Mesenchymal Stem Cells Essay

Mesenchymal Stem Cells Essay

Length: 974 words (2.8 double-spaced pages)

Rating: Better Essays

Open Document

Essay Preview

According to the Department of Health and Human Services, heart disease is the leading cause of death in the United States (1). The medical community is constantly looking for new technologies and discoveries to treat heart disease more effectively. Methods include mechanical based therapies such as artificial heart valves and drug based approaches as with anticoagulant medications. Recently, exciting new discoveries have been made by the scientific community in the development of stem cell based therapies. If scientist could identify and cultivate cells that would reestablish oxygenated blood flow to damaged heart tissue and generate new muscle tissue it would change the landscape of cardiovascular medicine. Actually, this process has already begun as research focuses on a specific cell with these qualities, the mesenchymal stem cell.
Mesenchymal stem cells originate from the mesoderm, the middle germ layer of an embryo, and play a vital role in the formation of connective tissue such as bone, cartilage, marrow, fat and blood. They are also precursor cells that help to produce cardiac, skeletal, and smooth muscle. Mesenchymal stem cells are found in every organ of the body but are most commonly obtained from bone marrow. Mesenchymal stem cells are classified as multi-potent stem cells. Multi-potent stem cells can transform into many different cell types that are of the same lineage. These innate traits make them prime candidates for use in developing heart disease treatments. While research and clinical trials are still in their infant stages, mesenchymal stem cells possess many desirable characteristics necessary to successfully regenerate heart tissue and restore heart function after heart attack.
One of the most important...


... middle of paper ...


...the Treatment of Myocardial Infarction.” Heart, Lung and Circulation 18 (2009): 171-80. Web.
Meirelles, da Silva, Lindolfo, Aparecida Maria Fontes, Dimas Tadeu Covas, and Arnold I. Caplan. “Mechanisms involved in the therapeutic properties of mesenchymal stem cells.” Cytokine & Growth Factor Reviews 20 (2009): 419-27. Web.
Porada, Christopher D. and Graca Almeida-Porada. “Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery.” Advanced Drug Delivery Reviews 62 (2010): 1156-61. Web.
Shi, Rui-Zhen and Qing-Ping Li. “Improving outcome of transplanted mesenchymal stem cells for ischemic heart disease.” Biochemical and Biophysical Research Communications 376 (2008): 247-50. Web.
United States. Dept. of Health and Human Services. “National Vital Statistics Reports.” cdc.gov US Dept. of Health and Human Services, 20 May 2010. Web. 27 Mar. 2011.

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Essay on Mesenchymal Stem Cells: The Possibilities are Endless

- Mesenchymal stem cells have been used in treatments for years, however the general public was just unaware. Bone marrow transplants are stem cell therapies. Years ago, these transplants were expensive and uncommon, but today they are performed all the time. Conditions such as degenerative disk disease could be effectively treated without the need for long term medications to decrease the chance of host rejection, spinal surgeries, and would greatly improve the quality of life of the individual by continuing mesenchymal stem cell research....   [tags: treatments, bone marrow transplant, therapies]

Better Essays
1665 words (4.8 pages)

Mesenchymal Stem Cells and Curing Disease Essay

- According to the Cord Blood Registry some cells found in cord blood and cord tissue are being used and tested to see if they could improve or even cure certain diseases. Mesenchymal stem cells found in cord blood have been shown to reduce lung injury and symptoms of bronchopulmonary dysplasia in infants. Bronchopulmonary dysplasia or BPD is a lung disease most often seen in premature newborns who need ventilator support or oxygen supplements to treat respiratory illnesses. Recent studies performed on animals suggest that newborn stem cells may be used as treatment....   [tags: genetic engineering and medicine]

Better Essays
701 words (2 pages)

Essay on Study: Mesenchymal Stem Cells (MSC)

- CHAPTER 1 INTRODUCTION Mesenchymal stem cells (MSC), also known as marrow stromal cells, comprise of a rare population of multipotent progenitor cells that possess high self-renewal ability and great potential to differentiate into tissues of mesenchymal lineages including bone, adipose, cartilage, tendon, skeletal muscle (Friedenstein et al. 1974a; Pittenger et al. 1999; Reyes et al. 2001). In fact, MSC have been shown to differentiate into tissue of non-mesenchymal lineages such as cardiac muscle (Arminan et al....   [tags: Medicine]

Better Essays
887 words (2.5 pages)

Mesenchymal Stem Cells and Treatment of Heart Disease Essay

- According to the Department of Health and Human Services, heart disease is the leading cause of death in the United States (1). The medical community is constantly looking for new technologies and discoveries to treat heart disease more effectively. Methods include mechanical based therapies such as artificial heart valves and drug based approaches as with anticoagulant medications. Recently, exciting new discoveries have been made by the scientific community in the development of stem cell based therapies....   [tags: Depeartment of Health, Human Services]

Better Essays
980 words (2.8 pages)

Investigating the Use of Mesenchymal Stem Cells for Neurodegenerative Disorders

- The authors conducted an experiment using in vitro on rats to investigate the use of mesenchymal stem cells (MSCs) for neurodegenerative disorders, including Parkinson’s disease. The authors wanted to investigate the neuroprotective properties of unmodified human MSCs on rat catecholaminergic and serotonergic cell cultures exposed to the damaging effects of nitric oxide. The two contemporary experimental approaches for Parkinson’s disease (PD) research include the implantation of differentiated foetal mesencephalic neurons into the striatum, and the putaminal infusion of glial cell line derived neurotrophic factor (GDNF) (Gill et al., 2003; Piccini et al., 1999)....   [tags: neuronal celll cultures]

Free Essays
699 words (2 pages)

Essay about Glycation and Mesenchymal Stem Cell Function

- New cells are often produced in the body during growth and development. In addition, new cells also develop as the body repairs and remodels its tissues after an injury. These new cells come from mesenchymal stem cells (MSCs), which are considered as multipotent cells. MSCs are found in various parts of the body during growth and development, but in adults, they are present in the bone marrow, where they later differentiate, mature and migrate to become more specialized cells with unique functions....   [tags: msc, stem cells, advanced glycation]

Better Essays
920 words (2.6 pages)

Adult and Embryonic Stem Cells Essay

- We must start at the basic, what are cells. Cells are the basic unit of living things. We all have trillions upon trillions of cells that make up our body. Our body has three main cell types which are: Ectoderm, Mesoderm, and Endoderm. Ectoderm cells are in the skin, hair, eyelids and nerves cells for bones, Mesoderm cells are in muscles, tendons blood vessels and kidney construct the linings of two tubes within the body and Endoderm cells are in digestive tubes and respiratory tube. There are also stem cells.” Stem cells are unspecialized cells that have two defining properties: the ability to differentiate into other cells and the ability to self-regenerate.” (Kochar)There are different ty...   [tags: cells, stem cell, adult, embryo]

Better Essays
597 words (1.7 pages)

A Scientific Explanation of Stem Cells and Stem Cell Research Essay

- In general, a cell can be defined as a stem cell if two basic criteria are met. First, stem cell is capable of self renewal for indefinite period throughout life while maintaining undifferentiated state, i.e., the cell can divide and produce two identical daughter cells and thereby maintains the stem cell pool. Second, stem cell possesses capacity for differentiate into specialised and functional progeny under the right conditions, or given the right signals. It may divide asymmetrically to yield an identical cell and a daughter cell that acquires a particular cell type’s properties, such as morphology, phenotype and functional physiology that classified it belongs to a particular tissue (Bu...   [tags: Science, Stem Cells, Stem Cell Research, ]

Better Essays
610 words (1.7 pages)

Essay on Characteristics, Sources and Function of the Mesenchymal Stem Cell

- 2.2 Mesenchymal Stem Cell (MSC) MSC are initially recognized in the late 1960s by Friendenstein and colleagues, as an adherent, non-phagocytic, fibroblast-like population that could regenerate rudiments of normal bone in vitro and in vivo (Friedenstein et al. 1970; Friedenstein et al. 1974a; Friedenstein et al. 1974b). The group identified a homogenous spindle-shaped adherent cell population when they cultured whole bone marrow (BM) in vitro. Then, this assay was developed into colony forming unit-fibroblast (CFU-F) assay which is the standard method to identify MSC....   [tags: medicine, stem cell]

Better Essays
1012 words (2.9 pages)

Embryonic Stem Cells and Adult Stem Cells Essay

- Embryonic stem cells are a different class of stem cells. ‘Stem cells’ are primitive cells with the capacity to divide and give rise to more identical stem cells or to specialize and form specific cells of somatic tissues. However, two types of stem cell can be distinguished: embryonic stem cells (ES): can only be derived from pre‐implantation embryos and have a proven ability to form cells of all adult tissues (termed ‘pluripotent’). ‘Adult’ stem cells, which are found in a variety of tissues in the fetus and after birth and are, under normal conditions, more specialized, which is revered to as “multipotent.” The embryonic stem cells can assist with tissue replacement and repair....   [tags: genetic engineering and health]

Better Essays
909 words (2.6 pages)