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cause and effect of tuberculosis
an essay on tuberculosis
background of tuberculosis
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Tuberculosis or TB, referred to by some as the White death due to the epidemic that arose in Europe that lasted two hundred years, is usually caused by in humans by a microorganism by substrains of Mycobacterium tuberculosis. It’s hard to determine the exact years in which TB first infected humans, but since the disease leaves traces on the bone in can be found in archeological record and it is believed to go all the way back to the B.C. era. Although it is hard to tell if the bone damage was truly from TB, there is research that shows that it has been around since the 17th and 18th centuries with a high number of incidences of TB, and in 1882 Dr. Robert Koch announced that his discovery of the causing factor of TB, which is Mycobacterium tuberculosis. A tuberculosis bacterium is spread through the air by an infected person speaking, coughing, or sneezing. Due to the fact the bacteria is protected by a waxy cell all, the body’s defense takes weeks to develop any kind of immunity and it allows the bacteria to exponentially multiply freely within the body. If TB it’s left untreated it will eat rapidly through many tissues, usually beginning with the lungs, lymph nodes, and kidneys. As the infection spreads to the lungs, it causes a cough and fluid between the chest wall and lungs, which leads to chest pains, severe shortness of breath, and potential heart failure. TB also infects bones and joints that can produce arthritis like pain and characteristic bone damage. Another possibility is that it may affect the fluid around the brain, causing meningitis, which can lead to fever, drowsiness, and eventually coma and death (Wingerson, 2009). Tuberculosis becomes its most deadly in very crowded and unsanitary conditions, which was the case in the earlier years of Europe and North America, which causes the number of infected to rise once one person is exposed to TB. Now in
The lungs are the organs responsible for the exchange of oxygen and carbon dioxide between the air and the blood via the bronchial tree. Tuberculosis (TB) is a granulomatous disease which primarily infects the lungs but can spread to other vital organs. It is caused by bacteria called Myobacterium tuberculosis and if went untreated, can be fatal. TB is spread through the air when a person who is infected coughs or sneezes and a person nearby breathes the air. People who have been diagnosed with HIV are at a higher risk of contracting TB since their immune systems are weaker. Other risk factors include having diabetes, use of alcohol and drugs. In this paper I will discuss the normal functions and anatomy of the lungs and how TB effects these functions.
An estimated one third of the world 's population is infected with Mycobacterium tuberculosis. In 2012 there were 9,975 cases of TB reported and of those cases 28% where Hispanic or Latino. This respiratory disease is the most common in the lungs (World Health Organization, 2014). The brain which causes tuberculosis meningitis, genitourinary TB, gastrointestinal TB, tuberculosis lymphadenitis, cutaneous TB, uterus ovarian TB and Osteo- articular skeletal bone and joints are also parts of the body that are affected (Article base, 2008). Symptoms of TB are chills, fever, night sweats, hemoptysis, cough lasting more than 3 weeks, chest pains, and weight loss (Tuberculosis, 2014). Transmission of TB is through a sneeze, a cough, speaking, or singing in which the person has the
Tuberculosis is a contagious airborne disease that affects the lungs of humans and some animals i.e. cattle. If tuberculosis is left untreated and allowed to spread, it can then also affect the brain, kidneys, spine or other organ systems. As tuberculosis strikes the lungs a hole can develop which can cause an accumulation of air or fluid between the chest wall and lungs. This causes one of many tuberculosis symptoms: chest pain, and shortness of breath. (See fig.2) Infections can erode a blood vessel and the patient can bleed to death, or they can slowly suffocate as lungs become filled with tubercles.4
The bacteria are gasped in a process of air and overcome by alveolar macrophages. In some cases the bacteria’s are able to reproduce and the new pledge can harm the victim. Furthermore, Tuberculosis spreads when the mycobacterial enters alveolar mycobacterial.
Tuberculosis is an air-borne disease, hence, it can be passed from an infected person to a healthy individual through coughing, sneezing and other salivary secretions. Tuberculosis is caused by the transfer of Mycobacteriun Tuberculosis (M. Tuberculosis) also known as Tubercle Bacillus, a small particle of 1-5 microns in diameter, due to the small size, when an infected person sneezes or coughs, about 3,000 particles are expelled. M. Tuberculosis responsible for tuberculosis is able to stay in the air for a long period of time (about 6hoursAnother way of acquiring Tuberculosis is by drinking unpasteurized milk, milk straight from cow, although this is not a common mode of transmission, it can be found in rural areas. Ingestion of contaminated cow milk transmits Mycobacterium Bovis, the animal form which is still potent enough to cause tuberculosis in humans. ). Tuberculosis transmission is affected by exposure, socioeconomic status of person, proximity, immune status of uninfected individual (%&&%&? CDC).
Tuberculosis is disease caused by a bacterium called Mycobacterium tuberculosis. Usually bacteria attacks lungs but TB bacteria can attack any parts of the body such as brain, kidney, and spine. It can spread through the lymph node and blood stream to any organ. Usually it is seen in the lungs. If it is not treated accordingly, it can be deadly. One of the leading causes of death in the United States was tuberculosis. Everyone who infected with TB bacteria not get sick. There are two TB conditions stand. They are latent TB infection and TB disease. In latent TB infection, people do not get sick but TB bacteria can live in you. People with latent TB infection cannot spread the bacteria to others nor are they infectious. If the bacteria is active and multiply, the person has TB disease. If a person has TB disease, their immune system cannot stop the bacteria become active. People with TB disease get sick and they are able to spread the bacteria to others.
TB is a disease that can cause a serious illness and can damage a person's
Throughout many years tuberculosis has atrociously affected the lives of many people. Many have suffered a horrible death due to this horrid disease. Tuberculosis is a highly contagious disease due to mycobacterium tuberculosis, which initiated about one hundred fifty million years ago. Skeletal abnormalities typical for tuberculosis were found in Egyptian mummies back in 2400 BC. In ancient Greece the Greeks seemed very familiar with tuberculosis only they called it Phtisis. Many years later a disease that was called “ scrofula” was described to be a certain form of tuberculosis. It was referred to as “king’s evil” in England and France, and they believed it could be cured by a royal touch. This practice was put to an end in the year 1714.
TB is a significant zoonotic disease (a disease of animals which can also infect humans).
Mycobacterium tuberculosis (MTB) is the main causative organism which attacks the lungs but can also infect other organs of the body. M.tuberculosis is an intracellular pathogen that is highly adapted to human.7The bacterium spread primarily through aerosolized infectious particles generated from coughing and sneezing by individuals with pulmonary tuberculosis and less commonly via skin wounds 8. The most important factors influencing the current TB epidemic in resource poor setting are closely related to malnutrition, overcrowded living conditions and lack of access to free or affordable health care services.9
Throughout the industrial revolution, tuberculosis or as it is known for short “TB” was also a major killer for the population. Tuberculosis is an infectious disease which is caused by various types of micro bacteria. Tuberculosis affects ones lungs, but it doesn’t stop there, it can also spread to various parts of one’s body and causes tremendous damages. Due to the great number of lives the tuberculosis disease took during the industrial revolution, many of the people gave it a specific name, relatable to the black plague, only they called it “The white death” a metaphorical name for the disease. The poor sanitary jobs made tuberculosis very easy to attract.
Tuberculosis or TB is an airborn infection caused by inhaled droplets that contain mycobacterium tuberculosis. When infected, the body will initiate a cell-mediated hypersensitivity response which leads to formation of lesion or cavity and positive reaction to tuberculin skin test (Kaufman, 2011). People who have been infected with mycobacteria will have a positive skin test, but only ones who have active TB will show signs and symtoms. Basic signs and symptoms include low grade fever, cough with hemoptysis, and tachypnea. They may also show pleuristic chest pain, dyspnea, progressive weight loss, fatigue and malaise (Porth, 2011).
Mycobacterium tuberculosis has been present in the human population for thousands of years; fragments of the spinal column from Egyptian mummies from 2400 BCE show definite pathological signs of tubercular decay. Called "consumption," tuberculosis was recognized as the leading cause of mortality by 1650. Using a new staining technique, Robert Koch identified the bacterium responsible for causing consumption in 1882. While scientists finally had a target for fighting the disease, they did not have the means to treat patients; the spread of infection was controlled only by attempting to isolate patients. At the turn of the twentieth century, more than 80% of the population in the United States was infected before age 20, and tuberculosis was still the leading cause of death. The production of antibiotics in the 1940’s allowed physicians to begin effectively treating patients, leading to huge drops in the death rate of the disease. Tuberculosis is still a major cause of mortality in young adults worldwide, but is less of a problem in developed countries.
Active tuberculosis only develops in about 10% of infected persons, remaining dormant in the rest; although the latent infection may later progress to active disease years later, especially in immune-compromised individuals. 9 Infection by MTBC may involve any organ of the body, but clinical presentation is most common in the lungs (pulmonary TB). General symptoms include fever, loss of appetite, weight loss, fatigue and severe cough with bloody sputum (hemoptysis) which may lead to death if untreated. 10 Mortality rates without treatment are high: in a study of natural history of TB in HIV-negative patients, 70% died within 10 years. 11 Tuberculosis remains a major health problem in the world...
8.) Tuberculosis. 21 Dec 2004 Mayo Foundation for Medical Education and Research (MFMER). 16 July 2006 .