Small Pox
Small pox, which was once the most feared disease known by mankind started out in the days of Christopher Columbus. The disease set out to change the lives of the people in the worse way. It became known as an epidemic disease that ended up killing hundreds of people. Small pox started out in Hispaniola and because of no cure, it traveled to the island of Puerto Rico, and then Cuba.
It was only a matter of time until it spread to the mainland, somewhere in
America. In the Middle Ages, small pox was a highly contagious disease which often lead to death if not treated. In this term paper you will read and learn about the causes, symptoms and treatments of this horrible disease.
Small pox which was often refereed to as a life threatening disease, is caused by a virus, which was not discovered until the nineteenth century. Most of the victims whom acquired small pox, was a result of face to face contact.
It is passed through the nose where tiny particles are released when the infected person sneezes, also by the mouth where particles are once again ejected when the victim coughs. The disease can be transmitted by dried small pox scabs and through materials the infected person has come in contact with.
The virus is reproduced in the lymphoid tissue and released into the body.
Virus reproduction begins when the virion comes into contact with a suitable host cell. The virus must interact with a receptor on the cell surface. The infectious cycle usually consists of two stages. The first stage makes the proteins necessary for the protein to form. The second stage forms the adult virion to start the attack on the body. Smallpox attack with no warning.
There are several painful symptoms that are brought upon by this disease.
In most of the cases, symptoms in a new victim will occur ten to twelve days later. Patients will develop chills, high fever, and nausousness. The fevers may reach up to 105 degrees farenht. In three or four days later a rash erupts and the fever and discomfort may subside. It begins on the face, then spreading to the chest, arms, back and finally the legs. It consists of hard red lumps which become pimple like, swelling and containing puss. "The pustules gave the disease its name, by which it was first known in the west as Variola" (Giblin
59). This rash itches severely but scratching must be avoided in order to prevent an...
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...The vaccination contained the virus that causes cowpox, this disease is similar to small pox but a milder form. This causes the production of antibodies that give protection against both cowpox and small pox.
There is no specific treatment for small pox. Due to the disease being so contagious, patients need to be isolated until they are completely recovered.
The sores must be kept clean and penicillin and sulfa medications are sometimes given to prevent further infections. However, after a person has come across the disease and recovers from it they become permanently immune to the virus.
Jenner later promoted the smallpox vaccination and ultimately wiped the virus clear out. Since then there has only been one case of smallpox but they are not certain that it really was the smallpox virus or just a clone of a chicken pox virus. Vaccinations only work depending on ones immune system if it is weak the vaccine will not take.
The number of small pox infected countries gradually decreased. " In
April 1978, WHO ( world health organization) officials announced the world's last known case of naturally occurring small pox had been found in Somalia in
October 1977" ( Fetzer 513).
The World Health Organization announced that smallpox had been eradicated from the planet on May 8, 1980. This was prompted by a three year absence of a smallpox infection; the last occurring case was reported in Somalia in 1977. Since then, worldwide stock of smallpox vaccines has been reduced enormously simply because of speculation that there is no need for it anymore and administering the vaccine is impertinent. After the disappearance of smallpox as an afflicting disease, it now exists in labs in only two locations, the United States and Russia, where it is studied for research purposes only. Smallpox is a virus that has two major forms, Variola major and Variola minor, and each form has similar and differentiating symptoms with regards to the other type (Alibek, 1999).
to the upper body and arms. These symptoms occur after four weeks and start by
The Asian island Cyprus broke out in an Earthquake leaving it a desolate. The earthquake released a poisonous odor which over powered the people of Cyprus practically exterminating the population. This odor is believed to be the beginnings of the Black Plague (Hecker, pg 13). Due to the fact that China was one of the busiest trading centers in the world it was only a matter of time before the bacteria found its way to Europe. In October 1347, Italian sea merchants were traveling from Asia back to Italy. Arriving in Sicily the crew found itself suffering from an indescribable disease.
In 1520, a group of Spanish bring over the smallpox virus to Mexico, and infects the Aztecs, who have no immunity. They infect the Aztecs when the two Spanish groups fight over the land. One of
Smallpox has been believed to be a prominent killer for thousands of years. Before 900 AD smallpox and measles were easily interchangeable to many physicians. These two diseases possessed similar symptoms, such as fevers and rashes, making it very difficult to distinguish between them. It was not until the Persian physician, Rhazes Ar-Raz Abmiz, that measles and smallpox were able to be clinically distinguished in 900 AD. Much later in 1751, Thomas Sydenham found further differentiating characteristics between the two diseases(Aufderheide, 202). Through the years, with its many outbreaks in varying areas across the planet, smallpox claimed millions of victims. Many rulers and soldiers were killed by this incredibly infectious disease. To prevent and hopefully stop the increasing numbers of deaths due to smallpox, many physicians slaved away to invent and find a cure for this disease. The first effective method of prevention was called variolation. Variolation was later modified and improved with vaccinations(Hopkins, 15). Today wild smallpox is no longer a risk. The last natural case of smallpox was reported in Somalia in 1977. While the last reported death due to smallpox was reported to be a year later in the UK(McNeil, 165). Smallpox is not completely out of the picture. After the 2001 attacks with anthrax, a strong paranoia of smallpox being used as another possible mean of bioterrorism has arisen(Oldstone, 32).
A person who has been infected by the disease may experience signs of fatigue, loss of appetite, fever, sore throat, swollen lymph nodes, and a red rash that appears blotchy. Generally the signs become present between ten and twenty-one days after the person has been exposed to and infected by the virus (Silverstein et al., 1998). This is what is known as the incubation period (Plum, J., 2001). The rash is most likely to begin on the chest, back, or the scalp, but will soon spread to the rest of the body. After a couple days of having physical evidence of the infection, the rash will s...
In the 1630s, another small pox epidemic broke out in what is modern day Massachusetts. After this epidemic, small pox would spread rapidly all across the New World killing off almost 90% of the Native peoples. It is said that this disease killed so many so rapidly that no one had the strength to even bury the dead. The Natives had such weak immune systems that sometimes the small pox
According to Linda Newson, “population size is critical for understanding the incidence of infection. Since endemic infections are characterized by latency and recurrence” . Here I will argue that highly dense population and slavery created conditions extremely favorable for the transmission of smallpox, and that it created huge impact on Spanish conquest. Did slavery and highly dense population increase in the spread of smallpox or it goes beyond these measures? The beginning of smallpox as a character illness is lost in ancient times. It is believed to have appeared in around 10,000BC, around the same time of the first agricultural settlement in northeastern Africa. “It appears conceivable that it spread from that point to India by method of aged Egyptian dealers. The earliest evidence of skin lesions resembling those of smallpox is found on faces of mummies from the time of the 18th and 20th Egyptian Dynasties (1570–1085 BC). Unknown in the New World, smallpox was introduced by the Spanish and Portuguese conquistadors.” (Edward
diseases in the world, and it was declared eradicated in 1980 (Smallpox). This and all the other
In the 1300s the plague spread so quickly in cities for many reasons. There were
The Demon in the Freezer by Richard Preston is an intriguing book that discusses the anthrax terrorist attacks after 9/11 and how smallpox might become a future bioterrorist threat to the world. The book provides a brief history of the smallpox disease including details of an outbreak in Germany in 1970. The disease was eradicated in 1979 due to the World Health Organization’s aggressive vaccine program. After the virus was no longer a treat the World Health Organization discontinued recommending the smallpox vaccination. In conjunction, inventory of the vaccine was decreased to save money. The virus was locked up in two labs, one in the United States and one in Russia. However, some feel the smallpox virus exists elsewhere. Dr. Peter Jahrling and a team of scientists at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland became concerned terrorists had access to the smallpox virus and planed to alter the strain to become more resistant. These doctors conducted smallpox experiments to discover more effective vaccines in case the virus were released. Preparedness for a major epidemic is discussed as well as the ease with which smallpox can be bioengineered.
In the book Pox Americana: The Great Smallpox Epidemic of 1775-82 by Elizabeth A. Fenn, the author provides a fresh outlook on the face of North America during the time of the American Revolution. Fenn provides the reader with a perspective of the American Revolution from the vantage point of the variola virus and its effect on the population of North America. Her thesis for the book is, “While colonial independence reshaped global politics forever, the contagion was the defining and determining event of the era for many residents of North America. With the exception of the war itself, epidemic smallpox was the greatest upheaval to afflict the continent in these years.” Fenn does not discount the war, but rather, provides more information about the era of the American Revolution and the role of smallpox within that time period. Considering the author’s argument, Fenn clarifies the diverse impact that smallpox had on North Americans depending on their race and social status during the American Revolution.
For approximately three-thousand years, smallpox has ravaged and plagued the four corners of the globe. In fact, in the 17 th and 18 th centuries, it was claimed to be the most infectious disease in the West, with an astounding 90% mortality rate in America. It wasn't until 1796, with English surgeon Edward Jenner's smallpox vaccination, that the world saw relief from this devastating virus. However, even with this inoculation in use, the world continued to witness death from both the virus and the vaccine. In the year 1966, it was estimated that 10-15 million infected citizens world wide had passed away from smallpox that year alone ( “History” 12). As a result of these devastating numbers, in the following year, 1967, the World Health Organization (W.H.O.) created a program to eradicate the smallpox virus. Ten years later, in 1977, the estimated 10-15 million cases had dwindled down to one; a man in Somalia. Three years later, W.H.O. officially announced that smallpox had been eradicated, leaving the only remaining virus cultures stored and guarded in laboratories in Russia and the United States. Inoculations ceased, smallpox epidemics were non-existent, and the virus was no longer a concern. In order to ensure complete eradication of this deadly virus, the W.H.O. insisted that the remaining smallpox cultures be destroyed by 1999 ( “Smallpox Eradication” 2). However, despite the W.H.O.'s recommendation, the remaining cultures continue to be contained and protected to this day, five years after the suggested date of elimination.
Smallpox is a disease from the variola virus. Smallpox has caused an estimated number of 300 million deaths in the 1900s alone. Smallpox is said to have been around since the ancient Egyptian times. The disease was eradicated in the late 20th century and two samples are still kept, one in U.S.A and one in Russia. Smallpox creates bumps and blisters all over the body and has been one of the most fatal epidemics the world has seen.