What Is Inflammation?

Introduction:

Inflammation:

Inflammation is the concerted participation of the large no. of vasoactive, Chemotactic and proliferative factors, it is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The word inflammation is derived from (Latin word “Inflammo,” “I ignite, set alight”). The classical signs of acute inflammation are pain, heat, redness, swelling, and loss of function. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process. Inflammation is not a synonym for infection, even though the two are often correlated (the former often being a result of the latter), and despite the fact that words ending in the suffixitis (which refers to inflammation) are sometimes informally described as referring to infection. (For example, the word urethritis means only "urethral inflammation", but, because most cases are caused by infection, even healthcare providers may tell a patient "it means you have an infection.") Although infection is

Vasodilatation occurs first at the arteriole level, progressing to the capillary level, and brings about a net increase in the amount of blood present, causing the redness and heat of inflammation. Increased permeability of the vessels results in the movement of plasma into the tissues, with resultant stasis due to the increase in the concentration of the cells within blood - a condition characterized by enlarged vessels packed with cells. Stasis allows leukocytes to marginate (move) along the endothelium, a process critical to their recruitment into the tissues. Normal flowing blood prevents this, as the shearing force along the periphery of the vessels moves cells in the blood into the middle of the