How Maternal Infections Can Cause Cerebral Palsy Essay

How Maternal Infections Can Cause Cerebral Palsy Essay

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As mentioned earlier in this review that maternal infections can cause cerebral palsy. Maternal infection could be viral or bacterial infections. For instance, Cytomegalovirus (CMV) can cross the placenta and damaged the white matter for the offspring. McMichael et al (2012) conducted a study to investigate the possible causes of cerebral palsy during gestation. The aim of this study was to indicate the involvement of CMV and Epstein - Barr virus (EBV) with CP. These viruses can cross the placenta and blood-brain barrier then damaged the fetus brain and lead to neural lesions (McMichael et al., 2012). Furthermore, researchers tested different types of viruses such as human simplex viruses (HSV 1&2), human herpes viruses (HHV 6, 7 and 8), varicella zoster virus (VZV) and parvovirus B19. The researchers then stated that intrauterine infections have remarkable sign included fever during labor. HSV and CMV can harm the newborn by causing hear loss, brain damage that include CP, seizure and mental retardation (McMichael et al., 2012).
A retrospective case-control study was implemented in this research. In addition, newborn screening cards (NBSC), polymerase chain reaction (PCR) were used in the study. In addition, X2 test was introduced in this research to compare the viral occurrences between control and CP cases. The experiment started by dividing the participants into two groups: test and control groups. The test group included children with cerebral palsy while the control group included adolescent and children which their ages varied from five to eighteenth years old. Consent forms were signed by the parents of the participants. After signing the forms, the scientists start collecting the samples using a stainless steel puncher ...

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...The limitations of this research that small sample size with no history of falls and no reductions in mobility. Additionally, the finding can help individuals with cognitive impairment at level IV and V of gross motor function classification system. In conclusion, the HRQOL in adults with CP was affected negatively due to falling history. In other words, age and sex can be correlated to the health status in the individuals with CP. Thus, additional studies are needed to clarify the relationship between HRQOL, mobility diminish and falls.
All the previous studies used data collection and comparison technique. Though these research studies answered some questions about cerebral palsy, a few questions have not been answers yet such as: involving of Neisseria meningitides and Haemophilus influenzae subtype b cerebral palsy and reducing the side effect of cerebral palsy.

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