Pain and Painkillers

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In this discussion, I will be looking at the different forms of pain and how this pain is caused within the body. The number of different types of drugs used to treat pain is forever expanding but I will examine the main types of painkiller, how they were discovered and how they work to relieve the symptoms of pain.

There are many different types of pain which can be categorised depending on how the pain is caused and how long the pain lasts. If pain results from tissue damage then it is called nociceptive pain and this includes pain from pressure applied outside of the body, like a cut or a burn, or from pressure inside the body such as a tumour. Another type of pain is neuropathic pain which is pain experienced when there is damage to the actual nerves or central nervous system within the body. It can be caused by conditions such as HIV, cancer and Multiple sclerosis1,2.

Acute pain is mainly to provide a warning signal that something is wrong, for example if you put your hand too near a hot object, pain is experienced which causes you to move your hand away before permanent damage is done. The pain experienced is immediate, usually of short duration and can usually be diagnosed and treated. Chronic pain is continuous pain that persists for a longer period of time and can last up to a lifetime. This type of pain causes the patient permanent discomfort and can severely affect the everyday lifestyle of the sufferer. Arthritis and back pain are common types of chronic pain1,2.

The feeling of pain is caused when damaged tissue stimulates the release of messenger chemicals called neurotransmitters which in turn stimulate the nerve endings and electrical impulses are sent to the brain12.

The body has its own mechanisms for relievin...

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