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patho-physiology of acute renal failure
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Organ Failure OWE
Kidneys are one of the most vital organs in the human body that carry out important functions through removing and filtering waste products from blood present in the body. Kidneys also work in the body to balance regulate blood pressure, blood cell production and also balances water and minerals in the body, like salt and electrolytes in the blood streams (“Kidney Failure”). When blood is filtered by the kidneys in the body, urine is produced and this urine is collected in the pelvis of the kidney which is also connected to the bladder in which the urine is disposed through. Figure one shows the anatomy of the kidneys in the body hence shows how they are connected to the bladder.
Fig 1
Diagram of Kidneys in the human body. Digital image from web. The Kidneys (human anatomy) : Picture, function, definition, and conditions. WebMD, accessed on Saturday 5th April 2014. http://img.webmd.com/dtmcms/live/webmd/consumer_assets/site_images/articles/image_article_collections/anatomy_pages/Kidney2.jpg Kidney failure occurs when waste products build-up in the body due to the kidney being unable to filter out the waste products properly. Human waste is then accumulating in the blood and the body, and when the concentration of waste present in the bloodstream becomes too high, kidney failure is then affected by harmful symptoms usually known as Uraemia. Kidney failure can be classified into two different groups, Acute Kidney Injury
(AKI) or Chronic Kidney Disease (CKD). AKI is known as the rapid loss of kidney functions and can generally be identified by low production of urine. CKD develops at a slower rate and show few or almost no symptoms at first. Kidney damage and loss of function lasting more than 3 months can be...
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.... http://www.webmd.com/a-to-z-guides/acute-renal-failure-topic-overview Accessed on Saturday 5th April 2014
“Kidney Transplants” Kidney Transplant facts and information http://www.mayoclinic.org/tests-procedures/kidney-transplant/basics/definition/prc-20014007 Accessed on Saturday 5th April 2014
“How Kidney Procedures Go” Procedure of Kidney transplant http://www.nhs.uk/Conditions/Kidney-transplant/Pages/How-is-it-performed.aspx Accessed on Saturday 5th April 2014
“Kidneys-How it’s performed” How it is performed (surgical viewpoint)? http://my.clevelandclinic.org/services/kidney_transplantation/hic_kidney_transplant_procedure.aspx Accessed on Saturday 5th April 2014
“Kidney Transplant Advantages & Disadvantages” Advantages and Disadvantages. http://www.cpmc.org/advanced/kidney/patients/topics/benefits_transplant.html Accessed on Saturday 5th April 2014
The kidneys are located in the posterior section of the retroperitoneal cavity and are small, dark red kidney-bean shaped organs in the lower part of the rib cage (Marieb, The Urinary System, 2015). They are undervalued organs considering how essential they are for the body’s ability to maintain homeostasis. The kidneys filter about 120-150 quarts of blood to produce about 1-2 quarts of urine each day (NIH, 2014). Blood initially enters the kidneys through the renal artery. It then flows into the segmental artery before moving into the interlobar artery. From the interlobar artery the filtrate enters the arcuate artery before branching into the cortical radiate artery, which feeds into the afferent arteriole, before passing into the glomerulus where it begins to filter out waste. The filtered waste is then collected by renal tubule. The tubules drain to collecting ducts and all of these components together makes up a small unit called a nephron. Each kidney has over a million nephrons (Marieb, Blood Supply/ Nephrons, 2015). They filter out wastes that run through different body systems via blood; the majority of that waste is nitrogenous wastes, toxins, excess fluids, electrolytes, and drugs. These waste products are eliminated as urine. While waste are removed vital enzymes, hormones, and water are returned
Kidneys have important roles in maintaining health and making our lives easier everyday. It is located near the middle of your back, just below the rib cage. Functions of the kidneys include extracting wastes from the blood and balancing body fluids from the urine. Most of kidney diseases attack the nephrons, which is the functional units of the kidney. This damages causes kidney malfunctions for example, medicines, genetic problems and injuries.
What diagnostic exams would be used to diagnose acute renal failure? How do these tests change as renal failure progresses through its 3 stages? Discuss, compare and contrast the 3 stages.
1 in 3 Americans Adults are currently at risk for developing kidney disease. What is acute renal failure, when your kidneys functions all of a sudden stop working and your kidneys are the body’s filter which remove waste products and help balance water, salts and minerals especially electrolytes in your blood when your kidneys stop working you end up building all the products in your body that need to be filtered and eliminated. The pathophysiology of Acute Renal Failure are due to three main causes Pre-renal, Intra-renal, and Post renal. Pre-renal is a sudden drop in blood pressure or interruption of blood flow to the kidneys from illness or sever injury. Intra-renal is direct damage to the kidneys by inflammation of drugs, infection, toxins or reduced blood supply. Post-renal is a sudden obstruction of urine flow because of enlarged prostate bladder tumor, kidney stones, or injury.
Kidneys, Ureters, Urinary Bladder, and Urethra are the four main organs that make up the Urinary System. The Kidneys filter blood and produce urine. The Ureters function is to transfer urine to the urinary bladder from the kidneys. The Urinary Bladder is responsible for gathering and hold urine until it has to be excreted out the body.The Urethra is responsible for transporting and excreting urine from the urinary bladder to the outside of the
The urinary tract consists of two kidneys, to ureters, urethra, and the urinary bladder. The urinary system works to remove waste from the body, maintain homeostasis of water, blood pressure, and regulate the body’s pH levels. The kidneys regulate several important internal conditions by excreting substances out into the body. After urine has been produced in the kidneys it is then transported to the urinary bladder via the ureters. The urinary bladder then holds the urine until the body is ready for excretion through the urethra.
(5) NIH Publication No. 03–4241. Your Kidneys and How They Work. National Kidney and Urologic Diseases Information Clearinghouse, 2003. http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/
Introductions Throughout our body we have many majors organs and each organ has a major function on our body. One of the major organs of the urinary system is the kidneys. We have 2 reddish brown, fist size, bean shaped kidneys in our body located on the anterior side by the lower edge of the ribs on either side of the spinal cord. The major function of your kidneys is to filter the blood to remove waste products, helps balance water, salt, electrolytes and forms urine. There must be an adequate blood supply in order for the kidneys to function properly. When your kidneys suddenly shut down and stop working it’s called acute renal failure. Acute renal failure is the most common leading deaths in hospitals today.
the kidney’s ability to remove waste and excess fluids from the body. The damaged may
The kidneys are bean shaped organs. They are a brownish-purplish sort of color. The outside of the kidneys are very tough, but smooth. This is described as a fibrous tunic. The outer part has millions of nephrons which are the basic unit of the kidney. The kidney is divided into two layers. The outer cortex and the medulla. When the outer cortex is stripped off you then get the medulla. The inside you have a thick mesh of muscular fibers. This is also smooth, and very even. It is very red in color, unlike the outside which is of brownish-purplish coloring. It is more red in color because it has tiny blood vessels. The kidneys are located in the posterior part of the abdomen, on both sides of the vertebral column. An easier way to say that would be right below the ribs towards the middle of your back. The right kidney is usually lower in location than the left kidney because of where the liver is. Each kidney is about 11cm long, 6cm wide, and 2.5 cm thick. The kidneys remove urea from the blood through a blood filtering unit called a nephron. There are more than 2 million nephrons in each kidney. The nephron is part of the homeostatic mechanism of your body. That mechanism maintains your water-salt balance, and it also regulates the amount of urea in your body. The blood enters the kidney through the bowmans capsule under pressure. This just surrounds the tuft of capillaries which is the glomerulus. The liquid just flows through the glomerulus under pressure. The pressure pushes the liquid out and keeps in the larger cells. This is filtration, because the glomerulus is taking the nutrients in and getting rid of the waste. After the filtering ...
The urinary system is composed of the kidneys, the ureters, the urinary bladder, and the urethra ("Urinary System", n.d.). These organs and tubes shape what is called the urinary tract, the body’s drainage system for removing urine from the kidneys, storing the urine, and then expelling it during urination ("Urinary System", n.d.). The first part of the urinary system is the kidneys. The kidneys are a pair of bean-shaped organs located in the upper abdominal cavity against the back muscles ("Urinary System", n.d.). The kidneys are responsible for filtering the blood to remove waste and chemicals to produce urine ("Urinary System", n.d.). Blood is carried through the renal arteries to the kidneys where they are filtered by nephrons - tiny filtering units in both kidneys that remove harmful substances and waste from the blood (Durani, 2015). The toxins and waste sifted by these nephrons are blended with water to produce urine (Durani, 2015). On average, the kidneys will filter 120 to 150 quarts of blood a day to produce about 1 to 2 quarts of urine ("The Urinary Tract & How It Works", 2014). The next
Kidneys clear waste products from our blood. They play a role in controlling the body’s level of water and chemicals, and produce essential hormones. (Australian Institute of Health and Welfare, 2013)
Healthy kidneys clean the blood by filtering out extra water and wastes. They also make hormones that keep your bones strong and blood healthy. When both of your kidneys fail, your body holds fluid. Your blood pressure rises. Harmful wastes build up in your body. Your body doesn't make enough red blood cells. When this happens, you need treatment to replace the work of your failed kidneys.
Kidney Diseases : Kidney help the body by removing waste and extra water in the body and keeping blood clean and chemically
Kidneys are filter organs present in vertebrates which help in removing water soluble wastes from the blood. A normal human body possesses two kidneys which are bean shaped and weigh around 150 grams each. Kidneys function as the waste disposal system of our body. Every day kidneys are processing around 200 litres of filtrate while absorbing large amount of it and producing around 1 to 2 litres of waste. Kidneys allow reabsorption of molecules from this filtrate into the blood. Thereafter these molecules are transferred to urinary bladder and then expelled from the body as urine. Kidneys are also producing hormones like erythropoietin, vitamin D and enzyme renin. Kidneys perform homeostatic functions which includes regulating