Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Sarcoidosis
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: Sarcoidosis
Sarcoidosis is a granulomatous inflammatory condition with multisystem involvement of unestablished etiology. A century has passed by since this condition was first described by Hutchinson, however there still remains a serious lack of awareness regarding this illness amongst the healthcare professionals involved in treating children. Epidemiology: The condition, although more common in the age group of 20 - 45 years, can very well involve children of any age. It is feared that due to lack of awareness and nature of the illness, cases may remain undiagnosed or misdiagnosed. Added to this is the paucity of large scale epidemiological studies in children, that has resulted in underestimation of actual prevalence and incidence in the community. Data available from India is largely that of adult population. Worldwide data suggests that the disease is influenced by racial background and geographical location in terms of prevalence, clinical presentation and progression of illness. In one of the recent studies done in Denmark, where the prevalence rate is known to be high, incidence reported in children aged 14-15 years was 1.02 per 100000 and 0.06 per 100000 in children under 4 years of age. Etiopathogenesis: Etiopathogenesis is not completely understood, but exaggerated cellular immunity is considered to be central in the pathogenic process leading to granuloma formation. In a genetically predisposed individual, pathogenic and non-pathogenic environmental antigen triggers a cascade of inflammatory responses with release of excessive chemokines, cytokines and interferons that interact to form granuloma and fibrosis. Persistence of granulomas perpetuate further inflammatory process. Significant role of MHC class II molecules in the... ... middle of paper ... ...hamide, ciclosporin and anti TNF alpha agents. There has also been mention in case reports of use of thalidomide and chloroquine or hydroxychloroquine in moderately severe disease. Guarded prognosis is often given when the disease starts early in life. Late onset disease has variable prognosis and depends on various factors including race and geographical location. The disease may show spontaneous remission in some. Recurrences of the disease after remission has also been noted and hence long term follow up of patients after remission is advisable. Often the overall prognosis is felt to be generally good with timely instituted treatment. However the first step in treating depends on prompt recognition and diagnosis of the illness. The popular saying - ‘Eyes cannot see what the mind does not know’ applies well to this challenging and difficult to diagnose condition.
With the diagnosis of disease comes many life altering events. Someone’s world can be turned upside down at the moment it is recognized and these people have no choice but to adjust. Sometimes, the disease has the power to inhibit even the most simple activities, or in some lucky cases, inhibit almost none.
The incidence rate for children between 0 and 19 years old was 5.13 per 100,000. For adults over 20 years of age, the incidence rate was 26.8 per 100,000. The rate was higher in females (22.3 per 100,000) than males (18.8 per 100,000).
Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July 14, 2012, from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001471/
One very special case can be displayed by none other than David Beckham, the famous international football star. He says that he has tried various treatments, but the biggest success came from learning to live with the disease (Healthguru, n.d.). His family is also very supportive of his condition, which shows how important family support is. Quoted by Victoria Beckham, his wife, “We've got three fridges - food in one, salad in another and drinks in the third. In the drinks one, everything is symmetrical. If there's three cans, he'll throw one away because it has to be an even number” (Frith,
symptoms are not noticeable until the person with the disease reaches their middle years, approximately 30-50. The disease progresses rapidly once the first signs start showing. Within years the symptoms will get severely worse and the person’s quality of life will drastically decrease. Some of these symptoms include uncontrollable body movements, loss of mental stability, and loss of the ability to think. In the later years of the person’s life they will need assistance wit...
The disease has an unpredictable clinical course. This means it’s hard to give a prognosis in any single patient.
It is commonly diagnosed in childhood but can arise at any age and is not currently
globally spread. The symptoms of this illness are quite defined and are very recognizable. Cause
...agnosed at a later stage, most people die within two years of diagnosis and treatment.
symptoms between the ages of 30 and 50, but has been known to show itself in
Girls with this syndrome may have many middle ear infections during childhood; if not treated, these chronic infections could cause hearing loss. Up to the age of about 2 years, growth in height is approximately normal, but then it lags behind that of other girls. Greatly reduced growth in height of a female child should lead to a chromosome test if no diagnosis has already been made. Early diagnosis is very importance in order to be able to give enough correct information to the parents, and gradually to the child herself, so that she has the best possibilities for development. Early diagnosis is also important in case surgical treatment of the congenital heart defect (seen in about 20 per cent of cases) is indicated.
complications of this disease. The Cause of this disease is still a mystery to be solved. Through
The purpose of this paper is to analyze, diagnose, and to determine a proper treatment plan to work toward the beneficial prognosis for the individual indicated within the case study.