Tuskegee Case Study

The Tuskegee Study of Untreated Syphilis in the Untreated Male Negros made a distinct impact on the history of research. The study began in Mason County, Alabama in 1932 at the Tuskegee Institute. The goal was to learn about syphilis, and how the disease progressed with an emphasis on uneducated and illiterate African American males (Tuskegee University, n.d). There were 600 participants involved; 399 with documented cases of syphilis, and 201 control group members without syphilis (Center for Disease Control and Prevention, 2013). Researchers informed the participants that they had “bad blood,” never informing them that they were infected with syphilis (Tuskegee University, n.d). To encourage the men to participate in the study they provided free medical care, transportation, meals on the days they were being examined, and burial insurance (Tuskegee University, n.d). When the study began no reliable treatments were available.
The study was based on the Oslo study, which stated that the current treatments of mercurial ointment were of no benefit, and that going untreated was more beneficial for the patient in the end (Brandt, 1978). Participants were given full physical exams, radiographs, and lumbar punctures that were conducted by the United States Public Health Services (Brandt, 1978). To guarantee that the men would show up for the lumbar puncture, researchers sent a letter to the participant titled, “Last Chance for Special Free Treatment,” (Brandt, 1978). Research continued, and in 1945, penicillin became approved to treat syphilis (Center for Disease Control and Prevention, 2013). The USPHS could have incorporated this treatment into their study, but chose to prevent the men from getting treatment, and never informed the p...

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... & Human Services, 1979).
After the conclusion of the Tuskegee Study, research found that many African American individuals were hesitant to participate in biomedical research (Davis, Green, & Katz, 2012). Researchers also found that African Americans have a distrust towards and suspicion of other health education programs such as the HIV/AIDS prevention programs. This is due to the similar methods used to select the participants in these programs as compared to the Tuskegee Study (Thomas & S.B., 1991).
The Tuskegee Syphilis Study had and will continue to have lasting effects on the research community. Fortunately, some of these effects have improved how research is currently being conducted. To continue to build upon these improvements, researchers need to find ways to make all individuals comfortable and secure with the research in which they are participating.