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Lupus reasearch paper
Lupus reasearch paper
Research on lupus essay
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Lupus is a disease in a person body that mistake some of the body’s own tissues for invaders trying to harm the body host, so the body take it cautionary and attacks the tissues. It is considered an autoimmune disease. There are different types of Lupus; the most common one is Systemic Lupus Erythematosus (SLE) which is most common and serious type. Other types such as Cutaneous Lupus Erythematosus aka Discoid Lupus is limited to skin and doesn’t cause the organ damage that happens with SLE. Systemic Lupus Erythematosus while being a visual disease it also has some internal problems. Some internal problems could be such as heart, kidneys, and other vital organs can be damage. Lupus most common symptom is joint pain, butterfly rash, light sensitivity, hair loss, nail changes, Raynaud’s, and fever and fatigue. First common signs of Lupus are joints and muscle pain. It tend to happen to both side of the body in their fingers, hand, wrists, and knees, also they may look inflamed and feel warm when touched. One common recognizable symptom in lupus patients is butterfly-shaped rash across the both cheeks and bridge of the nose. There are other skin problems such as sensitivity to the sun with flaky red spot, or scaly purple rash on different parts of the body including the face, neck, and arms. Many of the lupus patients are unusually sensitive to the sun and other form of ultraviolet light. Another symptom that happens in lupus but come and goes with rest of symptom is hair loss, which means their hair fall out in patches or the hair become thinner across the head. The person’s nails can start to crack or fall off, change in color to blue or reddish spot at the base, which is in the nail bed, in result of inflamed small blood vessels...
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... of where to find more information about lupus online. I personally found a few that I liked and used as my source. The website liked using because it comes from a good reputable source http://www.webmd.com/lupus/guide/understanding-lupus-basics explains what lupus is and what kind there are. It gives a guide and information about lupus from facts to symptoms to diagnosis and test to treatments and care to living to supports and resources. It covers all aspect of what lupus is and what to expect. Another website I liked to use was http://www.lupusresearchinstitute.org/lupus-facts/lupus-diagnosis because it doesn’t speak in medical terms entirely and make it easier to understand what lupus is and what it does to a person’s body. In this site they talk about how no two cases are alike, what are lupus symptoms, what are the treatments, and fact sheets about lupus.
that cause dark red blotches on the skin, usually on the face). Laboratory tests are another consideration of diagnosis. Tests consist of anti-nuclear anti-body (ANA) counts and anti-topoisomerase (an enzyme that reduces super-coiling in DNA by breaking and rejoining one or both strands of DNA). High ANA’s and low anti-topoisomerases are found in patients with Raynaud syndrome. (Desai, 2003) “Patients with circulating autoantibodies, antinuclear antibodies, and anti-Scl 70 antibodies are at (an) increased risk of developing a connective tissue disease. Systemic sclerosis is the connective tissue disease most frequently associated with Raynaud’s phenomenon.” (Bowling, 2003) This syndrome is described as primary Raynaud phenomenon (PRP) if is not associated with another disorder and as secondary Raynaud phenomenon (SRP) if it occurs in association with another disorder.
Lupus is inflammatory disease caused when the immune system attacks its own tissues and organs, and this inflammation affects many different body parts such as the joints, skin, kidneys, blood cells, brain, heart and lungs. Second is the Celiac disease and it is an autoimmune reaction from eating gluten, and it may lead to damage in the small intestine because this disease attacks the villi, the projections that line the small intestine for protection. The last example is Rheumatoid Arthritis, an inflammatory disorder in which affects many joints, mainly in hands and feet, and then causing your joints to painfully swell and possibly cause bone erosion.
Her father's health continued to decline, and it was not until shortly before his death on February 1, 1941 that he was diagnosed with systemic lupus erythematosis, the same disease that would claim Flannery.
The incidence of SLE is 7.6 cases per 100,000 with a prevalence of approximately 68 cases per 100,000 (Bernknopf, Rowley, & Bailey, 2011). It affects women more than men with a 9:1 ratio, and typically affects women of childbearing age (Patel, Fenves, & Colbert, 2012). The mean age of symptom onset was 29 years in the Euro Lupus Project that studied 1000 patients with SLE (“Systemic Lupus Erythematosus”, 2012). Children and older adults are also diagnosed with SLE but at a much lower rate, 8%-15% and 3%-18%, respectively (Arnaud, Mathian, Boddaert, & Amoura, 2010). Patients with ethnic backgrounds have a higher incidence rate with African Americans developing SLE 3-4 times more than Caucasians, unlike drug-induced lupus erythematosus (DILE) which has an equal male to female prevalence yet a higher disease severity in Caucasians (Bernknopf, Rowley, & Bailey, 2011).
Lupus is often hard diagnose because the symptoms mimic other disorders. The most distinctive sign of lupus is a butterfly shaped rash across the cheeks.
...tor(www.lupus.org). “Lupus can be effectively treated, and most people with the disease can lead active and healthy lives”(www.naims.nih.gov). “Although some people with lupus have severe recurrent attacks and are frequently hospitalized, most people with lupus rarely require hospitalization”(www.lupus.org). The patients of lupus who don’t have the type of lupus that affects the organs can live a healthy lifestyle(www.lupus.com).
This condition occurs when the immune system produce abnormal response against substances that are normally present in the body. The immune system becomes incapable in differentiating healthy body tissues and antigens, which results in the destruction of normal body tissues. This is usually characterized by hypersensitivity reaction almost identical to the response in allergic conditions. The cause of the autoimmune disorders are still unknown, however, there is a theory stating that some microorganisms or drugs may have trigger these changes. These can also affect one or multiple organs or tissues. Some of the most commonly affected are blood vessels, joints, muscles, red blood cells, skin, and connective tissues.
Relevance: You might ask why should I care? How does this affect me or what is it exactly? Well the truth is that most people don’t realize they have Lupus. It so difficult to diagnose it is know as the “great imitator” since it resembles a variety of other diseases.
This site was chosen for its popularity and the wealth and breadth of information that are available to anyone with internet access. Tens of millions of people access this website monthly to gain insight and information into their health concerns. WebMD is a resource intended for a wide scope of readers: physicians, nurses, and consumers. The vast majority of users that access WebMD are Caucasian females between the ages of 18-50+ who are college graduates. Literature found on WebMD are: health information, symptom checklist, suggestions for treatment, information on medication, different links to additional information, and a place to store you information for future reference if one desires. All internet users must approach searching for health information through a systematic analytical review process. The evaluation process for a health information Web site should use the same basic principles for evaluation of general Web sites, but since health information can involve ...
Imagine waking up every morning stiff, all your muscles in your body soar, extremely tired and on the verge of exhaustion. The simple task of taking a shower and getting dressed makes you need to lay down for just a few minutes and rest. Your legs ache from a short walk up the stairs last night on your way to bed, as if you ran a marathon in your sleep, and your skin literally hurts to the touch of your clothes as they rub against you. Your blood pressure is up and you can feel the pain emanating from every part of your body. You can’t, for the life of you, find your keys as they hang from the keychain in your hand, because the pain and agitation you are feeling all over has clouded your mind. You are finding it difficult to even concentrate. Never mind the rest of the day ahead of you, that has not even started yet. Now imagine this every day, all day. It almost seems impossible to fathom something of this nature on a daily basis, but that is exactly what most people with fibromyalgia describe as a daily feeling. Some are much worse than that. Fibromyalgia is real, it is pain, and it does exist. Although fibromyalgia awareness has progressed thru advertising there is much more that can, and needs to be done to bring this to the forefront of the medical field and other organizations as a real diagnosis. More research and Government funding is direly needed and demands significant action from our National health agencies and United States Government in the form of grants, research, trials and various drug interaction and testing.
Causes of these disorders include immune-system reactions and the wear and tear of aging, while research indicates that the nervous system may often be equally involved. About one out of seven Americans exhibit some form of arthritis. INFLAMMATORY CONNECTIVE TISSUE DISEASES This varied group of diseases produces inflammation in the connective tissues, particularly in the joints. The signs of inflammation--warmth, redness, swelling, and pain--may be apparent. Microscopic examination of the lesions reveals prominent blood vessels, abnormal accumulations of white blood cells, and varying degrees of wound healing with scarring.
This disease has many symptoms. These symptoms are similar or same to many other illnesses. That is the reason why many doctors get confused when they were researching this disease. There are three stages of symptoms for the disease. In the first stage, the Erythema Migrans, a bull’s eye rash might appear on the bitten area. In the second stage, the Disseminated Lyme Disease, you may experience a fever, sore throat, fatigue, headache, stiff neck, muscle ache, and general malaise. In the third stage, the Chronic Lyme Disease, you may experience aching joints.
It is also estimated that approximately two and half million people are living with the disease... The name multiple sclerosis refers to the scars that are present in the brain and spinal cord is seen on an MRI. An autoimmune disorder is where a person’s immune system mistakes its own white blood cells as invaders and begins to attack itself damaging healthy body tissue. In these types of disorders, the immune system cannot tell the difference between healthy cells and antigens, which are foreign invaders like bacteria and viruses. Because of the damage, it does to the nerve cells; nerve signals can either slow down or stop completely. Inflammation, or the body’s reaction to infection, is what causes this nerve damage to happen. Multiple sclerosis is most commonly seen in the brain, optic nerve, and spinal cord and often leads to physical and cognitive
The symptoms of psoriasis differ from type to type, although inflamed, scaly lesions are present in all five types. The most common form of the disease, plaque psoriasis, is identified by small bumps that begin to grow and become scaly. These lesions flake easily, but removing these patches can cause the tender skin below to bleed. In the Guttate type, small, individual, red drops form. This type does not have as much scaling as plaque psoriasis. The drops usually clear up on their own, but may also reappear as a different form of psoriasis, usually plaque. Inverse psoriasis usually occurs in places where the skin folds, such as the genitals, breasts, armpits or the backs of knees. This type will appear red, yet it will be smooth and dry. Also, no scaling will occur. Pustular psoriasis is a type that's significantly more rare. It is also more painful. In this type, blisters filled with non-infectious pus appear within a few hours and then dry up and peel within another two days. Severe medical risks exist for those who have this particular form of psoriasis, due to its side effects; exhaustion, anemia, weight loss, fever, chills, rapid pulse rate, severe itching and muscle weakness. Even less common than pustular psoriasis is erythrodermic psoriasis. This type is...
One of the most common mysteries in the world is the development of autoimmune diseases. An autoimmune disease is when the immune system, which usually keeps your body healthy thinks that your healthy cells are antigens and attacks them. This is irony right? It is against properties of evolution for an immune system to attack itself causing sickness and possibly death if untreated. There are about 80 different types of autoimmune diseases, which usually have periods of little to no symptoms and worsening symptoms. What particularly creates confusion in the world is the autoimmune disease, inflammatory bowel disease, which affects almost about five million people worldwide.