Thermal methods of analysis have been in use for quite a long time. Their application in the analysis of pharmaceutical materials has made it possible for pharmacists and researchers to understand their contents and characteristics. However, thermal methods have several disadvantages that have led researchers to opt for nano-thermal methods of analysis. Nano-thermal analysis methods use special resolution imaging potential that is enhanced by the availability of atomic force microscopy and thermal analysis methods.
Nano-thermal analysis methods are also known as micro-thermal procedures and they use the principle of characterizing highly localized materials on a micrometer. The characterization is then changed from a micrometer scale to a sub-micrometer scale with the temperature being regulated to the specified units. The application of nano-thermal analysis methods started towards the end of the 20th century. Although it has been applied in several other fields including microelectronics, its application in pharmaceuticals has not been that popular.
The nano-thermal analysis method is capable of studying the specific regions of a sample irrespective of its composition. In a multi-component sample, the analysis methods make it possible for the researchers to distinguish between the different components and identify the different characteristics found in each of the sample (Craig, 2002). During the analysis of any sample, the nano-thermal method does not necessarily require the physical alteration of the sample. In its place, it is capable of analyzing any sample through surface studies.
One of the characteristics of the nano-thermal analysis is its localized nature. This me...
... middle of paper ...
...gs must be within the medical specifications and without proper analysis; the consumers may be subjected to dangerous components within a drug.
The analysis is therefore one of the most effective methods of ensuring that each drug being prescribed to patients is safe. It also ensures that all drug components are understood in terms of their structure and chemical behavior. This understanding is very important in the manufacture of drugs and other pharmaceutical products.
Craig, D. Q. (2002). Pharmaceutical Applications of Micro-Thermal Analysis. Journal of Pharmaceutical Science, 91(5), 1201-1213.
Dai, X., Reading, M., & Craig, D.Q.M. (2008). Mapping Amorphous Material on a Partially Crystalline Surface: Nanothermal Analysis for Simultaneous Characterisation and Imaging of Lactose Compacts. Journal of Pharmaceutical Science, 98, 1499–1510.
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