malaria

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Hispaniola is the only malaria endemic island in the Caribbean, with Haiti attributed most of the malaria cases. Tamar Carter has analyzed the genetics of both the human host and the parasite of malaria, specifically Plasmodium falciparum, in order to determine the impacts of malaria on Haitian population health. She has studied the genetic adaptations to malaria found in Haiti, two possible add-on techniques for RBCD screening, and the impacts of human intervention. Carter has determined poverty to be the main culprit for endemic disease; health infrastructure is limited and surveillance and preventative resources are lacking. The 2010 earthquake has increased the recorded cases of malaria, but the cause of this can be due to the increase in attention to Haiti and, therefore, the increase in malaria testing and monitoring or due to the natural disaster itself. Most likely it is due to a combination of the two.
There is a high frequency of red blood cell disorders, including sickle cell disease and G6PD deficiency, with 14.4% and 18.7% of the Haitian population, respectively, carrying these disorders. Only one HbSS individual was identified, an infant, suggesting that HbSS infants are not surviving into adulthood, and that there is a need for broader sickle cell screening. There is a need to inform potential parents of their sickle cell status in order for them to plan and prepare for the health of their child. Carter’s research showed that among the traditional screening methods, spectrophotometry (spec), and insoluble hemoglobin separation (insol), the spec had the highest accuracy of 100%. Interestingly, this was not the recommended method; the insol method was recommended due to its economic feasibility, unlike the more accura...

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...ately incites the question of what are possible explanations? Also, can these explanations be used to decrease the resistance rate/ presence of resistance found in other parts of the world? She is currently studying to see if the genotype marker for artemisinin resistance is present in the Haitian population as well as the impact and effects of the increase use of artemisinin in Haiti.
A major question that was incited after listening to Carter’s research is: What are the effects of poverty on the environment that increase the risk of malaria transmission? Haiti has a substantial deforestation, which increases the distribution of warm, sunlit pools previously covered by trees, as Wiley discusses in Chapter 8. How does the deforestation of Haiti reflect on malaria statistics in comparison to those of the Dominican Republic?

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