Summary: Background and objective. Tumor heterogeneity is shown to be related to clinical outcome in cancer patients. The concept of a small subset of cancer stem cells being responsible for tumor relapse and metastasis comes out as a promising strategy for targeted cancer therapy. However, cancer stem cells are not easy to identify and isolate. The aim of this study was to determine the putative colon cancer stem cell subsets in human colon cancer cell lines HCT116 and HT29, which differ in their aggressiveness and differentiation capacity.
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These oncogenes cause cancer because they do not allow the cells to self destruct or become epistatic. There have been several research projects which have been testing epistatis. Transfecting DNA To perform the experiments for this re... ... middle of paper ... ...wth of both normal and malignant cells. The limited research that has been performed using these cells has yielded contradictory results: some results say that the alpha5beta1 integrins destroy cancer cells, other results have shown that cell division and other necessary cell functions have been encouraged by the integrin. But the research has predominantly shown that the results of the expression of alpha5beta1 integrins yield beneficial results in terms of cancer tumor reduction.
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