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Who discovered structure of DNA
Crick and Watson, "A Blueprint for Life
Rosalind franklin discovery of dna essay
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For a long time, scientists have been researching about DNA and its structures. DNA is strongly related to genetics and how living things perform. Two very intelligent scientists, James Watson and Francis Crick, have made history in Biochemistry when they discovered the structure of DNA. The central idea of this paper is researching the history of DNA structure discovery and about why it is very important. Discovery of DNA structure is very important because DNA is what makes all living things behave the way they do and studying DNA also means learning why living things act this way. DNA structure is a key part of organism traits, behavior, and development of all living organisms. For some background information, DNA stands for deoxyribonucleic …show more content…
James Watson and Francis Crick were the two main scientists who discovered the double helix, the main structure of DNA. Two other scientists, named Rosalind Franklin and Maurice Wilkins, also helped and contributed along with James Watson and Francis Crick. However, they weren’t as famous because many people believed that they didn’t play as big of a role in the discovery. These scientists were trying to discover the structure of DNA. Their first discovery was the double helix, and Friedrich Miescher, a swiss chemist, discovered “nuclein” inside nuclei of white blood cells, which its name later changed to nucleic acid and then deoxyribonucleic acid, and abbreviated as DNA. Phoebus Levene, a Russian biochemist, discovered the makeup of nucleotides (phosphate and sugar bases) and all the different parts of both DNA (deoxyribose) and RNA (ribose). James Watson and Francis Crick used this information to determine how all of this DNA was made up and formed. They found that the basic molecule of DNA is called the double helix, and how each of the parts of the double helix were connected (the sugar-phosphate bases acted as the sides of the ladder or the stair rails and the nitrogen bases were the steps) and how they each were arranged. They also discovered about the four nitrogen bases, their shapes, and how you can re-organize them in different orders, but due to their shapes, A and T must be connected to each other and the same goes for G and C. DNA was discovered in the 1800s by various scientists, but James Watson and Francis Crick didn’t determine what the structure of DNA was until 1953. James Watson and Francis Crick met at Cambridge University and met Rosalind Franklin and Maurice Wilkins in London, England. The way that Watson and Crick discovered the structure is that they found that the shape of each nitrogen base and used reasoning to determine that G must fasten
The book Rosalind Franklin and DNA is a biography of Rosalind Franklin written by a British journalist and close friend of hers, Anne Sayre to reveal the true personality of Rosalind Franklin in contradiction to the fallacious character portrayed by James Watson in his personal account of The Double Helix. This book was undertaken to refute Franklin’s distorted portrait from abnormal feminist into rational, perfectionist and talented ‘women’ scientist. She begins by introducing her strong background, curious childhood, dedicated education, generous nature and most importantly how she was brought up in a favorable environment of distinctive Angelo-Jewish family, who identified and cultivated her talents and developed her in a person with full capacity for commitment. In this book, despite admiring the geniuses of Watson in depicting and picking out small information, connecting points and the kind of abilities he possessed was perfectly factitive with Crick that Rosalind and Gosling lacked however, she constantly tries to put the Rosalind’s side of story in picture which she believes was minimized in The Double Helix by Watson and correct her character that distorted in public eye.
How Watson and Crick’s Discovery of the Structure of DNA Influenced American Industries and Scientific Development in the United States
Everyone is familiar with the blue print, or book, of life. Deoxyribonucleic Acid, or DNA, for short. After all, every single cell of our trillion possesses a double-membraned blob (nucleus) just to house it. As with anyone who ever studied genetics, pilgrims to the Delphic oracle in ancient Greece always discovered something profound about them when they inquired of it-but rarely that which they assumed to have learned in the first place. The Greek king Croesus once asked the oracle if he should commence a war with a neighboring kingdom only to be told “You will destroy a great empire”. He did only his own. Likewise, DNA speaks in code with the occasional satirical message. Unlike Delphi, our oracle still speaks, and louder than ever. From
They’re idea was to show that DNA had to copy itself during the cell division process. The point of this idea was that the DNA molecule make exact replicas of itself in order to pass to its “daughter cells”. Though the two groups were working separately, Watson saw the work that Franklin was doing in her lab, from her images they deduced that DNA might consist of two strands of DNA that were connected and shaped much like a spiral staircase. From seeing the images they decided on a model approach to prove their theory. They designed many variations all to no avail until they stumbled upon the right connects. Discovering that DNA was less like a Spiral staircase and more like a twisted ladder, they finally had the right configuration, a double helix. At this point of their experiment they were only missing one final clue. They needed to know how the different components of DNA bonded together. They found this answer with the help of an American named Jerry Donohue, a chemist who found that hydrogen bonding was the key. The hydrogen allowed the different components to bond together from a position on the inside to the structure and phosphates worked from the outside of the structure. Once all the pieces were discovered, Watson and Crick could finally construct their final product and write their paper. They noted the way DNA was constructed that it spoke of
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
The origins of DNA were first discovered during 1857 by Gregor Mendel the "Father of Genetics”, whom was performing an experiment of genetics with pea plants, and would provide a basic foundation towards DNA and Genetics. Friedrich Miescher and Richard Altmann in 1869 were also part of the first people to discover DNA. While testing some sperm of a salmon, they discover a strange substance that they would name as "nuclein", which is known as DNA. This new form of "nuclein" (DNA) would be found to only exist in chromosomes. Frederick Griffith, a researcher, found the basis on DNA, from a molecule inheritance experiment involving mice and two types of pneumonia. His findings were that, when virulent disease is heated up (to kill) and is injected into a mouse, the mouse survives. Unlike the second mouse that has been injected with non-virulent disease and virulent disease (that had been heated and killed) is killed. This would be caused by an inheritance of molecule (transformation) of virulent bacteria passing on a characteristic to the non-virulent. DNA findings would continue to be tested and tried to better understand how DNA works.
The discovery of DNA is quite mind-blowing. Rumor has it that James Watson and Francis Crick discovered DNA, but they actually did not. It all started in 1869, with a well-known German biochemist named Friedrich Miescher who isolated, analyzed, and recognized a distinctive macromolecule known as DNA. Years later, on the morning of February 28, 1953, Watson and Crick came into the picture, as they announced that they “had discovered the secret of life” (Markel 2013). Their discovery of the double helix made them publish a paper in the 1953 issue of Nature, describing the structure of DNA, which resulted them to receive the Nobel Prize in 1962.
Genetics relies on chemistry to explain phenomena related to the field. The structure of DNA relies on chemistry. In fact, when James Watson and Francis Crick discovered the structure of DNA, they did so by building models based on the laws of chemistry. Chemistry also relates heavily to the structure and function of one of the main products of DNA: protein.
James D. Watson is a molecular biologist, geneticist and zoologist. He is well known as one of the two men who discovered DNA. The other man who helped discover DNA is Francis Crick. Francis is a biologist, neurologist and a biophysicist.
Epigenetics, which also means “above genetics”, is defined as the study of chemical reactions that take place in the organism as this one grows and develop. This chemical reaction activate and deactivate at certain time and location some parts of the genome. The video resulted extremely interesting because it shows how our body react to the epigenomes and how important is our lifestyle to our health and for the health of our next generations.
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
The Double Helix tells a tale of fierce competition, perseverance, and scientific innovation as we follow James Watson and his cohort Francis Crick on their quest to discover the secret to life, the structure of deoxyribonucleic acid. Although already fascinated with DNA, Watson struggled with finding chemistry exciting enough to learn it in depth. He had studied birds in college and thereby managed to avoid any formal chemistry or physics courses. As he later pursued a PhD in biochemistry, he realized he could put it off no longer and attempted to learn organic chemistry at Indiana University. However, after a mishap in the lab, he was encouraged instead to study nucleic acid chemistry with Herman Kalckar in Copenhagen. There, his mind strayed from his work and he began doing unauthorized research in the lab of Ole Maaløe, studying phages. Herman stopped teaching Watson after going through a divorce with his wife, and sent Watson off to a scientific conference in Naples. Although he was bored by many of the lectures, Maurice Wilkins’s talk about X-ray diffraction fascinated Watson. He was struck by an X-ray diffraction picture of DNA that Maurice presented and was determined to study the acid. He later got to know more about Maurice’s colleague, Rosalind Franklin, who was proud, stubborn, and very difficult to work with. Watson greatly admired the lecture given by the renowned Linus Pauling, who had discovered the structure of the alpha-helix and was thought of as the leader in DNA research in the scientific world.
Simply put, DNA contains the instructions needed for an organism to develop, survive, and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientists use the term “double helix” to describe DNA’s winding, two-stranded chemical structure.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).
Science and Technology has been around from the beginning of time. It evolved from the everyday efforts of people trying to improve their way of life. Throughout history, humankind has developed and utilized tools, machines, and techniques without understanding how or why they worked or comprehending their physical or chemical composition. Before we go any further a definition has to be given for both Science and Technology because they are both different in their own right even though the two are almost indistinguishable. According to the Oxford Dictionary Technology can be defined as the knowledge or use of the mechanical arts and applied sciences, while Science can be defined as the branch of knowledge involving systematized observation and experiment. Science can be further divided into three separate categories; Pure, Applied and Natural Sciences. In addition technology is often defined as applied science, it is simply the application of scientific knowledge to achieve a specific human purpose, however, historical evidence suggests technology is a product of science.