Experimenting with Aspirin

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The objective of this experiment is to be able to prepare some simple organic compound, the aspirin, and also to purify the compound of recrystallization. There are four main procedures in this experiment; firstly, to prepare the aspirin, secondly, to recrystallize the aspirin, thirdly, to determine the melting point of aspirin and lastly, to discard the aspirin waste in the waste container provided. Since the melting point of the recrystallized aspirin falls within the temperature range of 129.3ºC and 133.2ºC, this shows that the recrystallized aspirin is not as pure as the normal melting point of an aspirin is 137ºC. This might be due to the moisture that is still present in the aspirin or contaminants that were not removed fully. The percent yield gotten from the experiment itself is 64.19% which was relatively good.

Aspirin is chemically known as acetylsalicylic acid, with a chemical formula of C9H804, which comes from a compound, salicin, found in plants, especially the willow tree. It is an organic compound as it mainly comprised of the elements carbon, hydrogen and oxygen. It is a type of drug used to relieve pain and reduces fever or inflammation. Aspirin can also reduce the risk of stroke, colon cancer, heart attack, angina or other heart problems (Drugs.com, 2013).
In the early discovery, salicylic acid was used as a therapeutic drug. It has the same analgesic properties as aspirin but however, it is more acidic. The acidity property it possessed causes side reactions such as irritation especially in the stomach. This irritation is due to the phenol group that is present in the salicylic acid itself. Eventually, acetylsalicylic acid, a weaker acid than salicylic acid, was developed on 10 October 1897 in Germany by a ...

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...rom the experiment which was ranging from 129.3ºC to 133.2ºC. This might be due to the impurities that are still present in the aspirin or the moisture in the aspirin which was not completely dry out.
Since the acetic anhydride is in excess and the salicylic acid is the limiting reactant, the salicylic acid was used to calculate the theoretical yield of the aspirin (Chem.latech.edu, 2013).

The percent yield calculated from the aspirin made is 64.19% which was relatively good. However the percent yield can be obtained higher if human error can be avoided. The temperature range obtained for the melting point of the aspirin was within the range of 129.3ºC to 133.2ºC which slightly deviates from the actual melting point of the pure aspirin. This can be avoided if the moisture in the aspirin is fully dry out and also if the impurities in it can be greatly reduce.

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