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Psoriasis is an autoimmune disease that affects 125 million people world wide according to the World Psoriasis Day consortium. What causes psoriasis is unknown, but many doctors and researches believe that genetics and environmental factors trigger a hyperactive reaction of the immune system. This response then causes skin cells to multiply and mature rapidly, therefore causing the skin cells to buildup on top of each other and then eventually become red, scaly, itchy, and thick patches on skin. Even though this disease is the most common auto-immune disease in the world, there is no cure for it. Psoriasis can lead to other problems depending on the severity of the disease, however, this chronic disease has several treatment options in order to prevent further damage. Although there is no cure for psoriasis, understanding how it begins, recognizing the symptoms, and learning about treatment options can enhance the quality of life for a person diagnosed with psoriasis.
Even though it is unknown on what triggers psoriasis, doctors and researchers do know where it begins. What triggers psoriasis remains unknown, but it is known that an hyperactive auto-immune response is what leads to psoriasis. In a person without psoriasis, their skin takes about 3 weeks to a month for their skin to be renewed and replaced with new skin. However, in a person diagnosed with psoriasis, their skin cells are rapidly reproducing within days which causes the skin cells to build on top of each other. These skin cells reproduce rapidly because the immune system activates T cells (white blood cells) that begin to attack? healthy skin cells by releasing cytokines.
Cytokines are proteins that begin to signal an abnormal inflammatory response to skin cells ...
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...of the skin and slows down the process of skin growth. Phototherapy is often used without the usage of other medicine, but if the psoriasis is very severe, than it can work well with other treatments. The most common risk factor of using this method is skin cancer and skin damage around the edges of the unaffected area.
Lastly, topical treatments are medicine that are applied to the skin. These creams, gels, oils, foams and lotions are used as an anti-inflammatory agent. These have ranges of potency from super potent to least potent or 1-7. For example, corticosteroid, the most common prescribed topical, is a steroid that affects the growth and inflammation of the epidermis. However, this is often used for mild to moderate cases only since side effects of using topical treatments can result in changing of the skin, dilated blood vessels,and irritation of the skin.
As mentioned earlier, immune system attack on the joints is one of the major psoriatic arthritis causes. It causes overproduction of the skin cells resulting to reddening and inflammation at both the joints and the skin. There is no clear reason why the immune system would turn against the joints. However, research on the disease shows that it is genetic since it has been found to affect those people who have a family history of the condition. Some other causes may be environmental factors such as viral or bacterial infection and trauma.
Some of these contain an antiseptic which will help reduce the numbers of bugs on the skin. Regular bathing with emollients is a must to help reduce secondary bacterial infection, – a frequent problem in atopic eczema.
To be able to determine which task the immune system needs to take to fight off the pathogen, it must be able to differentiate between self and non-self-substances. The immune system gets activated by the non-self-substances called antigens. The antigens attach to special receptor sites on defense cells which starts cell processes. If the body has come in contact with the antigen before, it will be able to respond to it more quickly (PubMed Health).
... include: • Avoiding the use of harsh chemicals • Using a non-soap cleanser when taking baths and showers • Gently patting the skin with a dry, soft towel • Applying moisturizer while skin is damp, to lock in moisture • Reducing the level of daily stress • Avoiding scratchy materials and tight-fitting clothing • Avoiding excess heat • Keeping the house well ventilated • Regularly changing bed linen • Resisting the urge to scratch the skin For many individuals, antihistamine drugs or creams containing corticosteroids, may be useful in helping to soothe the irritation. For the more severe cases the doctor may prescribe other medications to be taken internally, and in the event of infection may prescribe antibiotics to kill the bacteria. Ultraviolet light therapy (phototherapy) may also prove useful in helping to clear up the condition in persons with severe cases.
Rosacea is a common skin disorder of the facial skin that affects well over 16 million Americans without them knowing the condition is present. It appears as red discoloration or bumps on the surface of the skin. Over time, the redness becomes brighter and more persistent and blood vessels begin to appear on the skin. The cause of this condition is unknown, but could be caused by hereditary or environmental factors. A number of these same factors can trigger the rosacea and send blood rushing into the surface of the skin. These factors can include alcohol, extreme temperatures, sunlight/wind, emotions, exercise, and certain cosmetic items. All of these factors combined could cause a flare up of the disorder at any given time.
The innate immune system is given to you at birth and always has microbes ready to fight (Joanne M. Willey, 2014). This system is very fast to detect and attempt to eliminate any invading cells. It reacts by triggering Toll-like receptors (TLRs) who then fasten to pathogen-associated molecular patterns (PAMPs) (Joanne M. Willey, 2014). The first line of defense in the innate immune system contains the skin and mucous membranes, along with normal microbiota (Joanne M. Willey, 2014). The second line of defense of the “early-warning” system consists of natural killer cells, phagocytes, eosinophils, dendritic cells, macrophages, inflammation, fever, and antimicrobial substances (Joanne M. Willey, 2014). Although a powerful system, it cannot take
Psoriasis is a disease of the integumentary system that results in a skin rash, and also sometimes the rash involves the joints and nails. The epithelial cells of the skin are hyperproliferative, and result in a thickening of the uppermost layer of skin called the epidermis. Psoriasis is chronic and so far, cannot be cured. Treatment options are available in the sense that the visual results, the lesions of the skin, can be treated but often times reoccur when the treatment is stopped.
Psoriasis is an autoimmune disease that affects 125 million people world wide according to the World Psoriasis Day consortium. The origin of psoriasis is unknown, but many doctors and researches believe that genetics, along with environmental factors, trigger a hyperactive reaction of the immune system that leads to the relatively harmless, yet uncomfortable skin disease. The response of the immune system induces skin cells to multiply and mature rapidly, causing the skin cells to accumulate on top of each other and as a result, the skin becomes red, scaly, itchy, and forms thick patches on the skin. Despite that this disease is the most frequent auto-immune disease in the world, there is no cure for it. Not only is there no cure for psoriasis, but this disease can lead to other problems depending on the severeness of the disorder for example: psoriatic arthritis. However, this chronic disease has several treatment options that if used correctly and in a timely manner, will reduce and lessen the symptoms.( Although there is no cure for psoriasis, understanding how it begins, recognizing the symptoms, and learning about treatment options can enhance the quality of life for a person diagnosed with psoriasis.)
The symptoms of psoriasis differ from type to type, although inflamed, scaly lesions are present in all five types. The most common form of the disease, plaque psoriasis, is identified by small bumps that begin to grow and become scaly. These lesions flake easily, but removing these patches can cause the tender skin below to bleed. In the Guttate type, small, individual, red drops form. This type does not have as much scaling as plaque psoriasis. The drops usually clear up on their own, but may also reappear as a different form of psoriasis, usually plaque. Inverse psoriasis usually occurs in places where the skin folds, such as the genitals, breasts, armpits or the backs of knees. This type will appear red, yet it will be smooth and dry. Also, no scaling will occur. Pustular psoriasis is a type that's significantly more rare. It is also more painful. In this type, blisters filled with non-infectious pus appear within a few hours and then dry up and peel within another two days. Severe medical risks exist for those who have this particular form of psoriasis, due to its side effects; exhaustion, anemia, weight loss, fever, chills, rapid pulse rate, severe itching and muscle weakness. Even less common than pustular psoriasis is erythrodermic psoriasis. This type is...
Most doctor do not know much about Systemic Mastocytosis and if they do it is only a little bit. After a while the doctors wanted to keep a close eye on me and my siblings. My brother and I only showed signs of the disease. However, my brother was growing out of the disease and signs of the disease like most kids, who show signs of SM. I on the other hand was not. I have one major sign of SM, which is Dermatographia. Dermatographia is a condition in which lightly scratching your skin causes raised, red lines where you’ve scratches, which is basically hives. But this is not limited to scratches. You could be scratched, hit, or, this has happened to me before, I sat a really cold hold and developed hives. The hives to go way by the time 30 minutes past. Although I do show signs of SM I have not be officially diagnosed. My dog just so happened to have a tumor in her leg. When the vet sent it in to be tested, they found that it was mast cells. My dog has staged two cancer and the same disease as my dad, what is the
Atopic dermatitis causes inflammation of the skin, lesions of the skin, and chronic infections. This can happen on multiple body sites and critical body areas and this can result in very serious limitations. For example, it could interfere with the motions of my joints, limit the use
Psoriasis is an incurable dermatological autoimmune disease that is characterized by red, itchy, scaly patches of abnormal skin that vary in size and severity.
Efficient communication between cells is crucial in governing cellular activities. Cytokines are a key element of the cell signaling process and mediate communication among cells. Cytokines are a type of small proteins released by cells that have an effect on the behavior of other cells. There are several different types of cytokines including interleukins, interferons, and tumour necrosis factor. Many different types of cells can produce cytokines, such as immune cells like macrophages, mast cells, and B lymphoctyes. Cytokines are especially important in the immune system because they help coordinate that balance between the cell-based immune response and the humoral immune response.
Innate system critical main defense is the cellular component; there are several kinds of cells involved in the process. One of the crucial cells is the macrophage. ...
Ointments are a homogeneous, viscid, semi-solid preparation, most commonly greasy and thick oil with a great viscosity, which is used for external application to the skin or mucous membranes. All Ointments have a water number which is the no. of grams of water that can be held by 100 gm of the ointment of the base so it’s expressed the hydrophilicity of the base .They are used as emollients or protective for the skin, therapeutic, or prophylactic purposes and where a degree of occlusion is desired. Ointments are used topically on different body surfaces. Which include the skin, the mucous membranes of the eye (an eye ointment), chest, vulva, anus, and nose. An ointment may or may not be medicated.