Discovered in 1861 by Guillaume B.A. Duchenne, muscular dystrophy is a very unfortunate disease to inherit. Muscular dystrophy is a group of heredity disorders characterized by progressive muscle weakness and wasting. The trait for muscular dystrophy may be transmitted as an autosomal dominant. In this case, if some original carrier of the disease had children, the children would have a fifty-fifty chance of inheriting the disease. It is also carried as an autosomal recessive trait, in which case the offspring of the original carrier would have a very small chance of inheriting the trait. Muscular dystrophy is also a sex-linked trait. If someone carrying the trait for the disease conceived a male, the newborn boy would have a very high risk of later on developing the disease. Incidence of muscle dystrophy is estimated to be one in 3-4,000 male births. There are also about 15,000 muscular dystrophy patients in the United States at any given time. Those who have muscular dystrophy are missing the protein called ?dystrophin.? Before scientists ever discovered the missing protein, the tested carriers for the disease had a high presence of elevated serum levels of creatine and phosphokinase. The disease can now be found for a prenatal diagnosis. Individuals who inherit this disease will have a rapid progression of symptoms. Walking becomes difficult, and skeletal contractures and muscle atrophy follows. They also usually need wheelchairs by adolescence. Half of the receivers of the disease unfortunately develop some form of mental retardation and most never make it past there teenage years. Currently, options for a treatment of muscular dystrophy are limited. Physical therapy may slow down the progression of deformities. Such devices as wheel chairs, crutches, or secondary orthopedic limbs may permit mobility. There are also a few medications that can help relieve pain and stiffness in the muscles. The Muscular Dystrophy Association, the Parent Project Muscular Dystrophy Research and the Children's Hospital of Pittsburgh helped fund a research project for the disease. The research, carried out by Johnny Huard, Ph.
Muscular Dystrophy is a diverse group of disease which involves the weakness and wasting of muscles and leads to many other problems in physiological system. It is because of mutation in gene related to contraction and relaxation of muscles. Although recently no perfect treatment option is available for it but in nearby future cure of this disease will be available due to advanced technology and methods like gene therapy and stem cell technology.
Spinal Muscular Atrophy affects about 8 out of every 100,000 live births and also causes death among more babies than any other genetic disease out there. About one in every forty people has this gene in them but may not have SMA so they are a genetic carrier. But in order for a child to have SMA, both parents have to carry the mutated gene and passed it to the child. Therefore this causes the child to have double copies of the abnormal gene. About 1 in 40 men and 1 in 80 women are carriers of the gene.
DMD also known as muscular dystrophy is muscular disease that occurs on young boys around age four to six. Muscular dystrophy is genetically transmitted disease carried from parent to offspring. This disease progressively damages or disturbs skeletal and cardiac muscle functions starting on the lower limbs. Obviously by damaging the muscle, the lower limbs and other muscles affected become very weak. This is ultimately caused by the lack dystrophin, a protein the body produces.
Muscular Dystrophies are genetic disorders that are distinguished by degenerative muscles and weakness in the muscles. Duchenne muscular dystrophy is a dominant sex-linked disorder that mostly affects males, and it affects one in 3,500 males (Furlong, 2015). Males inherit Duchenne Muscular Dystrophy when they get an X chromosome (they inherit the chromosome from their mother) with a mutated dystrophin gene. Since males only have one X-chromosome (males have XY, females have XX), they are more vulnerable. If a female inherits only
Chronic Wasting Disease is a highly transmissible, deadly neurodegenerative disease that affects cervids in North America (Belay et al., 2004; Saunders et al., 2012). There are only four types of cervid that are known to get this disease which include elk, mule deer, white-tailed deer, and moose (Chronic Wasting Disease Alliance). It has been classified has a transmissible spongiform encephalopathy (TSE), otherwise known as a prion disease (Belay et al., 2004). A prion is an irregular, pathogenic agent that causes abnormal folding of specific proteins called prion proteins. These proteins are mostly located in the brain (Chronic Wasting Disease Alliance). The abnormal folding of this protein causes neurodegenerative diseases in a variety of species including humans, sheep, cattle, and deer (Abrams et al., 2011).
Muscular Dystrophy is a genetic disorder in which your muscles drastically weaken over time. Muscles are replaced with “connective tissue,” which is more of a fatty tissue than a muscular one. The connective tissue is the tissue that is commonly found in scars, and that same tissue is incapable of movement. Although Muscular Dystrophy affects muscles in general, other types affect certain groups of muscles, and happen at different periods throughout a lifetime. For example one of the most common types, Duchenne Muscular Dystrophy, targets muscles in the upper thigh and pelvis. The disease is displayed throughout early childhood, usually between ages four and seven. This genetic disorder occurs only in boys. People have difficulty sitting up or standing and lose their ability to walk in their early teens. Sadly most people die by the age of twenty. A second common type, Becker’s Muscular Dystrophy affects the same muscles as Duchenne, but first appears in teenage years. Most people with Becker’s only live into their forties (Fallon 1824-1825).
Body image has primarily been a problem for females. Recently, however, this view has opened up and has been seen in males. While women fixate on looking thin and slim, men’s obsessions are on the opposite spectrum, where guys want to be big, thick, and muscular. First known as "reverse anorexia", and now properly called muscle dysmorphia this obsessive compulsive disorder makes individuals believe that they are small and muscularly undeveloped and meanwhile they are moderately or highly muscular. This disorder is mostly seen in males and is rather unhealthy because it raises potential for self-esteem issues, steroid abuse, anti-social attitude, stress, over-meticulous diets and workout plans, and in worst case scenarios, suicide. In our society ideal body image for males has been put up to an impossible pedestal and the examples for the perfect physique are worsened by media causing this disorder to grow even further.
It is estimated that 1 out of every 5,600-7,700 boys ages 5-24 have Duchene or Becker muscular dystrophy. (“Data & Statistics,” 2012 April 6) Muscular dystrophy is a group of genetic diseases defined by muscle fibers that are unusually susceptible to damage. There are several different types of muscular dystrophy some of which shorten the affected person’s lifespan. (“Muscular dystrophy: Types and Causes of each form,” n.d.) There is a long history of the disorder but until recently there wasn’t much knowledge of the cause. (“Muscular Dystrophy: Hope through Research,” 16 April 2014) Symptoms are obvious and can be seen as soon as a child starts walking. (“Muscular Dystrophy,” 2012 January 19) Although muscular dystrophy mostly affects boys, girls can get it too. (“Muscular Dystrophy,” 2012 January 19) There is no cure for muscular dystrophy but there are several types of therapy and most types of muscular dystrophy are still fatal. (“Muscular Dystrophy: Hope through Research,” 16 April 2014)
 Mild, chronic depression has probably existed as long as the human condition, although it has been referred to by various different names. The DSM-III replaced the term “neurotic depression” with dysthymic disorder--which literally means ‘ill-humored’-and it was added to the Diagnostic and Statistical Manual of Mental Disorders, 1980
The thought of never being able to walk or crawl is unimaginable. We take for granted how truly blessed we are. Even the simple task of walking or even standing may seem like moving mountains to the children who suffer from Spinal Muscular Atrophy (SMA). Some go their whole lives without knowing what it is like to even crawl. SMA is the number one genetic killer in infants under two (What is Spinal Muscular Atrophy?) it affects people for the rest of their life and the disease is devastating, so why is it taking a backseat to other infant diseases such as SIDS?
Duchenne Muscular Dystrophy, also known as DMD, is the most common form of muscular dystrophy. Muscular dystrophy is a condition that is inherited, and it is when muscles slowly become more and more weak and wasted. Duchenne muscular dystrophy is a form of muscular dystrophy that is very rapid and is most commonly found in boys. In muscle, there is a protein named dystrophin. Dystrophin is encoded by the DMD gene. When boys have Duchenne muscular dystrophy, they do not produce enough dystrophin in their muscles. This causes weakness in their muscles. Parents can tell if their child has duchenne muscular dystrophy by looking for various symptoms.
Every male inherits an X chromosome from their mother and a Y chromosome from his father which makes him male. Females get two X chromosomes from each parent. With those two X chromosomes the female gets it helps her fight the one that does not have dystrophin protect her muscles. If the mother has a flawed gene there is a 50% chance that the son will have DMD. This makes the mother ‘the carrier’. The absence of dystrophin in the cells causes weakness to the muscles. Symptoms will show about at the age of 2 years-old. As they get older you will notice that it is affecting the body totally different. They have a sway back, their arms and legs look out of place. The male’s body that is just so badly affected has wheel chairs at a young age others have tiny crutches to help them elevate their body, helping with balance. It is very painful itself to your body.You can live up to the age of 25 years-old for the reason being that the disease is just damaging your muscles. During the process of aging with this condition there are ways to help you with the muscles. For example, they give you an opportunity to have therapy. Going to therapy helps them in some ways to build up a little more muscles even though the dystrophin is too strong it will still weaken the muscles.Lack of dystrophinweakening the muscle layer in the heart resulting in a condition called cardiomyopathy. As it affects the heart as well that puts more damaged to the males body. This
Duchenne's muscular dystrophy, also known as psuedohypertrophic muscular dystrophy, is a typical sex-linked disorder in which the muscles degenerate throughout a person's life. It literally means "faulty nutrition of the muscles. " Muscular Dystrophy has no cure, and this particular type of muscular dystrophy affects only males. One in 3,500 baby boys are born with this disorder and while survival is rare beyond the early 30s, death is usually caused by a respiratory disease.
"…a sort of death-in-life existence and the blessed relief of flopping into our unmade beds." John McManamy in (Mental Water Torture-Mild to Moderate Depression.) What he is describing is Dysthymia. Dysthmyia or Dysthymic Disorder is a type of mild depression (AAP, Diagnostic and Statistical manual of mental disorders). It is chronic, pervasive, and a disabling illness affecting up to 5% of the population (About Dysthymia).
Becker muscular dystrophy is similar to Duchenne muscular dystrophy and also has similar symptoms, but is much less severe. This is because the gene affected, dystrophin, is still partially functional. Therefore, the symptoms appear much later into one’s life and usually, the person affected is able to live for...