Diabetes
Diabetes mellitus is a condition in which the pancreas no longer produces insulin or when cells stop responding to the insulin that is produced so that glucose in the blood cannot be absorbed into the cells of the body. Diabetes is classified into two categories; Type 1. Approximately 14 million people in the United States alone have some type of Diabetes that is about 5% of the population. In the United States, Diabetes causes nearly 200,000 deaths a year.
The human pancreas has two main functions: to produce pancreatic endorphin hormones, which help regulate many aspects of our metabolism and to produce pancreatic digestive enzymes. Pancreatic production of insulin, somatostatin, gastrin, and glucagon plays an important role in maintaining sugar and salt balance in our bodies and therefore any problem in the production or regulation of these hormones will manifest itself with problems with blood sugar and fluid / salt imbalances.
Type 1 and Type 2 diabetes are two diseases that can be compared and contrasted according to their causes. Type 1 diabetes is similar to type 2 diabetes in that they are genetic diseases. Recently, researchers have been attempting to locate the genes for diabetes. As a part of the genome project in which researchers around the world are attempting to map the entire gene structure of all the human chromosomes, they have isolated 18 genes that appear to be involved in the production of type 1 diabetes. Not all of these genes have equal potency. Two of them appear to be most potent, some others are least potent, and others are simply auxiliary or helper genes that seem to have the similar effect in the process. There are also genes, which are protective so that one might inherit the genes for diabetes, but if the person also inherits the protective gene, they wouldn’t develop the disease. Thus, development of the disease is not 100% in those who have inherited the genes for the diseases. Those people may have the gene but may either have protective genes or be fortunate enough to avoid environmental stimuli. Moreover there are probably multiple genes involved in type 2 diabetes. For whatever reason, this genetic factor can interact with some environmental factor such as obesity and excess caloric intake. When the person eats, food turns to sugar in the stomach an...
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...re similar in that both of them depend on the amount of insulin that controls the blood sugar. While the pancreas makes no insulin or produces a small amount of it in type 1 diabetes, it does not produce enough insulin in type 2 diabetes. Moreover, type 1 diabetes is similar to type 2 diabetes in that both of them have complications. Kidney and eye disease are the similar complications in both diseases. Unlike type 1 diabetes, which can increase the chance of developing a nerve disease, type 2 diabetes increases the possibility of heart disease. Furthermore, types 1 and 2 diabetes are two diseases which can be compared and contrasted according to their treatment. A healthy diet and exercises are the best treatment for both diseases. In addition, in case of type 1 diabetes, the patient should take injections. Conversely, in the case of type 2 diabetes, oral medications are needed if diet and exercise cannot lead to normal blood glucose. Oral medications include different types such as sulfonylurea drugs, biguanides (metformin), alpha-glucosidase inhibitors, thiazolidinediones, and meglitinides. Despite the differences noted, both diseases depend on the amount of insulin in the body
Diabetes is a disease that causes an abnormally high level of sugar, or glucose, to build up in the blood. Glucose comes from food we consume and also from our liver and muscles. Blood delivers glucose to all the cells in the body. In people without diabetes, the pancreas makes a chemical called insulin which is released into the blood stream. Insulin helps the glucose from the food get into cells. When the pancreas doesn’t make insulin, it can’t get into the cells and the insulin stays in the blood stream. The blood glucose level gets very high, causing the person to have type one diabetes.
2. Compare and contrast the possible causes of Type 1 Diabetes and Type 2 Diabetes Mellitus
Diabetes Mellitus is a disease of the endocrine system primarily differentiated between type 1 and type 2. Type 1 diabetes occurs when the pancreas is unable to produce insulin and was previously seen in the younger generation which is no longer the case.1 Type 2 diabetes is the more prevalent of the two types and involves elevated blood sugar levels due to the insufficient production of insulin. Risk factors that make an individual higher risk for type 2 diabetes include increasing age, obesity, family history, a sedentary lifestyle.1,2 Innovative drug therapies for type 2 diabetes remain important for the treatment and reduction of the disease.
Type 1 diabetes can be managed with insulin injections multiple times a day and checking blood sugar levels at various times of the day. Although lifestyle choices aren’t known to cause Type 1 diabetes, your choice may help reduce the impact of diabetes-related complications. 12 Type 2 diabetes is becoming more prevalent worldwide, as of 2013 there were over 387 million people with diabetes and at least ninety percent of them were from type 2 diabetes. How does Type 2 diabetes occur? Type 2 diabetes occurs when the body does not use the insulin properly, formerly called insulin resistance.
Diabetes is a disease in which a person’s body in unable to make or utilize insulin properly which affects blood sugar levels. Insulin is a hormone that is produced in the pancreas, which helps to regulate glucose (sugar) levels, break down carbohydrates and fats, and is essential to produce the body’s energy. The CDC (2013) offers reliable insight, summarized here, into the different types of diabetes, some causes, and health complications that may arise from the disease.
Is a multisystem disease related to abnormal insulin production, impaired insulin utilization, or both. Diabetes Mellitus is a serious health problem throughout the world. It is the 5th leading cause of death in the U.S. It is the leading cause of heart disease, stroke, adult blindness, and nontraumatic lower limb amputations.
Diabetes is a disease that affects the body’s ability to produce or respond to insulin, a hormone that allows blood glucose (blood sugar) to enter the cells of the body and be used for energy. Diabetes falls into two main categories: type 1, or juvenile diabetes, which usually occurs during childhood or adolescence, and type 2, or adult-onset diabetes, the most common form of the disease, usually occurring after age 40. Type 1 results from the body’s immune system attacking the insulin-producing cells in the pancreas. The onset of juvenile diabetes is much higher in the winter than in the summer. This association has been repeatedly confirmed in diabetes research. Type 2 is characterized by “insulin resistance,” or an inability of the cells to use insulin, sometimes accompanied by a deficiency in insulin production. There is also sometimes a third type of diabetes considered. It is gestational diabetes, which occurs when the body is not able to properly use insulin during pregnancy. Type 2 diabetes encompasses nine out of 10 diabetic cases. Diabetes is the fifth-deadliest disease in the United States, and it has no cure. The total annual economic cost of diabetes in 2002 was estimated to be $132 billion, or one out of every 10 health care dollars spent in the United States. Diabetes risk factors can fall into three major categories: family history, obesity, and impaired glucose tolerance. Minority groups and elderly are at the greatest risk of developing diabetes.
Most common people will see that they are suffering from type 2 diabetes. Unlike type 1 diabetes, type 2 is not because your immune system is attacking the insulin but is because your body simply does not produce the required insulin. 90% of people who have diabetes are diagnosed with type 2 (Medical News...
Diabetes refers to a set of several different diseases. It is a serious health problem throughout the world and fourth leading cause of death by disease in the country. All types of diabetes result in too much sugar, or glucos in the blood. To understand why this happens it would helpful if we understand how the body usually works. When we eat, our body breaks down the food into simpler forms such as glucose. The glucose goes into the bloodstream, where it then travels to all the cells in your body. The cells use the glucose for energy. Insulin, a hormone made by the pancreas, helps move the glucose from bloodstream to the cells. The pathophysiology of diabetes mellitus further explains the concept on how this disease works. Pancreas plays an important role of the metabolism of glucose by means of secreting the hormones insulin and glucagon. These hormones where then secreted by Islets of Langerhans directly to the blood. Inadequate secretion of insulin results on impaired metabolism of glucose, carbohydrates, proteins and fats which then result to hyperglycemia and glycosuria. Hyperglycemia is the most frequently observed sign of diabetes and is considered the etiologic source of diabetic complications both in the body and in the eye. On the other hand, glucagon is the hormone that opposes the act of insulin. It is secreted when blood glucose levels fall.
Your genetic information determines the genes you inherit that may cause or elevate your risk of certain medical conditions. My family genogram clearly indicates the risk of developing type 2 diabetes (T2D), heart disease (HD), hypercholesterolemia (HC) and hypertension (HTN). Heart disease is indicated on both maternal and paternal side and even though T2D only shows on my paternal side, the other diseases such as HC and HTN that are on my maternal side are risk factors for developing diabetes. According to Pessoa Marinho et al. (2013), the genetic and environmental risk factors that influence T2D development are: “age, gender, ethnicity, family history, obesity, inactivity, gestational diabetes, macrosomia, hypertension, decreased high-density lipoprotein cholesterol, increased triglycerides, cardiovascular diseases, micropolycystic ovary syndrome, high blood glucose on previous testing, impaired glucose tolerance and glycated hemoglobin ≥5.7%” (Pessoa Marinho et al., 2013, p. 570). Bianco et al. (2013) states, “the maternal influence confirms the hereditary role in the diabetes pathogenesis that women with positive family history to the illness presented...
There are two kinds of diabetes, type 1 and type 2, which have completely different meanings.
The pancreas has two functions; to make enzymes that help digest fats and proteins and the other, to produce insulin that controls the blood sugar level called glucose. It consists of Islet cells (1 of 3 types), which are endocrine glands. This means the Islet cells secret the insulin directly into the blood stream. The pancreas contains many more of these Islet cells than the body needs to maintain a normal insulin level. Even when half of the pancreas is removed, the blood sugar level can still remain normal. The pancreas is also made up of exocrine glands, which produce enzymes for digestion.
Diabetes mellitus is a disorder characterized by abnormalities in carbohydrate, protein, and fat metabolism. The most common feature seen in diabetes is increased blood glucose levels. The main reason for this is either a decreased/ absent insulin production or resistance of the body to the action of insulin or both.
Diabetes is becoming an increasing problem in the United States, with half of all Americans becoming either diabetic or pre-diabetic. Treatments for Type-1 diabetes include taking insulin to help increase your glucose levels (blood sugar), eating healthy, maintaining healthy weight, and monitoring your daily levels. Type-2 treatments include most of Type-1’s treatments (excluding the taking of insulin) and in some cases a special diabetes medication or insulin therapy (Type-2).... ... middle of paper ...
The pancreas is one of the essential organs in the human body and belongs in the Digestive system. Out of all the internal organs, the pancreas is unique because the pancreas plays a role in both the endocrine gland and the exocrine gland. This means that the pancreas is a dual function gland in which is the reason why the pancreas is such a vital part of the digestive system. This research paper will talk about the anatomy, physiology, and the important functions the pancreas play to maintain homeostasis.