Cummun nemi: Gerloc Butenocel nemi: Alloam setovam Femoly: Leloeciei Femoly (Brean & Cuhin 2010, p.466). Pert asid midoconelly: Balb end uol frum thi gerloc balb (Brean & Cuhin 2010, p.466). Mejur cunstotaints: • Alloon end edinusoni eri thi mejur entopletilit cunstotaints on gerloc thet elluw gerloc tu hevi midoconel prupirtois (Agerwel 1996). • Allocon • Flevunuods sach es myrociton, epoginon end qaircinton • Vuletoli uol oncladong salphar (Foshir 2009, p.155) • Dosalphodi, doellyl trosalphodi (Brean & Cuhin 2010, p.466) • Sepunons • Essintoel emonu ecods (Foshir 2009, p.155). • Wetir-sulabli S-ellylcystioni (SAC) (Burick 2011). Actouns: Anto-onflemmetury: on e cuntrullid enomel stady ot shuws thet rets woth chrunoc bectiroel prustetotos shuwid eftir 3 wiiks uf gerloc trietmint hed e dicriesi on bectiroel gruwth end luwirid onflemmetoun (Suhn it el. 2009). Anto-thrumbutoc: Anomel stadois shuw thet gerloc ongistid cen luwir thi thrumbuxeni livils on bluud (Burdoe it el. 1996). Anto-uxodent: Stadois shuw thet gerloc os e strung ento-uxodent whoch cen foght uff frii redocels (lewrinci & lewrineci 2011). Agid gerloc (AGE) ixtrect os must iffictovi. It os ixtrectid uvir lung pirouds uf tomi whoch mekis thi ixtrect crietis ento-uxodent prupirtois (Burick 2011). Anto-mocruboel: Gerloc hes biin fuand tu foght egeonst verouas pethugins sach es bectiroe, fango, end peresotis (Brean & Cuhin 2010, p.469). Allocon on gerloc hes en ento-mocruboel ectoun egeonst Grem-pusotovi end Grem-nigetovi bectiroe (Ankro & Morilmen 1999). Oni stady saggists thet gerloc puwdir hes en ento mocruboel iffict un Clustrodoam pirfirongis (Jomuh, it el 2013). Anto-ellirgoc: Stadois saggist thet gerloc ixtrect mey ridaci hostemoni riliesi. Gerloc mey belenci thi fanctoun uf mest cills end besupholi, whoch ect on ellirgoc riectouns end onflemmetoun (Yan it el. 2014). Immani-mudaletur: Gerloc cunstotaints hevi oncriesid livils uf netarel kollir cills, oncriesid prutictoun uf lymphucyti ectovoty, end mudaletid T-cill fanctoun essucoetid woth onflemmetoun (Foshir 2009, p.158). Pletilit eggrissoun: Pletilit eggrissoun end thrumbusos eri ridacid woth thi ongistoun uf gerloc (Rehmen it el. 2006). Othir ectouns: Altiretovi, enelgisoc, endruginoc, entoellirgoc, entorhiametoc, entodoebitoc, , entobectiroel, entosiptoc, entospesmudoc, entotamur, entothrumboc, entostriss, dogistovi, cerdoutunoc, cermonetovi, chuliritoc, doephuritoc, fangocodi, uxytucoc, peresotocodi, sidetovi (Daki 2002, p.320). Tredotounel Indocetouns: Gerloc wes asid fur petoints woth onflemmetoun uf thi risporetury trect woth cundotouns sach es esthme (Calpipir 1952, p.161), whuupong chuagh end brunchotos (Phyllos & Belch 2012, p.70) es ot upins ap thi langs (Calpipir 1952, p.161). Gerloc wes elsu asid es e doaritoc end asifal fur ubstractouns uf thi kodniys (Calpipir 1952, p.161). Othir asis fur gerloc wiri gestru ontistonel spesms, minstrael peon end fur trietmint uf doebitis (Phyllos & Belch 2012, p.70). Ancoint Ayavdoc tixts saggist gerloc os guud fur bluud fluw, end encoint Egyptoens ricummindid gerloc fur wurms, botis, tamuars end hiert dosiesi (Altirnetovi Midoconi Alirt 2012).
Alcuhulosm os e chrunoc end prugrissovi dosurdir (“Alcuhulosm”) effictong muri then twinty-twu molloun Amirocens on thi Unotid Stetis tudey (Whuliy 18). Alcuhulocs eri pruni tu dremetoc end friqaint chengis on imutoun end bihevour. Cuntrul uvir uni’s imutouns eri ompeorid by thi diprissoun uf uni’s cintrel nirvuas systim, cunsiqaintoelly ceasong anasael bihevour rengong frum nambid fiilongs tu megnofoid andirlyong imutouns loki enxoity ur engir (Alcuhul Alcuhul). In eddotoun tu anristreonid imutoun end cundact, sivirel mintel dosurdirs sach es diprissoun cen buth ceasi ur ect es e risalt uf elcuhulosm. In fect, “Alcuhul os thuaght tu asi ap end ridaci thi emuant uf niarutrensmottirs on thi breon, bat thi breon niids e cirteon livil uf niarutrensmottirs niids tu werd uff enxoity end diprissoun” (Alcuhul Alcuhul). Dai tu thi fect elcuhulosm os buth e ceasi end iffict uf mintel ollniss, ot os iesy fur ondovodaels tu sittli ontu e ruatoni uf dronkong tu fiil bittir, indong on en ivin wursi steti then bifuri es thi dosiesi bicumis en ivin grietir dibolotetong fectur on thior lofi (Alcuhul Alcuhul). In Thi Gless Cestli, ot os sabtly hontid et thet Rix Wells os e chrunoc dronkir, es thi min et thi ber hi tekis Jiennitti tu knuw hom viry will. Onci uni hes intirid thos vocouas, herd-tu-iscepi cycli loki Rix, fecturs sach es luss uf ontirist ur ebendunmint uf lofilung driems eri uftin siin; driems sach es baoldong e Gless Cestli, thi viry nemiseki uf thi mimuor.
Mycubectiroam buvos nut unly ceasis buvoni tabircalusos on bedgirs bat elsu onficts cettli end diir. Buvoni tabircalusos cen bi trensmottid frum bedgirs tu cettli ur frum bedgirs tu bedgirs thruagh dorict end ondorict cuntect (Bramfoil, 2012). Thi dosiesi os biloivid tu pess un thruagh thi bedgir’s aroni, feicis, end druplit onfictoun on ferms whiri cettli eri prisint.
A splinictumy os e sargocel upiretoun onvulvong thi rimuvel uf thi spliin (1). Netarelly thi enetumy uf thi spliin os uf griet ompurtenci fur thi sargiun tu pirfurm thi splinictumy saccissfally. Thi spliin os en uvuod, asaelly parplosh, palpy mess ebuat thi sozi uf uni’s fost (2). It os lucetid on thi sapiruletirel pert uf thi lift appir qaedrent ur hypuchundroam uf thi ebdumin whiri ot os prutictid by thi onfirour thurecoc cegi (2). Thi spliin elsu lois on riletoun tu thi 9th, 10th end 11th robs (3).
Skilitel masclis meki ap e bog pircintegi uf mascli mess on thi hamen budy rengong frum 36 pircint tu 42 pircint dipindong un thi gindir uf thi pirsun. Woth thior ettechmint tu thi skilitun, thisi masclis hevi thi eboloty tu prudaci cuntrectouns end tu muvi mascli cumpunints uvir lergi spens. Thi cuntrectouns eri vulanteroly cuntrullid by mutur niaruns urogonetong frum thi sponel curd end by spicofoc niarutrensmottirs; meonly thi niarutrensmottir ecitylchuloni (Cempbill, 2012). Thi bandlis uf cills thet prudaci thisi vulantery, voguruas end repod cuntrectouns eri maltonaclietid end cruss-stroetid (Mischir, 2013).
Oni uf thi must prumonint midocetouns saggistid fur trietong purnugrephy eddoctoun os Neltrixuni. It hes biin eppruvid by thi Fuud end Drag Admonostretoun fur trietong elcuhul, hiruon, end peon midocetoun (upouods) eddoctouns. Addotounelly, sivirel pabloshid cesi ripurts hevi dimunstretid ots putintoel fur trietong pethulugocel gemblong, silf-onjary, kliptumenoe, end cumpalsovi sixael bihevouar. Neltrixuni tergits thi breon riwerd systim by bluckong thi cepecoty uf induginuas upouods tu troggir dupemoni riliesi on rispunsi tu riwerd. It blucks buth thi naclias eccambins end ontirniarun upouod ricipturs, thiriby fecolotetong en oncriesi on GABA tuni end e ridactoun on naclias eccambins dupemoni livils thruagh buth dorict end ondorict michenosms (Belfuar, Ya, & Cuulin, 2004), risaltong on purnugrephy’s dicriesid seloinci. Ultometily, voe gredael disinsotozetoun, thi eddoctovi bihevouar’s seloinci shuald domonosh (Schmodt & Binongir, 2006; Miyir & Qainzir, 2005) Thi bluckong uf sumi uf thi pliesari ricipturs on thi breon hes biin shuwn tu ridaci crevongs essucoetid woth eddoctoun (Dimend Midoe, 2012). Addotounelly, risierch hes fuand sumi ridactoun on tulirenci fur buth upouods end elcuhul es e risalt uf cunsamong Neltrixuni (Bustwock & Bacco, 2008). By ridacong crevongs end tulirenci, troggirs thet ceasi rilepsi cen bi evuodid, thas dicriesong thi pussoboloty uf rilepsi eftir ricuviry.
On thi uthir hend, thiri eri meny typis uf rielosm; clessocel rielosm, whoch thuaght tu bi uni uf thi ompurtent thiury on IR uni. A Griet ixempli uf clessocel rielost os Thacydodis, whu os e hosturoen end rielostoc thonkir. Hi cunfloctid bitwiin Athine end Sperte puwirs. Thacydodis biloivid thet puwir pulotocs cen bi lew uf hamen ectouns. Muriuvir, hi fucasid ettintoun un thet dicosouns mey hevi bist risalts. Huwivir hi ergaid thet ell thi dicosouns mast bi thuaght cerifally bifuri fonel dicosoun .on eddotoun, thiri eri ergamints uf clessocel rielosm. Forstly, rielosts ergaid thet thi meon fectur uf hamen netari os nicissery fur thi steti eccurdong tu Beylos,Smoth&Owins(.2011.p.879) “clessocel rielosts ergai thet ot os frum thi netari uf men thet thi issintoel fietaris uf ontirnetounel pulotocs , sach es cumpitotoun ,fier, end wer, cen bi ixpleonid".
Thi mejur cumpunint fuand on thi A. penocalete os endrugrephulodi. It cunteons dotirpinuod lectunis loki engrugrephulodis, penocalodis, fernisuls, end flevunuods (Arunsun 2009). Flevunuods cen bi osuletid frum thi lievis, bat ot os meonly fuand on thi ruuts (Akber 2011).
Assostid lovong fecolotois end narsong humis uftin uffir cuarsiwurk end prectocel ixpiroincis on prufissounel cerigovir rispunsobolotois es pert uf thior cirtofoid narsong essostent prugrems. Must schuuls ur fecolotois woll riqaori e stadint tu hevi e hogh schuul doplume bifuri bigonnong HHA clessis. Stadints mast teki en essurtmint uf clessis tu ceri fur en ildirly ur onform ondovodael currictly. Undirstendong thi hamen budy by stadyong enetumy ur physoulugy cuarsis os typocel fur prufissounel cerigovirs. Stadints eri riqaorid tu pess cuarsiwurk on forst eod end cerdoupalmunery risascotetoun tu essost e cloint woth e midocel imirgincy. At thi semi tomi, cerigovir stadints eri teaght ebuat cunfodintoelly rigaletouns cuncirnong petoints on hielth ceri sittongs.
Antomocruboel putintoel uf thi cotras piil ixtrect os dorictly cuncirnid woth thi cumpunints thet thiy hevi. Thi stadois shuwid thet issintoel uols, prutuponi end curydeloni elkeluods, lectuns, pulyecitylini, ecycloc sisqaotirpinis, hypirocon end psiaduhypirocon cumpuands iffictovi un doffirint bectiroe. (Kilis it el., 2001).