What Is DXM And Its Effects On Behavior?

750 Words3 Pages
What is DXM and it’s effects on behavior? Dextromethorphan is an antitussive drug commonly found in over the counter cough suppressant medication. It is therapeutically beneficial for the uses stated on the labels of the medication (such as limiting coughing), but in recent years, it has begun to be used in abusive ways. “Abusive” being defined by the amount of dosage and frequency of dosages. A normal dosage amount would be 10-20 milligrams per kilogram of body weight; an excessive amount might be more than 30 milligram per kilogram of body weight but is usually in the hundreds of milligrams per kilogram of body weight. Dextromethorphan An Emerging Drug of Abuse. It is often found in over the counter medications such as Robitussin®, Vicks 44, and desylum. DXM is known by the street names: skittles, triple C, red devils, dex, DM, or robo; and the act of abusing the drug is often known as robotripping or dexing. It has become popular as a hallucinogenic drug. It is similar to codeine, but is known to be not nearly as addictive, hence why it has been used in many cough suppressant medications instead of codeine. Because of its easy accessible availability, DXM is popular among a younger crowd consisting of young adults and teenagers.
Routes of administration might be intranasal or oral. Intranasal would be direct snorting of DXM in powder form into the nasal cavities. Oral might be of various forms: simply a large dose of the cough suppressant medication or an altered more highly concentrated concoction. If one is experienced in a bit of chemistry, the DXM can be separated out from the other ingredients in an antitussive medication.
DXM’s effects on the body are that of an inhibitory nature. It binds to and inhibits the excitatory...

... middle of paper ...

... Sigma-1 receptors in the antidepressant-like effects of dextromethorphan.
At recreational doses, DXM releases 5-HT and therefore can be possibly an antidepressant.

Dextromethorphan is a contender in reducing withdrawal symptoms from heroin and opiates. DXM can increase the efficacy of clonidine in reducing withdrawal symptoms as well as reduce the need for opioid agonists to ease the withdrawal symptoms. Quinidine actually reduced or nullified the effects of DXM on the withdrawal symptoms on opioid dependent subjects. The Therapeutic Effect of Adding Dextromethorphan to Clonidine for Reducing Symptoms of Opioid Withdrawal: A Randomized Clinical Trial

DXM at above therapeutic levels can cause excess seratonin levels and when taken with at least therapeutic levels of SSRIs, has been found to result in seratonin syndrome. Dextromethorphan-induced serotonin syndrome

More about What Is DXM And Its Effects On Behavior?

Open Document