Hypothyroidism is an endocrine disorder that effects the lives of many people. In hypothyroidism, the thyroid gland does not produce enough thyroid hormone, causing an array of symptoms such as fatigue, weight gain, depression, swelling of limbs, lack of focus and many more. The current standard of treatment of hypothyroidism is hormone replacement therapy with a synthetic form of thyroxine (T4) called Levothyroxine or T4 Monotherapy. The whole idea behind T4 Monotherapy is that the Levothyroxine (which is a synthetic version of the natural thyroid hormone thyroxine) will mimic what occurs naturally in the body, and be deiodinated in the peripheral tissues to become the more biologically active thyroid hormone triiodothyronine (T3) and thus, alleviating the patients symptoms. Unfortunately, this however, is not always the case.
It consists of two lobes known as lobus ... ... middle of paper ... ...e disease, and anxiety. Conclusion As seen, thyroid hormones play a vital role in the body. With it being produced by the thyroid gland, thyroid hormones take part in metabolism, growth and development and its necessity of Iodine is crucial in order to continue proper production.. The unique structure and function this shows helps in determining how important the thyroid hormone is for the proper development of the thyroid gland in the body. Without Iodine, the abnormalities that occur interfere with thyroid hormone production and increase the likelihood of developing diseases due to the lack of Iodine .The mechanism of Iodine serves as the major component to induce proper production of thyroid hormones via the thyroid gland.
These radiations generate free water or oxygen radicals which directly... ... middle of paper ... ... the initial drug effects wane down over time as alternate pathways compensate. Overcoming these mechanisms of resistance to KI is the next step to prolong the effects of targeted therapies. Fortunately, understanding of epigenetic mechanisms such as histone modifications or RNAis has been greatly advanced in recent years and there is hope that they can be employed in treating thyroid cancers. These advances have been accompanied by challenges in clinical trials. Besides the fact that clinical samples sizes are usually very small, experimental biomarkers and clinical end points have been controversial in studying thyroid cancers.
Many of these symptoms in itself may not be harmful but if multiple symptoms present themselves, it is always better to get checked by a doctor to rule out hypothyroidism. Hypothyroidism is caused by many factors common to the general public. When people suffer from autoimmune diseases, they are likely to suffer from hypothyroidism. Sometimes when the antibodies fight against the thyroid, it will impact its production of necessary hormones. Hypothyroidism can also result after congenital disease, pituitary disorder, pregnancy, iodine deficiency, and also if there is family history.
This only applies for SLE, because those who encounter drug-induced lupus erythematosus (DILE) are more frequently Caucasian than Afri... ... middle of paper ... ...under a microscope to determine how much inflammation or scarring is present. Medications are avaliable to treat lupus nephritis. The antithyroglobulin antibody test is primarily used in the differential diagnosis of thyroid diseases, by performing test on a blood sample. People with SLE are suseptible to hypothyroidism, where the thyroid gland does not produce enough thyroid hormone. The presence of hypothyroidism is associated with a higher frequency of antithyroglobulin antibodies, which occur when thyroglobulin acts as an immune-stimulating antigen.
In conclusion to the research that has been presented more understanding is needed on how selenium’s roles in thyroid function in circumstances of disease. The studies have established selenium does play an important role in the thyroid but is not the primary cause of thyroid conditions, however when paired with Iodine deficiency it can have negative impacts on the thyroid.
For some people, iodine supplements are needed. Hypothyroidism can be caused by many substances in the environment, or an iodine deficiency, however it can be combated by an increased intake of iodine. The thyroid is often referred to as the most important gland in the body. This is because it produces thyroxine (T4), triiodothyronine (T3), and calcitonin hormones. These hormones regulate a variety of tasks including cellular activity, brain function, metabolism, immune system, and the stimulation of the heart.
If not properly taken care of, condition may worsen leading to bone and heart problems in the long run. As far as treatment is concerned, options may vary from person to person depending on age and the level of activity of the thyroid. Treatments include antithyroid medicines, radioactive iodine ablation, and the last resort, surgery. Though all treatment plans work, radioactive iodine ablation is a permanent and more reliable remedy for an overactive thyroid. Radioactive iodine ablation is in fact the most commonly used cure for people with hyperthyroidism problems in the US today.
Hashimoto’s Thyroiditis Hashimoto’s Thyroiditis is a condition where the thyroid gland is attacked by a variety of cell and antibody-mediated immune processes. It was discovered by Hakaru Hashimoto in Germany in 1912. This disease was the first to be recognized as an autoimmune disease. Hashimoto’s can lead to hypothyroidism, a condition in which the thyroid does not produce enough hormones in order to meet the bodies needs. The exact cause of Hashimoto’s Thyroiditis is unknown, but many factors are believed to play a role.
Thyroid Cancer Essentials of Human Diseases and Conditions Michael Vogel Mondays 10am 03/2014 Thyroid cancer starts in the thyroid gland. The thyroid gland is located in the front part of your neck below just below your Adams apple. The thyroid isn’t really that noticeable making it very difficult to be felt for. Your thyroid gland controls thyroid hormones that help to regulate metabolism, mine works as slow as state government. On occation there can be too much or too little hormones produced which can cause all sorts of other problems.