A relatively new diagnosis in the medical field is Eosinophilc Esophagitis. This disease has emerged all around the world and became a more common diagnosis beginning in the 2000’s. According to doctors at the Cincinnati Children’s Hospital Medical Center, 1-4 in 10,000 people live with this disease (Cincinnati, 2012, p. 1). Food allergies often accompany this disease, which may be why it is becoming better known. The pathophysiology behind Eosinophilic Esophagitis is extensive, and includes the parts of the body that are effected, normal function, symptoms and cause of symptoms, diagnosis, physiology, and treatment. Eosinophilic Esophagitis is a disease that affects the esophagus. Other parts of the gastrointestinal tract can also be affected but if that is the case, the disease is renamed according to the area affected. Eosinophilic Esophagitis (EE) causes the esophagus to be narrower than usual, known as esophageal stricture. This is due to the presence of eosinophils. Eosinophils are white blood cells, produced in bone marrow, that are most commonly found in the gastrointestinal tract. They normally function by killing off microorganisms, such as parasites. In EE, certain stimuli can cause increased production and buildup of excess eosinophils. Since the esophagus narrows due to this disease, dysphagia and food impaction commonly occur. Eosinophils can also cause thinning of the esophageal lining. This makes the lining more susceptible to being punctured by contents traveling down the esophagus. The esophagus is also affected by the disease because it is linked to acid reflex. Reflux can cause break down and damage to the esophageal lining. Finally, Peristalsis or the involuntary movement of food through the esop... ... middle of paper ... ...4) Eosinophilic esophagitis. The New England Journal of Medicinc. Retrieved From http://www.nejm.org/doi/full/10.1056/NEJM200408263510924#t=article Nurko, S., & Furuta, T. G. (2006). Eosinophilic esophagitis. Retrieved From http://www.nature.com/gimo/contents/pt1/full/gimo49.html The American Partnership for Eosinophilic Disorders (2008). Eosinophilic associated gastrointestinal disorders: About EGID. Richmond, Texas: The American Partnership for Eosinophilic Disorders. [Brochure] The American Partnership for Eosinophilic Disorders (2008). Eosinophilic esophagitis: About EE. Richmond, Texas: The American Partnership for Eosinophilic Disorders. [Brochure] The International Gastrointestinal Eosinophil Researchers. A guide to eosinophilic esophagitis in children and adults. Flourtown, PA: Children’s Digestive Health & Nutrition Foundation. [Brochure]
•Jose symptoms is derived from a disorder called Gastroesophageal reflux disease (GERD) occurring in the digestive system with the consumption of food, irritating the esophagus generally causing notable clinical symptoms such as the following: vomiting, chronic cough, angina, & regurgitation immediately after the consumed food. Jose's experience of the lump in his throat is caused by esophageal sphincter pressure.
Crohn’s disease is a chronic inflammatory condition of the gastrointestinal tract that belongs to a group of conditions known as Inflammatory Bowel Diseases (IBD). Crohn’s disease is defined as a transmural inflammation with skip lesions that can affect the gastrointestinal tract from mouth to anus (Mulder, Noble, Justinich, & Duffin, 2013). In Crohn’s disease the immune system attacks the gastrointestinal system and can cause the digestive tract to be chronically inflamed. Crohn’s disease has a variety of symptoms that include abdominal discomfort, diarrhea, rectal bleeding, fever, and weight loss. Crohn’s disease can also affect the joints, skin, eyes, and cause kidney stones, gallstones and other ailments (Warner & Barto, 2007).
IBS is a functional GI disorder, meaning it cannot be explained by any specific structural or biochemical abnormality. The disorder is subdivided into three different types, which are named on the basis of the predominant symptom – IBS-D (diarrhea-predominant), IBS-C (constipation-predominant), IBS-M (mixed diarrhea and constipation). Clinical presentation varies considerably with regard to the quality of the predominant feature and the overall severity of symptoms. Formal diagnosis is based on the most recent Rome III criteria, which require that a patient experience recurrent abdominal discomfort of at least 3 days per month over the previous 3 months, with a total symptom duration of at least 6 months, in...
2. No evidence to suggest reflux esophagitis nor other changes suggesting eosinophilic esophagitis. Pathology pending.
A common condition that is associated with GERD and LES problems is having a hiatal hernia. A hiatal hernia is when you have a larger than normal opening in the diaphragm where the esophagus passes through. Since this opening is larger, the stomach begins to enter this opening. When you eat, the stomach and esophagus ...
The second type of dysphagia is called Esophageal dysphagia. This type dysphagia is characterized by the diminished ability to move food through the esophagus (Eisenstadt, pg. 18). This may cause chest pain or cause the patient to spit up their f...
As the acid backwashes into the esophagus the lining in the lower esophagus can become irritated an start to become narrow (esophageal stricture) as well as sores can form which causes bleeding (esophageal ulcer). If this condition or changes to the lower esophagus progresses it could lead to esophageal cancer ( Barrett's esophagus).
Approximately 8% of the world’s population is affected by dysphagia. Some of the factors that can cause dysphagia are obstruction, inflammation, paralysis, altered motor function, and functional conditions. While the most common cause of dysphagia is a stroke. A stroke can be caused by a blood clot and this in turn shuts off blood supply and oxygen to the brain resulting in potential brain cell death. GERD or gastro esophageal reflux disease is also a common chronic disease that results in dysphagia. This is where the digestive system refluxes stomach acids into the esophagus causing irritation. Over time this can result in the esophagus narrowing and many times you will see patient’s food get
Epiglottitis is a potentially life-threatening condition that occurs when the epiglottis inflames and swells, causing the airway to become blocked (Mayo Clinic, 2018). The epiglottis is leaf-shape flap of cartilage located in the throat behind the tongue and in front of the larynx. It is made of yellow elastic cartilage tissue, lined with a mucous membrane. The epiglottis is usually resting in the upright position which allows an opening in the trachea for air to pass through (Heller & Zieve 2017). But when a person is eating and swallowing the epiglottis folds over so that the trachea becomes blocked off and that way no food or water enters the trachea and instead goes through the esophagus. The epiglottis is able
“What is Cystic Fibrosis?.” National Heart, Lung, and Blood Institue. U.S. Department of Health and Human Services, 2011. Web. 18 Nov. 2013.
This research was done by Cornelius P. Dooley, Hartley Cohen, Patrick L. Fitzgibbons, Madeline Bauer, Maria D. Appleman, Guillermo I. Perez-Perez, and Martin J. Blaser. It was done at the Departments of Medicine (C.P.D., H.C., M.B.) and Pathology (P.L.F., M.D.A.), Los Angeles County-University of Southern California Medical Center, and the Medical Service, Veterans Administration Medical Center Denver (G.I.P. P., M.J.B.), the Section of Gastroenterology, Department of Medicine, USC School of Medicine, 2025 Zonal Ave., Los Angeles, CA 90033. It was presented in part at the 89th annual meeting of the American Gastroenterological Association, New Orleans, LA.
Human race is known to have developed numerous allergies to various known and unknown allergens. An extreme allergic reaction which can be “life-threatening”. (Mydr.com.au, 2014) is referred to as Anaphylaxis.It is a “medical emergency”(Lloyd & Sisman,2013).Statistics indicate that maximum deaths occur due to allergic reactions of various medicines. The other causative agents can be insects, food, latex, hair dye, etc(Lloyd & Sisman,2013). The most common trigger to stimulate anaphylaxis among children are food products such as peanuts, dairy, seafood etc. Exposure to any of these allergens can result in severe anaphylactic attack within 20 minutes.(Australian Resuscitation council, 2012).However the doctors discuss the history of symptoms occurring in children suffering with peanut allergy before declaring them to be anaphylactic and prescribing medication. (Unknown, 2014). Symptoms of anaphylaxis may occur in varied forms depending upon the severty of the reaction. For instance in mild cases swelling of lips, eyes or face occurs along with hives, rash, tingling of mouth and vomitting accompanied with abdominal pain. Nevertheless in extreme conditions the former symptoms may be accompanied with noisy breathing, wheezing, hoarseness and unconsciousness. (Lloyd & Sisman,2013).
Inflammatory bowel disease is a life long disease, and it particularly targets the gastrointestinal tract (GI tract), which consists of the mouth, esophagus, stomach small intestine, large intestine (appendix, cecum, colon (ascending, transverse, descending, and sigmoid), and rectum), and anus. The gastrointestinal tract is very important to the human body; some of its functions include mechanical and chemical digestion of food, the movement of food and waste from mouth to anus, secretion of enzymes and mucus, and the absorption of nutrients. These are some reason why it’s so destructive when this part of the body becomes impaired or even damaged.
The first is that it may be because of a weakened lower esophageal sphincter or LES. This is the valve that keeps the stomach acid inside the stomach and prevents the acid from coming in contact with the esophagus. A weakened LES is one of the most common symptoms of GERD or Gastroesophageal Reflux Disease.
National Digestive Diseases Information Clearinghouse (NDDIC). Skip NavigationU.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, 2014. Web. 20 May 2014.