Gene Therapy Essay

Gene Therapy Essay

Length: 1053 words (3 double-spaced pages)

Rating: Strong Essays

Open Document

Essay Preview

In September 14, 1990, a four-year-old girl named Ashanti De Silva with ADA (an inherited immune system disease) sat quietly at the National Institutes of Health in the United State, and she was the first person to get a new but controversial called Gene Therapy. The operation was only a temporary success when the case of “Jesse Gelsinger” happened. Gene Therapy is a remedy that introduces genes to target cells and replaces defective genes. It can cure diseases which cannot be cured by traditional medicines. Although Gene Therapy gives someone who is born with a genetic disease or who suffers cancer a permanent chance of being cured, it is high-risk and sometimes unethical because the failure rate is extremely high and some ethical issues like how “good” and “bad” uses of gene therapy can be distinguished have not reach a satisfying answer.
Gene Therapy gives people who suffer from genetic diseases a chance to lead a normal life. Dangerous diseases, such as AIDS, SCID, Thalassemia and ADA can be cured successfully. In September 5, 2006, two people with advanced melanoma received Gene Therapy and they got recovery soon. That is a breakthrough in cancer gene therapy. Gene Therapy uses patients own cells to cure diseases, and, therefore, no rejection to their bodies. Furthermore, patients could get permanent cure from Gene Therapy without recurrence.
Despite Gene Therapy seems magical, it is high-risk. Few people got benefits from it, and it has a low rate of success. Prior to the human trial, Batshaw and Wilson had done experiment on animals to ensure the safety. Over 20 experiments have been done on mice but only 12 of them survived at last (Sophia, M. and Kolehmainen, J.D., 2000). More seriously, complicating diseases, which ...


... middle of paper ...


...iotech/kolehmainen.html#primer [Accessed July 7, 2011]

Reuters. (2009) Gene therapy edges towards commercial reality, Genetics and Society [online] Available at: http://www.geneticsandsociety.org/article.php?id=4691 [Accessed July 7, 2011]


Tweet. Gene Therapy - Ethical Considerations in Gene Therapy, Science. J-rank [online]. Available at: http://science.jrank.org/pages/2963/Gene-Therapy-Ethical-considerations-in-gene-therapy.html [Accessed July 7, 2011]



Waters, R. Gene Therapy Takes a Turn for the Better, Business Week[online] Available at:
http://www.businessweek.com/magazine/content/10_18/b4176027902498.htm [Accessed July 7, 2011]

Weiss, R. (1998), Engineering the Unborn: Another in a series of occasional articles [online]. Available at:

http://www.washingtonpost.com/wp-srv/national/science/genetherapy/unborn.htm[Accessed August 18, 2011]

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Gene Therapy Using Viral Vectors Essay

- Currently, gene therapies implemented in clinical situations usually employ a viral vector to incorporate a functional copy of the complete gene. However, severe complications due to oncogene combination often occur, leading to an increased use of endonucleases such as zinc finger nucleases, transcription activator-like effector nucleases, and CRISPR/Cas9 to treat the genetic mutation in IL2RG which cause XSCID. Techniques such as these introduce a double-stranded break in the DNA to instigate homology-directed repair mechanisms....   [tags: DNA, Gene, Genetics, Gene therapy]

Strong Essays
955 words (2.7 pages)

Mechanism of Transfer in Gene Therapy Essay examples

- Mechanism of Transfer in Gene Therapy Abstract: Gene therapy is the transfer of “normal” genes into the body to replace defective or undesired genes. The transfer may be in somatic or germline cells and may take place in vivo or in vitro. The DNA may be inserted in a retrovirus, adenovirus, adeno-associated virus, herpes simplex virus, or liposome, or it may be naked DNA. The vector travels to a target cell and inserts the gene, which goes to the host cell’s nucleus and may integrate into the genome....   [tags: Gene Therapy]

Strong Essays
2072 words (5.9 pages)

Moral and Ethical Issues in Gene Therapy Essay

- Due to the fact that the field of biotechnology is very serious and potentially dangerous, rules must be set down in order to keep the research in check. The high risk research of genetic therapy needs guidelines that have to be followed in order to keep the study just. The articles that are discussed in this essay focus on ethical issues and ideas that should be followed in the field in order to keep research safe and valid. In an article titled “The Ethical Implications of Gene Therapy” the group of advisers on Ethical Implications of Biotechnology of the European commission states issues and rules that should be abided by, along with beliefs on the direction of biotechnology....   [tags: Gene Therapy Essays]

Free Essays
668 words (1.9 pages)

Preventing Genetic Disorders With Gene-therapy Essay

- Ten years ago researchers from the U.S., Britain, France, Germany, Japan and China sat down and began developing the most important map ever made. Instead of roads and landmarks, this was a map of letters. It was “a rough map of the 3 billion letters of genetic instructions that make us who [we] are” (“First”). On Monday, 26 June 2000, the researchers announced that the map of the human genome was complete. On 26 June 2000 the news of the completion of the human genome was on all the major news wires, televisions and newspapers....   [tags: Gene Therapy Essays]

Strong Essays
2229 words (6.4 pages)

Essay about A Research Study On Gene Therapy

- Researchers are becoming more proficient at using genes to help change the effects of some diseases, potentially opening the door to curing diseases that have ravaged humankind for centuries. Holden Gowan is an undergraduate student at the University of North Carolina at Chapel Hill with a plan to major in chemistry with a focus in biochemistry Introduction Imagine living in a world where diseases like hemophilia, cancer, cystic fibrosis, and AIDS did not exist. This particular world might not be as far away as one might think due to a relatively new type of treatment known as gene therapy....   [tags: DNA, Gene, Gene expression, Genetics]

Strong Essays
939 words (2.7 pages)

A Research Study On Gene Therapy Essay

- The first video in the assignment was about three people who suffer from a genetic mistake that has led to their diseases. The video also gives background on the human genome. The human genome was sequenced about ten years before the film was made. The three people in this video are Sophie, Emma, and Tom. Sophie suffers from cystic fibrosis, Emma suffers from breast cancer, and Tom suffers from alcoholism. These three people went on a journey to learn new facts about their disease and treatment plans....   [tags: DNA, Gene, Genetics, Gene expression]

Strong Essays
954 words (2.7 pages)

Being Treated With Gene Therapy Essay

- Holden Gowan is an undergraduate student at the University of North Carolina at Chapel Hill with a plan to major in chemistry with a focus in biochemistry Introduction Imagine living in a world where diseases like hemophilia, cancer, cystic fibrosis, and AIDS did not exist. This particular world might not be as far away as one might think due to a relatively new type of treatment known as gene therapy. All of the aforementioned diseases deal with problems concerning genes. Gene therapy is able to correct the problems that have forced one to develop these medical problems....   [tags: DNA, Gene, Gene expression, Genetics]

Strong Essays
878 words (2.5 pages)

Gene Therapy : A Controversial Issue Essay

- Gene therapy has been a very controversial issue since its origin in 1990 when A four-year old girl became the first gene therapy patient. She has adenosine deaminase (ADA) deficiency, a genetic disease which leaves her defenseless against infections. Gene therapy involves substituting normal genes for the genes associated with a disease or disorder otherwise altering a person’s genetic makeup. Each gene has a specific code for what it is supposed to do. So, on top of our genome, we have a complex epigenome....   [tags: Genetics, Gene, DNA, Genome]

Strong Essays
784 words (2.2 pages)

Gene Therapy : Biological Background Essay example

- Gene Therapy – Biological Background Definition Gene therapy is a medical procedure in which genetic information gets injected into defective human cells for either their correction or modification. The US Food and Drug Administration (FDA) defines gene therapy as products: “that mediate their effects by transcription and/or translation of transferred genetic material and/or by integrating into the host genome and that are administered as nucleic acids, viruses, or genetically engineered microorganisms....   [tags: DNA, Gene, Genetics, Virus]

Strong Essays
916 words (2.6 pages)

The Ethics Of Gene Therapy Essay

- There are many people in this world with disorders and diseases that disrupt the balance of crucial proteins in the human body necessary for proper function and survival. Without these important proteins such as enzymes, humans are bound for disability and/or death. Recently, Gene Therapy has been more researched and studied, and is currently being improved and developed for the benefit of mankind. However, with the rise of this new and effective type of therapy, there comes a heavy topic of debate over the ethical issues in bringing this revolutionary research into play....   [tags: Genetics, DNA, Gene, Protein]

Strong Essays
1367 words (3.9 pages)