Liraglutide: Novel Treatment of Type 2 Diabetes Mellitus Essays

Liraglutide: Novel Treatment of Type 2 Diabetes Mellitus Essays

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Substantial advancement has been built in recent years in the development of pharmacological treatment of type 2 diabetes. The most recent developments have been around the incretin hormones. Glucagon-like peptide 1-receptor agonists (GLP-1) have demonstrated efficacy and safety in the treatment of type 2 diabetes. Liraglutide (Victoza) is a GLP-1 receptor agonist that has demonstrated advantages in lower hemoglobin A1c in this class of medications and assisting patients in reducing weight.

Liraglutide: Novel treatment of Type 2 Diabetes Mellitus
Type 2 Diabetes is rapidly becoming the top health concerns in the United States and a major contributor to health care spending and disability. There are an estimated 22.3 million people in the United States diagnosed with diabetes, this represents 7% of our population (American Diabetes Association [ADA], 2013, p. 1038) The American Diabetes Association conducted research in 2012 on the financial impact of diabetes. The authors evaluated 5 years from 2007 through 2012 and discovered the estimated cost of diabetes in 2012 was $245 billion dollars annually as compared to the estimated cost of $174 billion in 2007 (ADA, 2013, p. 1033). These figures are inclusive of care and lost productivity as well as adjusted to inflation. This represents a 41% increase in burden that patients with diabetes and healthcare consumers incur annually (ADA, 2013, p. 1033).

A rise in the amount of expenditures is expected with the increasing prevalence of the disease. The American Diabetes Association estimated that by the year 2050, we expect to see 1 in 3 Americans diagnosed with diabetes. This is a significant increase from the 7% of American currently diagnosed with diabetes (ADA, 2013, p. ...

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... with Type 2 Diabetes Mellitus. Case Reports in Pediatrics, 2013. Retrieved from
Novo Nordisk Inc. (2013). Victoza liraglutide (rDNA origin) injection. Retrieved from
Robinson, M., & Wynne, A. L. (2012). Drugs affecting the endocrine system. In Pharmacotherapeutics for nurse practitioner prescribers (3rd ed., pp. 587-644). Philadelphia, Pa: F.A. Davis.
Ryan, G. J., Foster, K. T., & Jobe, L. J. (2011). Review of the therapeutic uses of liraglutide. Clinical Therapeutics, 33(7), 793-811.
Tierney, K. (2012). Therapeutic choices, and the nurse practitioner’s role, in type 2 diabetes when metformin is no longer enough. Journal of the American Academy of Nurse Practitioners, 24, 234-248. (2014).

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