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cervical cancer development
cervical cancer development
pathogenesis of cervical cancer
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Cervical cancer is the type of cancer that forms in the cervix tissue in women. The cervix is the organ which connects the uterus and the vagina. There are multiple causes for cervical cancer. These causes include: HPV, smoking, immunosuppression, chlamydial infection, diet, oral contraceptives, intrauterine device use, multiple full term pregnancies, young at a first full term pregnancy, poverty, diethylstilbestrol, and a family history of cervical cancer. The most important risk factor for cervical cancer is the Human Papillomavirus, also known as, HPV. HPV is a virus spread through skin-to-skin contact. It is normally sexually transmitted and usually goes away on its own but can sometimes become cancerous. It is such a major risk factor for this type of cancer because it is so commonly and easily transmitted.
Cancer in the cervix can be extremely deadly because the cervix is a major organ of the female body. It forms the lower part of the uterus, or womb and connects the uterus to the vagina, or birth canal. There are two main cells which cover the tissues in the cervix. They are squamous and glandular cells. The common place for these two cells to come in contact with one another is called a transformation zone. Most cervical cancers begin either in the transformation zone or directly in the lining of the cervix. This is what makes cervical cancer the fourth deadliest cancer for women all over the world.
Cervical cancer occurs when normal cells in the cervix undergo pre-cancerous changes that then become cancer. Pre-cancerous changes include: cervical intraepithelial neoplasia, squamous intraepithelial lesion, and dysplasia. All of these pre-cancerous changes can be revealed through a Pap Smear Test. A Pap...
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...th HPV are unaware that they have it which makes it that much more dangerous because that is how it spreads faster. More women in the United States are being diagnosed with cervical cancer each year, but hopefully with cervical cancer awareness that will change.
Works Cited
National Cancer Institute, . N.p.. Web. 30 Mar 2014.
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CDC, . N.p.. Web. 30 Mar 2014. .
American Cancer Society, . N.p.. Web. 30 Mar 2014.
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Harper , D. M.. N.p.. Web. 30 Mar 2014.
genital-warts/hpv-virus-information-about-human-papillomavirus>.
(Attention Getter) The Center for Disease Control reports that 100% of sexually active men and women contract genital HPV
Cervical cancer tissues and normal cervical tissues were collected from 24 newly diagnosed patients with primary cervical cancer, in order to perform the experiments outlined in the paper. Experiments were also performed on the following human cervical carcinoma cell lines: HeLa, SiHa, C33A, and CaSki, which were purchased from a company. The researchers extracted the genomic DNA from the samples collected. The DNA was then bisulfite modified and amplified using PCR. The PCR product was then examined through gel electrophoresis to insure a single band was obtained, and then sequenced by Invitrogen. Methylation-specific PCR was then carried out of the bisulfate-treated DNA. This was done to check the consistency of the ...
What is the human papillomavirus (HPV)? According to the US government’s National Cancer Institute, human papillomaviruses (HPVs) are a collection of more than one hundred viruses, many types having the ability to grow tumors or polyps that are malignant and others benign. Certain of the viruses are capable of forming genital warts. The HPVs that cause the common warts on hands and feet are different from those that cause growth in the throat or genital area (Human Papillomavirus). Professors Joe Cummins and Dr. Mae-Wan Ho inform us that some types are associated with cancer, and are called “high risk” HPVs. Of the more than one hundred types of HPVs, over thirty can be passed on through sexual contact. Most HPV infections occur without any symptoms and go away without treatment over the course of a few years. However, HPV infection sometimes persists for many years, with or without causing detectable cell abnormalities. Infection from “High risk” types of HPV is the main cause of cervical cancer. Pap smears have also led to earlier detection of these infections. Nearly all women who are sexually active will have HPV inf...
There are over 100 types of HPV (Human Papilloma Virus). This virus affects the skin and moist membranes that line the body such as the mouth, throat, fingers, nails, cervix, and anus. Between 30 and 40 of the 100 viruses can affect the genital area; for the most part it causes genital warts. Human Papilloma Virus is one of the most common sexually transmitted diseases In the United States, according to various studies it is estimated that at least 50% of sexually active people will get some type of genital Hpv at some time in their lives. People can get Hpv and have the virus for years, even pass it on to their sex partners without even knowing it that is because the virus often does not show any symptoms. It is a sexually transmitted disease that can cause genital warts and cervical cancer”. (“HPV fact sheet” 2012).
Epithelial tumors are both benign and malignant tumors that develop in the epithelium, the thin layer of cells that cover the ovaries. These tumors usually form on the ovaries of women who have stopped their menstrual cycle. Malignant Epithelial tumors are the most frequent and deadly of all types of ovarian cancers. Together, benign and malignant Epithelial tumors account for 90% of all Ovarian cancer diagnoses.
Breast Cancer is a disease that can sometime lead to ovarian cancer and has caused a lot of women’s death. “About five to ten percent of breast cancer cases are thought to be hereditary, meaning that they result from gene defects called mutations inherited from a parent”. Related Risks early menstruation, oral contraceptives and child bearing 20 percent. (1)An environmental risk is that toxins can damage breast DNA. Over time damaged DNA can lead to cancer. Your risk of developing breast cancer increases as you get older. “1 of 8 breast cancer are found when women are younger than 45. 2 of 3 breast cancer are found in women age 55 years or older 75 percent greater chance”.(1) Breast Cancer can lead Peutz Jeghers syndrome the effects of Peutz Jeghgers is spots on your lips and in their mouths. Women with no children or who had a child after age 30 have slightly higher breast cancer risk. “Screening for breast cancer is early diagnosis increases chance of survival and annual mammogram after age 40”. Women who took Diethylstilbestrol while pregnant could have a slightly higher risk of developing breast cancer. Birth control peals also cause higher risks 40 to 50 percent for breast cancer risk calms down after they have stopped taking them.(1) Using combined hormone therapy after menopause increase the risk of getting breast cancer , it also increase women chances of dying from it. If you are over weight or obese after menopause greatly increase breast cancer risk 20 percent. Drinking alcohol can cause a major effect for you to start developing breast cancer the risk increase the more you drink. Tobacco smoke, Night work, Antiperspirants, Bras and Induced abortion. Breast cancer takes a lot of toll on women and men of all races and...
...tion, nearly 80% of cases occur in low-income countries, where cervical cancer is the most common cancer in women. Of course by taking the vaccine one cannot eliminate the cancer since it only targets four strains of HPV but it will surely reduce those numbers greatly, and isn’t this what we want in the end?
All families should get their children vaccinated against the most common STD in America, the Human papilloma virus (HPV). As health care professionals it is essential to educate parents and adolescents about the HPV virus which can cause genital warts along with many varieties of cancers including cervical, penile and throat cancer. The vaccine will guard against four strains of the virus. Two of these strains are known to cause 70% of cervical cancer cases and the other two cause 90% of genital warts (Kara Newby, 2009). Another reason to receive the HPV vaccine is to promote sexual and reproductive health education. Two of the biggest arguments against the HPV vaccine are the high cost and that some parents feel it will make their teenagers feel invisible and may engage in more risky sexual behaviors if vaccinated.
Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell. Cells become cancer cells because of DNA (deoxyribonucleic acid) damage. DNA is in every cell and it directs all the cell’s actions. In a normal cell, when DNA gets damaged the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, and the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same abnormal DNA as the first cell does.
...nd can cause a variety of serious health problems if not treated. Health complications that are produced by HPV include genital warts, “cervical cancer” and other serious cancers such vulvar, vaginal, uterine, and ovarian all of which are characteristics of gynecological cancers. Starting with a young target audience will allow young women to be conscious and aware of what can lead to cancer. The saying “one thing leads to another” in this aspect is true, knowing details and what triggers cancer is what all women should to know. Based on the concept of this campaign I have a better understanding of gynecological cancer, the five main types of cancer and the risk factors. Through this campaign I am also able to deliver the message to female family members ensuring every woman in my family are aware of gynecological cancer given through the Inside Knowledge campaign.
Cancer has become the one of the most feared things for human beings. The various type of cancer have been discovered and there are still a lot of it that undiscoverable. Cancer is a complex disease that have a group of disease. The cancer itself cannot be describe by words. The causes of this cancer is still not being able to be discovered fully. There are only minor factor that can lead to this disease. The carcinogens are believed to be one of the causes that lead to cancer such as asbestos, radon gas, tobacco, PVC and much more from our chemical industries. The environment especially near to the industrial that produce chemical waste can be one of the causes lead to cancer. Cancer also have relation with our age, lifestyle, and diet and also can be genetically inherited. It is believed that older people have higher tendency to get cancer than younger people. Our lifestyle and diet also plays a role causing a cancer by our daily life routine. Smoking tobacco and eating unconsciously (still in research) can also increase the possibility to get cancer especially lung cancer that cause by smoking tobacco. There are several cases, cancer were inherited from their parents. Various type of viruses such as HIV, HPV, EBV and many more virus has a high capabilities to increase the chance a patient to get a cancer because these viruses lower their body immunity to disease.
Ovarian Cancer is a disease of uncontrollably dividing cancer cells in the ovary. Being one of the most devastating diseases to have, along with a limited number of treatment opportunities, it may feel like there has been a time stamp put on your life. With that said, there are four different types of ovarian cancer: epithelial tumors, germ cell carcinoma tumors, stromal carcinoma tumors, and small cell carcinoma of the ovary. Epithelium cancer is the fourth leading cause of death in women in the United States, killing approximately 140,000 women yearly.
Human Papillomavirus is a common viral infection that has emerged as an important risk factor. Anyone who is sexually active is at risk for getting this disease; although there is a vaccine to prevent it. Once someone has HPV they are more at risk for genital warts and Cervical cancer (CDC). It can years for the symptoms to ...
Cancer is a disease that affects human somatic cells. It causes the cells to divide uncontrollably and form masses known as tumors. There are two different types of cancer tumors. Some tumors are benign and other tumors are malignant. Benign tumors look similar to the tissues that they came from and develop slowly. The tumor remains in the same area that the tumor originated in. Malignant tumors are formed from cells that do not resemble the tissue that they came from. They vary in shape and size. This enables pieces of the tumor to break off and spread to other places in the body. Over the past few decades cancer has become a very prominent disease. There are many different types of cancer and many different causes for the the disease. Most cancers are because of a genetic mutation. The most common type occur when a cell is dividing. Proto-oncogenes, which are alleles in a normal cells, mutate to form oncogenes. These oncogenes cause cancer because they do not allow the cells to self destruct or become epistatic. There have been several research projects which have been testing epistatis.
Uterine cancer is an important women health problem developing rapidly, killing over 200,000 women each year. No one has discovered the actual cause, but there is a leading factor that has great suspicions to what is causing this cancer to grow rapidly.