 36,000 Hispanic births in this country. SCD is also common among people with family from Africa, the Caribbean, Greece, India, Italy, Malta, Sardinia, Saudi Arabia, Turkey or South or Central America (March of Dimes)”.
Sickle cell anemia is an inherited disease in mostly people of Mediterranean, African, or Southeast Asian heritage which occurs when a person inherits the genes for sickle hemoglobin(NHLB). Sickle cell anemia is named from the shape that the red blood cells take because they become a crescent/sickle shape. Normally these red blood cells are flexible and round, but with sickle cell anemia they become rigid and sticky(Mayo Clinic) This shape inhibits the normal functions of red blood cells and they also cause blockages in blood flow to the limbs. The signs and symptoms of the disease vary, ranging from mild symptoms to drastic and hospital inducing health problems. There currently exists no widely available cure for sickle cell anemia, but as time passes and more research is done it is hopeful that there will be a cure.
Sickle Cell is a disease that affects many people in the world today. It is the number one genetic disorder in the United States. Sickle Cell is deficient hemoglobin. Hemoglobin is what functions in providing oxygen to the cells in the body. The sickle shape comes from the atypical hemoglobin s molecules. Hemoglobin molecules are composed of two different parts called the alpha and beta. The beta subunit of the hemoglobin molecule has a mutation in gene, on chromosome 11 which produces the change in the red blood cell shape causing them to die and not reproduce accurately. The change in shape causes the red blood cells to get stuck in the blood vessels and block the effectiveness of oxygen transport causing pain and organ damage to the body. This disease does not have a cure and some common treatments are used to help patients live with the disease. Some treatment options are antibiotics (penicillin) to prevent infections, blood transfusions, folic acid that help produces new blood cells. These are just some of the current treatments for Sickle Cell.
Sickle cell anemia occurs when a person inherits two abnormal genes (one from each parent) that cause their red blood cells to change shape. Instead of being flexible and round, these cells are more rigid and curved in the shape of the farm tool known as a sickle - that's where the disease gets its name. The shape is similar to a crescent moon.
Sickle cell anemia is a genetic disorder that erythrocytes tolerate sickle shape red blood cells. These red blood cells are easy to damage, which leads to hemolytic anemia. Abnormal hemoglobin is fragile to low oxygen conditions within the body. It loses the blood solubility, and then forms thick strands called polymers. This gives the abnormal shape, called Sickle cell.
Sickle Cell Disease is a condition where there is not enough healthy red blood cells to carry oxygen throughout the body. Another name for sickle cell disease is sickle cell anemia. Sickle cell anemia is inherited as a simple recessive condition. In normal red blood cells, the cells are usually flexible and round. However, in sickle cell disease the red cells become rigid and sticky. They are shaped like sickles or crescent moons. Because these cells are irregular, they can get stuck in small blood vessels. The small blood vessels slow or block blood flow. Without enough red blood cells in circulation a person's body cannot get the adequate amounts of oxygen needed to feel energized.
Sickle cell anemia is a genetically inherited and is a lifelong disease. Sickle cell anemia affects the red blood cells because it causes the cells to be crescent shape instead of how a normal cell looks like: an oval disk. This causes the circulation of the blood flow throughout the body to be clogged more often because people with sickle cell tend to have more blood clots. This also exhausts the body a lot more and people with this particular disease are more likely to get winded by a short physical activity. Sickle cell disease is caused by a mutation in the beta-globin gene. The main symptoms of sickle cell are shortness of breath, fatigue, difficulty breathing, deterioration of athletic performance, weakness, headaches, and dizziness. Another set of key features that
Sickle cell anemia is an inherited blood disorder that affects the hemoglobin responsible for carrying oxygen throughout the body. (Centers for Disease Control and Prevention, 2010). This means that, unlike normal hemoglobin in which cells are smooth and round like the letter "O," that can pass through the vessels in our bodies with ease, sickle hemoglobin cells are rigid and form into the shape of a sickle, or the letter "C." The cells are also sticky and hence, cannot travel through small blood vessels. Consequently, they tend to cluster together and cause a blockage in the blood vessels and stop the movement of healthy oxygen-carrying blood.