Gene Therapy to Prevent Disease Essay

Gene Therapy to Prevent Disease Essay

Length: 1671 words (4.8 double-spaced pages)

Rating: Powerful Essays

Open Document

Essay Preview

Gene therapy is an innovative approach to treating and preventing disease (for example: cancer, viral infections, etc.), by replacing a mutated gene with a healthy copy of that same gene. The mere concept of gene therapy was first introduced to the scientific community in the early 1960’s and 1970’s, however it is still in its infancy1 as a medical practice. This technique is experimental and is not yet widely practiced yet in modern medicine because its efficacy is still being thoroughly worked on and investigated.
In the 1960’s and 1970’s, gene therapy was just a concept; an idea fostered by science fiction. However, in 1972, Theodore Friedmann and Richard Roblin published a paper proposing the idea that “ ‘good DNA’ could be used to replace defective DNA in people with genetic disorders”1. This approach to treating diseases was investigated and studied, and administered for the first time on a toddler (a four-year-old child) with a severe congenital immune deficiency (ADA deficiency) on September 14, 1990 by W. French Anderson and his colleagues.2 The patient’s disease, adenosine deaminase deficiency (ADA deficiency), is a congenital or inherited disorder that damages the immune system, leaves it vulnerable to the acquisition of other diseases, and eventually develops into severe combined immunodeficiency (SCID) which causes the individual to lack virtually all immune protection from bacteria or viruses. To help this patient, Anderson extracted white blood cells from the patient’s bone marrow and reinserted the normal genes which produce adenosine deaminase into her system.3 The procedure was successful, and as a result, 300 more clinical gene therapy trials were performed over the next ten years.2
Gene therapy has evolved ...

... middle of paper ...

...ene Therapy and Germ Line Gene Therapy. Retrieved from

6: Williamson, R., & Kampmann, B. (1993). Retrieved from

7: University of Utah (2004). Exploring Gene Therapy. Retrieved from

8: Bushelle, E., Hertz, E., Hubbard, D., Saylor, K., & Slyker, A. (2003). Technology of Gene Therapy:. Retrieved from

9: Balan, S. (2011). Types Of Gene Therapy - Advantages And Disadvantages of Gene Therapy. Retrieved from

10: University of Utah (2014). Gene Therapy Successes. Retrieved from

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Gene Therapy : A Controversial Issue Essay

- Gene therapy has been a very controversial issue since its origin in 1990 when A four-year old girl became the first gene therapy patient. She has adenosine deaminase (ADA) deficiency, a genetic disease which leaves her defenseless against infections. Gene therapy involves substituting normal genes for the genes associated with a disease or disorder otherwise altering a person’s genetic makeup. Each gene has a specific code for what it is supposed to do. So, on top of our genome, we have a complex epigenome....   [tags: Genetics, Gene, DNA, Genome]

Powerful Essays
784 words (2.2 pages)

The Biological Code Of Gene Therapy Essay

- Who doesn’t look in the mirror and question why they aren’t taller. Why their hair is brown and not blonde or the colour they desire, or why they can’t run as fast as the boy next door. We always think how amazing it would be to be able to decide our traits; to be able to change and alter the biological process which gives us our genetic height and athletic ability, to be able to choose and change to what we want ourselves to look like and achieve. But what would the public say if there actually was a process which allowed us to do so and biologically enhance our human traits....   [tags: Genetics, Gene, DNA, Evolution]

Powerful Essays
1005 words (2.9 pages)

Essay on Genetic Disorders And Gene Therapy

- There are thousands of children born with genetic disorders each year in every part of the world, but unfortunately none of them can be cured, yet. A genetic disorder is a disease that an individual is born with where there is a deformity in his or her DNA. However, with future advancements in medicine, there is a chance that doctors and scientists may be able to detect these gene abnormalities before a child is conceived. What this entails is scanning an egg and/or the sperm of two possible parents and then altering their genetic make-up to eradicate the potential abnormality, or as it is called today, germline gene therapy....   [tags: Genetics, DNA, Gene, Genetic disorder]

Powerful Essays
2022 words (5.8 pages)

Preventing Genetic Disorders With Gene-therapy Essay

- Ten years ago researchers from the U.S., Britain, France, Germany, Japan and China sat down and began developing the most important map ever made. Instead of roads and landmarks, this was a map of letters. It was “a rough map of the 3 billion letters of genetic instructions that make us who [we] are” (“First”). On Monday, 26 June 2000, the researchers announced that the map of the human genome was complete. On 26 June 2000 the news of the completion of the human genome was on all the major news wires, televisions and newspapers....   [tags: Gene Therapy Essays]

Powerful Essays
2229 words (6.4 pages)

The Future Of Germ Line Gene Therapy Essay

- Imagine this: You just got back from your germ-line procedure to alter your genes for brown hair and green eyes because you didn 't want to pass them on to your children. Everyone is saying that having brown hair and green eyes is unattractive now and they 're unwanted traits for future generations. Three months later the “fad” changes and people begin to think that having green eyes won 't be so bad after all and that they 're actually unique. Now you 're left with passing on the Version 1.0 gene pool to your children while everyone else who waited could have children with green eyes....   [tags: Genetics, Gene, DNA, Francis Crick]

Powerful Essays
2252 words (6.4 pages)

Gene Therapy Saves Lives Essay

- Gene Therapy Saves Lives       Tim was diagnosed with a rare and deadly disease this morning. He is only five years old with the rest of his life ahead of him. It isn't his fault that he received this disease or even his parents'. This disease comes out in anyone's body that has a defected gene. The disease has made Tim live in a sanitized bubble the last year because of the fear that he might catch any common bug and die. He has severe combined immunodeficiency, or SCID. The disease lacks a gene in charge of the body's immune system called adenosine deaminase....   [tags: Argumentative Persuasive Argument Essays]

Powerful Essays
1964 words (5.6 pages)

Human Gene Therapy Essay

- Human Gene Therapy Image what it would be like if doctors could cure Huntington's disease, muscular dystrophy, or even hemophilia. Could this be possible. With gene therapy this all could be reality in the near future. Gene therapy is a potential approach to the treatment of genetic disorders in humans. This is a technique where the absent or faulty gene is replaced by a working gene, so the body can make the correct enzyme or protein and consequently eliminate the root cause of the disease (BIO, 1990)....   [tags: Science Genetics Essays]

Powerful Essays
1776 words (5.1 pages)

Essay on Human Gene Therapy

- Human Gene Therapy Each of us carry about half a dozen defective genes. Most of us do not suffer any harmful effects from our defective genes because we carry two copies of nearly all genes, one derived from our mother and the other from our father. Because in the majority of cases, the potentially harmful gene is recessive, its normal counterpart will carry out all the tasks assigned to both. Only if we inherit from our parents two copies of the same recessive gene will a disease develop. Every year a considerable number of children are born with a genetic disease, a disease that occurs because each of their parents carries a defect in the same gene (Rigby 1995)....   [tags: Science Genetics Papers]

Free Essays
2540 words (7.3 pages)

Gene Therapy Essay example

- Gene Therapy Gene therapy is a powerful new technology that has the ability to change the way medicine is practiced in the future. The potential of gene therapy offers great hope for cure and alleviation of suffering from genetic disorders that now plague numerous people. Within this past decade, much research has been conducted to learn about the aspects of gene therapy, but there is still much to learn before it is an effective medical treatment. Despite failures to prove any clinical efficacy, many experts of gene therapy predict that the first clinical success will occur in the near future....   [tags: Genetics Ethics Treatment Disorders Papers]

Powerful Essays
4676 words (13.4 pages)

gene therapy Essay

- Gene Therapy is hope or disaster for Human Being. ◊Introduction DNA determines the placement of amino acids according to DNA sequences. A specific chain of amino acids composes a specific protein that plays the essential functions in the bodies. The defect of the gene, however, results in producing wrong protein; as a result, some part of the bodies abnormally works compared to that of other normal bodies. This is called ?gGenetic Disorder?h. The scientists studied about genetic disorder and suggested an alternative for genetic disorder called ?gGene Therapy?h....   [tags: essays research papers]

Free Essays
1201 words (3.4 pages)