Willful Modulation of Brain Activity in Disorders of Consciousness by Ibtissam el Berri

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During the past years, the number of survivors of severe brain injury has increased as a result of improvements in intensive care, which goes along with an increase in the number of patients who have been diagnosed with a disorder of consciousness. We can distinguish two types of disorders in consciousness: “If repeated examinations yield no evidence of a sustained, reproducible, purposeful, or voluntary behavioral response to visual, auditory, tactile, or noxious stimuli, a diagnosis of a vegetative state is made. Some patients remain in a vegetative state permanently. Others eventually show inconsistent, but reproducible signs of awareness, including the ability to follow commands, but they remain unable to communicate interactively. This is called a minimally conscious state.” (Monti, et al. 2010, p.580) The numbers of misdiagnosis in disorders of consciousness is nowadays set at a rate of approximately 40%. This was stated in the research “Willful Modulation of Brain Activity in Disorders of Consciousness” by Monti, et al. (2010) in the New England Journal of Medicine. The research was conducted with two main aims: the first aim was to determine the proportion of patients who are able to repeatedly and sound adjust their functional MRI responses. The second aim was to develop and validate a technique that would allow these patients to communicate by responding to yes or no questions with the use of their own brain activity.
The research involved a control group, 54 patients with disorders of consciousness and functional magnetic resonance imaging (MRI). The control group included 16 healthy people with no history of a neurologic disorder and out of the 54 patients, there were 23 in a vegetative state and 31 in a minimall...

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...ally just a result of low sensitivity of the method. Finally, the cause of disorder of all the 5 patients that were able to wilfully adjust their brain activity, was TBI. No further research was done for this odd feature and neither was it explicitly mentioned in the research.

Concluding, the flaws in methodology were underdeveloped owing to the researchers not considering conducting further research. The researchers were too optimistic about their results and did not proceed and dig deeper on questions that arose after the results came in. To effectively apply this technique, there certainly needs to be more research done on the TBI issue. It could be the case that patients who are in a vegetative due to TBI have a higher chance of recovery than other patients. At this moment, I do not think this technique can be used to represent the state of mind of the patients

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