The Neurobiological Factors Associated with Depression
Depression is a mood disorder that affects approximately ten percent of men and nearly twenty-five percent of women at least once in their lifetime (1). There are several types of clinical depression, such as unipolar depression and bipolar depression. Unipolar depression consists of primarily depressive states while bipolar depression involves a fluctuation between states of depression and mania (2). Some of the most common symptoms of depression include excessive feelings of sadness, guilt, or worthlessness, a significant change in appetite, insomnia or hypersomnia, energy loss, thoughts or attempts of suicide, and anhedonia (3), (4). While the symptoms of depression are understood fairly well, how the exact causes of the disorder interact in the development of depression remain somewhat of a mystery.
There are several biological factors that may contribute to the increased susceptibility to depression. Genetic links have been made as the result of twin studies suggesting that family members of depressed patients are more likely to be depressed or to develop depression than the general population. However, it is important to note that these results may be due to the similar environments of twins rather than genetic influence (5). Consequently, studies comparing twins who were reared apart have been conducted and the data suggest that the concordance rates for twins reared together or apart is nearly identical, although the rate is slightly lower for twins reared apart. This suggests that while the environment does play an important role in the development of depressive symptoms, genetic influences are also important (6). In addition, other genetic studies have sugges...
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8) Carlson, Neil. Physiology of Behavior. Massachusetts: Allyn and Bacon, 2001.
9)Carol Hart, Secrets of Serotonin, Chapter 2, Information about Serotonin
http://nasw.org/users/twoharts/serotonin.htm
10) Depression: Beyond the Catecholamine Theory of Mood, A good overview of depression
http://salmon.psy.plym.ac.uk/year3/psy337DepressionTheory/PSY337DepressionTheory.htm#catheoryofmood
11)The Chemistry of Depression
http://depression.about.com/cs/brainchem101/a/brainchemistry.htm
12) Gilbert, Paul. Overcoming Depression: A Step-by-Step Approach to Gaining Control Over Depression. Oxford: Oxford University Press, 2001.
13)Behavior: The Neurobiology of Depression, An interesting article by a psychiatrist at the University of Michigan
http://www.thedoctorwillseeyounow.com/articles/behavior/depressn_5/
According to the reorganization notion of neuroplasticity, experiences and events can carve out new synaptic patterns in one’s brain, which alter brain function and in turn the biological factors that bring about depression. This suggests that social and biological factors of depression are intertwined and interdependent on one another. As a result, in order to understand complex psychological diseases such as depression, we must consider both social and biological factors concurrently and with equal
This paper will focus on depressive disorders, and it will describe what they are, how they manifest themselves, what causes them and/or what makes certain individuals susceptible to the disorder as compared to others. This piece will also describe the most common treatment practices, and the effectiveness of these treatments. It will conclude by offering some testimonials from individuals who suffer from depressive disorders as well as some additional commentary about depressive disorders and their implications/challenges.
Many people have heard the term cerebral palsy and may have a personal perception about the appearance and effects of this
Today, Americans seem to believe that olden-day slavery is the only possible form of slavery, but they do not see the horrors that go behind all the different types of modern-day slavery around the world. The most common form of slavery today is called debt-bondage, or bonded labor (Meyer, pg. 9). People who are in desperate need of money look for people who can help pay off their debt. Workers receive the pay in the advance, and then do not know how much work they will have to do in order to pay off their debt; therefore, they can never get free of their debt (Meyer, pg
Andrews N, Strangers to Justice No Longer: The Reversal of the Privity Rule under the Contracts (Rights of Third Parties) Act 1999 (2001) 60 The Cambridge Law Journal 353
Having evaluated the current state of English contract law, mainly made up of piecemeal solutions, it can be seen that despite being satisfactory and doing its job, there still remain gaps within the law of contract where unfairness is not dealt with. Moreover, due to the ad hoc nature of those piecemeal solutions, the latter have often produced inconsistent justice and have manifested cases of unfairness. Hence, “a relatively small number of respected Justices have endeavored to draw attention to the fact that the application of a general principle might be useful and even necessary in English law.”
As a people who were born free, futures ripe with opportunities and choices, it’s hard for most in American society to truly imagine slavery. It’s a horrific concept that is ingrained into childrens heads and then thought of as only an idea in a history class, but sadly, the past doesn’t seem to always stay in the past. Many forms of slavery that share a plethora of traits with slavery found back in the times of the civil war, are still very prevalent in the world today, domestic work and exploitation being a very huge problem in several countries.
Depression is an illness within itself that affects the “whole body”. (Staywell,1998) The body, feelings, thoughts, and behavior are all immensely altered when someone is depressed. It is not a sign of personal weakness, or a condition that can be wished or willed away. For some people depression is just temporary, but for others it can last for weeks, months and even years.
Many twin studies have also shown results that genetically identical twins (MZ) have a greater number of inheriting depression than non-identical twins (DZ). For instance an experiment carried out by Prince in 1968 expected that MZ twins would have a higher concordance for depression compared to DZ twins. Results found were that the MZ twins who were raised in the same environment/family showed a concordance of 68% and DZ twins had a lower concordance of 28% for bipolar disorder only. This is evidenc...
Much can happen in a matter of minutes; a man can go from thinking he is happy to thinking his life is falling apart, or can change from hating someone to loving them. These experiences sound outlandish, but they happened to Guy Montag, the main character in Ray Bradbury’s Fahrenheit 451, and Winston Smith, the main character in George Orwell’s 1984. These two dystopian novels are about the characters discovering major problems in their societies, and then trying to fix them. Montag lives in a society where television controls people’s lives and books have become illegal. On the other hand Smith lives in Oceania, a territory led by a totalitarian regime. This regime is headed by Big Brother and is referred to as the Party. By examining Fahrenheit 451 and 1984, it is seen, not only through the dehumanized nature of society, but also through the theme of lies and manipulation that both Orwell and Bradbury wish to warn of a horrifying future society.
Depression is one of the most widespread mental disorders globally, affecting more that 350 million people of all ages. It is characterized by disturbed sleep, loss of appetite, sadness, poor concentration and feelings of guilt. There are various types of depression which are long lasting, and other types which are constantly reoccurring (World Health Organisation , 2012). Severe symptoms of depression that inhibit the ability to work, sleep and eat is categorised as major depression, this form of depression can occur once in a lifetime, however in some circumstances it may occur more often. Persistent depressive disorder can last up to 2 years; symptoms may resemble major depression along with episodes of less severe symptoms. Psychotic depression is a form of severe depression when a person begins to hallucinate and have delusions. Postpartum depression is experienced by women after birth, physical and hormonal changes can lead to depression. Seasonal affective depression (SAD) usually occurs during winter due to less sunlight. Another major type of depression is bipolar disorder which is categorized as changes in mood, for instance extreme high moods to extreme low moods (National Institute of Mental Health, 2011). The prevalence of depression was analysed in 8449 individuals aged between 15 and 40, results showed that depression was commonly found in white males and females than in black and Mexican male and females (Stephanie et al, 2005).
The biological influences associated with depression include genes, chemical imbalance, and or damage to the anatomy of the brain. For example, genes are the personal blueprint of every individual, which maps out what a person is likely to inherit from generation to generation. These inherited gens predispose a person to inherit certain personality traits, physical features, medical and mental health condition such as depression. However, if these inherited genes do not become active by an environmental influence such as the loss of a loved one or a job, there is no guarantee that a condition will take place (NIMH, 1998). In a study by Sullivan, Neale, and Kendler (2000), the implications of genetic influences is evident that familial aggregation (x2 = 97.7, df = 1, p > 0.00005) runs in biological families (first-degree relatives such as parents and children) with major depression. In addition, the twin studies indicate a higher genetic influence in identical twin (who share identical genes) a...
Neyfakh, Leon. "Why We Can't Stop." Boston Globe. 06 Oct 2013: K.1. SIRS Issues Researcher. Web. 15 Dec 2013.ssues Researcher. Web. 07 Nov 2013.
Depression is much more common than most people think. Because it is essentially an invisible illness and is largely in the mind, it is difficult to correctly diagnose it and most people suffer for months, years, or even decades with depression. The Merriam-Webster Dictionary defines depression as “a mood disorder marked especially by sadness, inactivity, difficulty with thinking and concentration, a significant increase or decrease in appetite and time spent sleeping, feelings of dejection and hopelessness, and sometimes suicidal thoughts or an attempt to commit suicide.” Most medical definitions are able to explain what happens and why it does, but after carefully examining this one, we only notice that it explains what happens, but not why. Usually, the symptoms of an illness are...
Austria (z Stubenrauch, Commentar zum iisterreichischen allgemeinen biirgerlichen Gesetzbuche (6th ed.) sec. 86I, p. 5)