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Article #1: Prevalence/Incidence
Global Estimates of the Prevalence of Diabetes for 2010 and 2030
Diabetes is a disease that continues to increase worldwide. It continues to be a large problem in both developed and undeveloped countries. This article summarizes a study that focused on the future estimated number of people diagnosed with diabetes from 2010 to 2030. The findings were that the amount of people diagnosed with the disease would increase worldwide by about 1% (increasing by about 200 million more diagnosed adults ranging from ages 20-79 years old). It does not sound like much, but the number of people diagnosed with diabetes in underdeveloped countries would increase by about 69% by 2030 and the number diagnosed in developed countries would increase by about 20% by 2030.
This article goes to show that the problem of diabetes is not going away anytime soon. It is a growing epidemic that continues to affect millions of people worldwide. I think that more people need to be educated about diabetes and their personal lifestyle choices that affect their health in such an immense manner. I know that it is easier said than done, but knowledge is power. And in this case, the more knowledge people have about diabetes and diabetes prevention, the more the numbers of people diagnosed with the disease will go down.
Article #2: Treatment
Liraglutide: Effects Beyond Glycaemic Control in Diabetes Treatment
The article expresses the correlation of obesity and patients with type 2 diabetes and how the GLP-1 receptor, Liraglutide, can stimulate weight loss in these obese patients. Because of their high levels of insulin resistance, obese individuals have a greater chance of being diagnosed with Type 2 diabetes. After performing clinical trials by treating patients diagnosed with Type 2 diabetes, it was found that Liraglutide does stimulate weight loss as well as increase beta-cell function. Scientists believe that Liraglutide can decrease the number of patients diagnosed with Type 2 diabetes as well as prevent Cardio Vascular Disease.
I found this article to be very interesting. I knew that obesity played a large role in the diagnosis of Type 2 diabetes, but I did not know the lengths to which scientists are trying to decrease obesity through certain hormone injections. I think that the growing obese population in the United States should adopt a healthier overall lifestyle before having to turn to hormone injections for weight loss. Even though the use of Liraglutide can lower both Type 2 diabetes and Cardio Vascular Disease, so can a healthy lifestyle.
During the year 1889, two researchers, Joseph Von Mering and Oskar Minkowski, had discovered the disease that is known today as diabetes. Diabetes is a disease in which the insulin levels (a hormone produced in unique cells called the islets of Langerhans found in the pancreas) in the bloodstream are irregular and therefore affect the way the body uses sugars, as well as other nutrients. Up until the 1920’s, it was known that being diagnosed with diabetes was a death sentence which usually affected “children and adults under 30.” Those who were diagnosed were usually very hungry and thirsty, which are two of the symptoms associated with diabetes. However, no matter how much they ate, their bodies wouldn’t be able to use the nutrients due to the lack of insulin. This would lead to a very slow and painful death. In 1922, four Canadian researchers by the names of Frederick G. Banting, Charles H. Best, John J.R. MacLeod, and James B. Collip had discovered a way to separate insulin in the pancreas of dogs and prepare it in such a way so that it can be used to treat diabetic patients. In the year 2008, there were 1,656,470 people who suffered from diabetes in Canada, and by 2010, it is predicted that this disease will take over the lives of 285 million people . Although there is no cure for diabetes, the treatment of prepared insulin is prolonging the lives of diabetics and allowing them to live freely. The discovery of insulin was important and significant in Canada’s history because Banting was a Canadian medical scientist who had a purpose in finding a treatment for diabetes, its discovery has saved lives and improved the quality of life of those suffering from this disease, and it showed the world Canada’s medical technology was ...
Diabetes mellitus, habitually referred to as diabetes is caused by a decline in insulin secretion by the cells of the pancreatic islet resulting into a surge in blood glucose concentration, a condition known as hyperglycemia. Diabetes insipidus is a disorder defined by the secretion of huge quantities of highly diluted urine, this is regardless if a reduction in fluid intake. This is as a result of a deficit of anti-diuretic hormone (ADH) also known as vasopressin produced by the posterior pituitary gland. The disorder diabetes mellitus is associated by extreme reduction in weight, a higher urge for urination, also known as polyuria, higher levels of thirst (polydipsia) and an extreme craving to eat known as polyphagia. This disorder has been categorized as Type 1 or insulin dependent diabetes and Type 2 or non-insulin dependent diabetes another type is the Gestational diabetes. The Type 1 diabetes mellitus is portrayed by a deficiency of the insulin-secreting beta cells of the islets of Langerhans found in the pancreas, this leads to a shortage of insulin. The principal cause for this deficiency of beta cells is a T-cell mediated autoimmune onslaught. In children, Type1 diabetes is known as juvenile diabetes. The Type 2 diabetes mellitus is as a result of insulin resistance or diminished insulin sensitivity coupled to a reduction in insulin production.
Obesity remains an extremely serious issue worldwide. Once considered a problem for wealthier counties, overweight and obesity are now dramatically increasing in low and middle income countries (WHO, 2011). In American, the rates of obesity continue to soar. CDC (2009) recognizes obesity as a risk factor for diabetes, heart disease, high blood pressure, and other health problems. According to NHANES over two-thirds of the US are overweight or obese, and over one-third are obese (CDC, 2009). Treatment for this illness varies; it may include the incorporation of diet, exercise, behavior modification, medication, and surgery. Since there is no single cause of all overweight and obesity, there is no single way to prevent or treat overweight and obesity that will help everyone (CDC, 2009).
Jost, Kenneth. “Diabetes Epidemic: why is this serious disease on the increase?” The CQ Researcher (March 9, 2001): 185-200
Diabetes is becoming an epidemic. In fact, in 10 years many experts believe that people who suffer from diabetic is going to double. Kids who are as young as 8 years old are now borderline type 2 diabetics.
"Treating Obesity Vital For Public Health, Physicians Say." Science Daily. 2006. Web. 10 May 2014. .
Magliano, DJ, Shaw, JE, Shortreed, SM, Nusselder, WJ, Liew, D, Barr, EL, Zimmet, PZ & Peeters, A 2008, ‘Lifetime risk and projected population prevalence of diabetes’, Diabetologia, vol.51, pp.2179-2186, viewed 15th May 2011.
Carek and Dickerson (1999). Current Concepts in the Pharmachological Management of Obesity. Drugs, 57(6), 883-904.
according to the National Institute of Health, Type 2 Diabetes is responsible for 30% of cases in this country. This example explains how Zin...
Diabetes Mellitus is a chronic health condition in which the level of glucose in the blood is higher than usual. Type 1 diabetes occurs when the pancreas does not create enough insulin and type 2 diabetes occurs when insulin is produced, but is not adequate in lowering blood glucose levels or there is resistance to the insulin (Edwards, 2007, p. 9). Diabetes mellitus is the leading cause of end-stage kidney disease, foot and leg amputations, and new cases of blindness in the United States (Ignatavicius & Workman, 2010, p. 1465-66). People with type 1 diabetes are required to take insulin to manage their glucose levels. People with type 2 diabetes are usually prescribed oral medications such as sulfonylurea agents, meglitinide analogues, or biguanides to help control their glucose levels. Twenty to 30% of people with type 2 diabetes require insulin therapy as well (Ignatavicius & Workman, 2010, p. 1471). In addition to medication therapy, diet and weight control can help manage both type 1 and type 2 diabetes. Because diabetes mellitus can cause such severe complications, it is important that people with diabetes understand the importance of certain health and lifestyle choices, such as their diet and weight to manage their disease. Patients with diabetes mellitus should pay special attention to the amount of carbohydrates, protein, fat, and minerals that are included in their diet. Monitoring these components of their diet, along with weight management, can help control their diabetes mellitus.
Diabetes mellitus is a group of metabolic disorders which is characterized by hyperglycemia due to insulin deficiency or resistance or both reasons. (1) According to that diabetes mellitus can be divided as type I and type II. This is common and its incidence is rising, 171 million people had diabetes in 2000 it is expected this condition to be doubled in 2030. It is spread in all the countries and therefore has become a major burden upon healthcare facilities. (2)
There is an epidemic running rampant across the United States and most people do not know the effects it has on society; this epidemic is none other than obesity. In the last thirty-five years, the obesity rate has more than tripled. Obesity has many ill effects and is the cause of many diseases. Washington Post journalist Wil Haygood, elaborates, “A lot of our medications are for ‘disease states,’ such as Type 2 diabetes, hypertension, things that can be adversely affected by increased weight” (411). Speaking with a pharmacist, Haygood explains how obesity can lead to serious disease and further health implications that are difficult to overcome.
Zimmet, P., K.G. Alberti, and J. Shaw.2001. Global and societal implications of the diabetes epidemic. Nature 414 (December 13): 782-86
In conclusion, diabetes is a serious disease and can be life threatening. With the right research and implementation of new studies diabetes can be reduced among the populations. We as a people need to realize this epidemic and all get together and beat it. Restaurants need to stop putting chemicals and unnecessary fats in their food. Not only diabetics but everyone should educate themselves on what is going in your body when you eat. Also, exercising and getting off the couch, in children, needs to be addressed and that alone would help reduce diabetes in the younger population. I can’t stress enough on education. If you know what you are eating or how you are exercising you protect yourself from poor health and live a great life. Type 2 diabetes can be dwindled down with a conscious individual and group effort.
This multi-factorial condition is associated with increased risk of other conditions, such as hypertension, type 2 diabetes and cardiovascular disease (Slentz et al., 2004). In 2005, the overall costs of obesity were $56.6 billion in Australia (Colagiuri et al. 2010). By eradicating obesity, not only would the economic burden on the healthcare system become significantly reduced, but the prevalence of these debilitating conditions would also decline. Anti-obesity drugs can be used to ensure sustainable, long-term weight management in patients rather than making drastic lifestyle changes. The currently available weight loss drugs, which have been FDA-approved for long-term use, are lorcaserin and orlistat (Kim et al., 2013). They act to centrally