Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.
Hemophilia A, the most occurring form of this disease, is also known as factor VIII deficiency. It is mainly an inherited condition, which occurs when the protein that is needed to form the blood clots is no longer there. In about 30% of the cases, there is no family history of knowledge of the disorder and the condition, hemophilia, is the result of a ‘spontaneous gene mutation’. ‘Roughly one in every 5,000 males born in the United States has hemophilia and can happen to people of all races and economic groups equally.’ (www.whatishemophilia.com)
Small cuts are usually not an issue, but if a more traumatic event occurs, serious problems could arise. There are 3 different levels of hemophilia, mild, moderate and severe. People who have mild hemophilia have between 6% and 49% of the normal clotting factor. Those who suffer from moderate hemophilia have roughly 1& to 5% of the clotting factor and make up about 15% of society that suffers from hemophilia. Those who have severe hemophilia have less than 1% of the clotting factor and make up about 60% of...
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HEMOPHILIA 101. (n.d.). Hemophilia Village. Retrieved May 8, 2014, from http://www.hemophiliavillage.com/hemophilia-overview/what-is-hemophilia
Causes of Hemophilia - Hemophilia Federation of America. (n.d.). Hemophilia Federation of America Causes of Hemophilia Comments. Retrieved May 9, 2014, from http://www.hemophiliafed.org/bleeding-disorders/hemophilia/causes/
Hemophilia - Nu Factor. (n.d.). Retrieved from http://www.nufactor.com/DS_Hemophilia.aspx
Treatment And Effect Of Hemophilia Biology Essay. (n.d.). Retrieved from http://www.ukessays.com/essays/biology/treatment-and-effect-of-hemophilia-biology-essay.php
Life, love, and bleeding hearts at hemophilia camp. (n.d.). Retrieved from http://www.pchrd.dost.gov.ph/index.php/2012-05-23-07-46-36/2012-05-24-00-03-06/2257-life-love-and-bleeding-hearts-at-hemophilia-camp
Originally thought to be an obscure illness, it was later identified as the most common genetic disorder for those with a Western European background. However, due to its low penetrance rate, only one out of two hundred are said to have the condition. Hemochromatosis is treated by the practice of bloodletting. It is one of the oldest treatments recorded in history, with its earliest records dating as far back as 3000 years ago in ancient Egypt. Routinely bleeding is beneficial as it not only reduces the iron in the bloodstream, but also combats issues such as heart disease and high blood
• Hemolytic disease of the newborn. Hemolytic disease happens when a mother 's disease fighting system (immune system) attacks her baby 's red blood cells. Proteins (antibodies) in the mother’s blood destroy the baby 's red blood cells. Two conditions can cause hemolytic disease:
About eighty percent of all cases of hemophilia have an identifiable family history of the disease; in other instances, it may be attributable to a spontaneous mutation. Researchers recently discovered that the spontaneous mutation of the factor VIII gene in two children was due to the attachment of a foreign "jumping gene" that disrupted the blood-clotting ability of the factor VIII gene. Inheritance is controlled by a recessive sex-linked factor carried by the mother on the X chromosome. A probability of one in two exists that each boy born to a normal male and a carrier female will be hemophiliac and the same chance that each girl of this union will be a carrier.
"Causes Of The Civil War." History Net: Where History Comes Alive. 12 Dec. 2013 .
Haemophilia is used to describe a collection of hereditary genetic diseases that affect a mammal’s body’s capability to control thrombogenesis. Thrombogenesis is the way in which blood clots which is an important role in haemostasis. Two common forms of haemophilia are A and B. (1) Someone with A (otherwise known as classic haemophilia), clotting factor VIII is does not exist enough or is entirely absent. A person with haemophilia B (otherwise known as Christmas disease), clotting factor does not exist enough or is also entirely absent. Those with the disorder do not bleed a lot they just simply bleed for a longer period of time. All people with haemophilia A or B are born with the disorder as it is a hereditary disorder and passed down through generations very few cases of haemophilia are not genetic and are therefore rendered a spontaneous gene mutation which is then passed down.
Thalassemia is an inherited blood disorder characterized by low amounts of hemoglobin and a low count of erythrocytes in the body. Thalassemia is caused by mutations in the deoxyribonucleic acid of cells, which makes hemoglobin. The mutations are passed from parent to child. The mutations vary depending on the type of Thalassemia inherited. The variation in the mutation occurs from the number of gene mutations, which are inherited, as well as mutation within the hemoglobin molecule. Clinical manifestations are diverse ranging from asymptomatic, to those who are carriers of the thalassemia, which may have mild symptoms, there also people who posses the trait, who may have severe symptoms which lead to death.
Tsar Nicholas II and his Tsarina, Empress Alexandra, had only one son, Tsarevich Alexei. However, Alexei had inherited from his great-grandmother Queen Victoria the life-threatening genetic disease hemophilia B, a sex-linked genetic disease on the X chromosome that caused a condition of deficiency in blood-clotting and excessive bleeding, symptoms that usually remain hidden unless contracted by a male (Fuhrmann 37; King 28). To Nicholas II, it was imperative that he have a son to succeed him to secure the throne. Alexei was Nicholas’s sole male heir, giving Nicholas the incentive to protect his son at all costs. Without a scientific cure for the genetic disease, Alexandra turned to religion, namely Grigori Rasputin, a poor uneducated Siberian peasant to protect her son.
Hemophilia is a serious genetic condition caused by a coagulation factor that causes a mutation in the f8 and f8 gene. Hemophilia can be treated but not cured. Further studies are currently being done today. Living with hemophilia can be very difficult .physical activity is not recommended for individuals living with this condition. Also surgery is highly dangerous because of the excessive bleeding. In society we have set backs but we have to learn to deal with them.
Martin, B. (2007). Causes of Attention Deficit Disorder (ADHD). Psych Central. Retrieved on December 3, 2013, from http://psychcentral.com/lib/causes-of-attention-deficit-disorder-adhd/0001202
Abraham, R.A. (2015, February 25). “Causes of bipolar disorder”. webmd.com Web. 28 June 2015. http://www.webmd.com/bipolar-disorder/guide/bipolar-disorder-causes
"Child Abuse Symptoms, Causes, Treatment - Who Abuses Children? - OnHealth." Onhealth. Web. 27 Mar. 2014.
Rodak, B. F., Fritsma, g. A., & Doig, K. (2007). Hematology: Clinical Principles and applications. St. louis: Saunders Elsevier.
Urinary Tract Infections (UTIs) Symptoms, Causes, Treatment - What is a urinary tract infection (UTI)? - MedicineNet. (n.d.). Retrieved March 22, 2016, from http://www.medicinenet.com/urinary_tract_infection/page2.htm
Causes & Types of Teen Rebellion. (n.d.). Everyday Life. Retrieved December 1, 2013, from http://everydaylife.globalpost.com/causes-types-teen-rebellion-20286.html
Thalassemia is a blood disorder transferred through families. It occurs when the body makes less hemoglobin than needed or an unusual form of hemoglobin. Hemoglobin is the protein in red blood cells that carry oxygen. The disorder makes an excessive amount of destruction of red blood cells. This eventually leads to anemia.