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Recommended: Tetanus patient
The Disease Tetanus
Tetanus: acute infectious disease of the central nervous system caused by the toxins of Clostridium Tetani.
This disease, often referred to as lockjaw, is a very serious illness. It is found on almost anything, but is not a common illness. This is because the disease must be transported to the lower layers of the skin and must be sealed there to incubate and grow. Tetanus causes the muscles in the body, often the arms and facial region, to contract but not have the ability to relax. It's a state of rigamortis while the person infected is still alive. The tetanus toxin is one of the most potent poisons known, yet is found in your body right now. It is often located in feces and soil, but the intestinal enzymes destroy the toxin. The mortality rate for a person infected is about 40% and that number almost doubles if the person is very young or elderly. The muscles in the chest and abdomen eventually tense up and cause the person to either stop breathing, or stops their heart. So what does a person do to prevent such an illness form happening to them? The first thing to do is get a booster shot or vaccination from the tetanus toxin. With that in place, the chance of tetanus is almost 1%. There is still a chance that the person will become infected though. So treatment has been made possible but it is still in developmental stages. The first thing that is done is the body is treated with a sort of tetanus antitoxin in conjunction with human immune globulin. This, plus a percentage of dead Tetani, cause the body to create cells capable of eliminating the toxin found outside of the intestine. Deep puncture wounds are the main source of entry for tetanus. The toxin, known as tetanospasmin, travels to the brain through the blood. If tetanus is in the body for more than 15 days, and the body registers this, then the treatment is almost useless but may cause comfort. Often, a patient will have to have an IV of penicillin and sometimes, the tissue is removed from the body. For comfort, the doctors may also give muscle relaxants. The booster shot is given for 4 years to children from age two to age six and is known as a DPT (diphtheria, pertussis, and tetanus) vaccine.
E. Coli 0157, written by Mary Heersink, is a nerve-racking, adrenaline-filled story of a mother's experience with a then unknown deadly bacteria. The book brings up many reactions in its readers, especially the questioning of the practice of doctors in hospitals. The reader's knowledge base of scientific procedures in emergency centers was widened as well as the knowledge of how to the human body reacts to different agents in its system.
Clostridium difficile, otherwise known as C. diff, is a species of spore-forming, anaerobic, gram-positive bacteria that is known to cause watery diarrhea. 1 The genus name, Clostridium refers to the spindle shape of the organism while Difficile means difficult in Latin due to the fact that this organism thrives in unfavorable conditions and is very difficult to isolate.4 The incidence of getting CDI has increased over the years due to new strains of increased toxin production of the bacteria and increased resistance to antibiotics.2 It is a gastrointestinal infection, and the most common cause of infectious diarrhea.1 C. difficile was first identified in the feces of healthy newborns back in the 1930’s and by 1935, it was considered normal flora. 2 During 1974, researchers conducted that about 21% of patients that were treated with an antibiotic called clindamyacin reported diarrhea and about 10% of them reported to have conducted pseudomembranous colitis as a side effect of this treatment. 2 It was in 1978 where C. diff had been known to cause anti-biotic associated diarrhea and pseudomembranous colitis. 2 It is known to form spores that resist many disinfectants; it also survives for several months on different surfaces.1 It is a common form of a nosocomial infection and the prevalence of becoming infected with C. diff is about 0-15% in a health care setting. 3 The spores survive well in environments such as soil, water and animals and is distributed worldwide. 4 CDI produces two toxins (Toxin A and B), which are cytotoxic and cause tissue necrosis.4
The disease, botulism, which is caused by Clostridium botulinium, is an emerging infectious disease. Clostridium botulinium is a bacterium that produces a neurotoxin that causes botulism. The bacterium is spore-forming, and anaerobic, meaning it does not need oxygen to grow. There are three main types of illnesses that Clostridium botulinium typically cause: Food-borne botulism, infant botulism, and wound botulism. Unbeknownst to common knowledge, infant botulism is the most common form of the disease, consisting of seventy-five percent of the reported cases of the disease (Chan-Tack, & Bartlett, 2010).
Botulism is a rare but very serious paralytic illness that is caused by the botulinum toxin that is produced by the bacterium Clostridium botulinum. C. botulinum is a gram positive, anaerobic, spore forming bacterium that is naturally occurring in soil. Botulism dates back to the eighteenth century when the first food borne botulism was documented. During this time many people were doing home fermented sausages and this was thought to be the cause of botulism. This is how the toxin got its name since “Botulism” in Latin comes from “botulus” which means sausage. E. van Ermengen was the first to discover the microbe in 1897 after there was a food borne outbreak in Ellezelles, Belgium. To date there are six forms of botulism but only two forms were known until the twentieth century which were food borne and wound botulism. The first type of botulism is food borne which is a result of ingesting food that contains the pre-form toxin. Some foods that this typically occurs in are home canned vegetables, cured pork and ham and smoked or raw fish. Wound botulism is the result of C. botulinum spores growing in a contaminated wound with in vivo production. Most people that get wound botulism usually have deep and contained avascular areas and many people also had compound fractures. Wound botulism is on the rise in the U.S. because of the use of illicit drugs, “the majority were linked to injectable drug use, particularly with so-called ‘black tar heroin’ and others with nasal or sinus lesions due to chronic cocaine sniffing.” (CDC website) Another form of botulism is infant botulism. This is caused from the endogenous production of toxin germinating spores of C. botulinum in the intestines of the infants. Also feeding an infant...
Botulism is a rare but serious condition caused by toxins from bacteria called Clostridium botulinum (Botulism, 2012). Botulinum neurotoxins or, as abbreviated BoNTs, are some of the most extreme and dangerous substances that are known to the human population. There are 3 forms of botulism which include infant botulism, food borne botulism and wound botulism (Botulism, 2012). This specific genus of Clostridium causes “flaccid muscle paralysis by blocking acetylcholine release at nerve muscle junctions through a specific and exclusive endopeptidase activity against SNARE proteins of presynaptic exocytosis machinery” (Kukreja & Singh, 2005).
Among hospitalized patients around the world, Clostridium difficile is the primary source of infectious diarrhea. Previously, continuously unbalanced intestinal microbiota, usually due to antimicrobials, was deemed a precondition for developing the infection. However, recently, there have been alterations in the biology from virtually infecting the elderly population exclusively, wherein the microbiota in their guts have been interrupted by antimicrobials, to currently infecting individuals within of all age groups displaying no recent antimicrobial use. Furthermore, recent reports have confirmed critical occurrences among groups previously assumed to be of minimal risk—pregnant women, children, and individuals with no previous exposure to antimicrobials, for instance. Unfortunately, this Gram-positive, toxin-producing anaerobic bacterium is estimated to cost US critical care facilities $800 million per year at present, suggesting the need for effective measures to eliminate this nosocomial infection (Yakob, Riley, Paterson, & Clements, 2013).
Vaccine safety is one of the most controversial topics in today’s public discourse. Everyone has heard of them, but few know why they are so encouraged. A vaccine contains a weak or dead version of a microbe. This creates a small scale invasion of the immune system, which activates cells to destroy the microbe. Once these cells have been made they are always there to provide protection. This protection is immunity, for those cells are then able to recognize any live version of the same microbe and attack it immediately. This can save lives but also be dangerous, vaccines carry many other components which can cause side effects. These could be simple adverse effects such as a small cold or, in the rare case,
“Vaccinations are causing a major upsurge in childhood diseases, adult maladies, and even deadly ailments such as Gulf War Syndrome and Lou Gehrig’s disease” (Blaylock). Every now and then an individual’s doctor calls telling them about the latest vaccine they should receive. The person immediately schedules a time to come in and get it done. But do they even give a second thought about it? Have they ever thought that maybe they do not need another vaccination? Many people have not taken the time to seriously think about the process of immunization. The truth is, there are many dangers that the average person should be unaware of. Rarely do vaccines actually accomplish what the public has been told. In fact, a lot of vaccines contain harmful substances that have been linked to disorders such as autism. The lack of education and dishonesty from doctors are putting people in danger of health problems without even realizing. Many parents feel obligated for their children to get vaccinated because of school, not knowing they have the alternative option of refusing immunization.
Tuberculosis or TB, referred to by some as the White death due to the epidemic that arose in Europe that lasted two hundred years, is usually caused by in humans by a microorganism by substrains of Mycobacterium tuberculosis. It’s hard to determine the exact years in which TB first infected humans, but since the disease leaves traces on the bone in can be found in archeological record and it is believed to go all the way back to the B.C. era. Although it is hard to tell if the bone damage was truly from TB, there is research that shows that it has been around since the 17th and 18th centuries with a high number of incidences of TB, and in 1882 Dr. Robert Koch announced that his discovery of the causing factor of TB, which is Mycobacterium tuberculosis. A tuberculosis bacterium is spread through the air by an infected person speaking, coughing, or sneezing. Due to the fact the bacteria is protected by a waxy cell all, the body’s defense takes weeks to develop any kind of immunity and it allows the bacteria to exponentially multiply freely within the body. If TB it’s left untreated it will eat rapidly through many tissues, usually beginning with the lungs, lymph nodes, and kidneys. As the infection spreads to the lungs, it causes a cough and fluid between the chest wall and lungs, which leads to chest pains, severe shortness of breath, and potential heart failure. TB also infects bones and joints that can produce arthritis like pain and characteristic bone damage. Another possibility is that it may affect the fluid around the brain, causing meningitis, which can lead to fever, drowsiness, and eventually coma and death (Wingerson, 2009).
Anthrax can be treated in two ways through antibiotics and vaccines. If caught in the early stages antibiotics are useful in killing the B. anthracis as it tries to reproduce in both humans and animals. The second method of treatment is useful only when the individual receives treatment prior to being infected with Anthrax. Before an individual is infected with anthrax they can receive a vaccine that is very useful in combating the bacterium. Vaccines are currently licensed for limited use. People who are considered eligible for the vaccine are members of the military, veterinarians, laboratory workers, livestock handlers, and abattoir (slaughterhouse) workers.
TB is a significant zoonotic disease (a disease of animals which can also infect humans).
The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus.
The condition is more common around tropical locations. There are 856 million people constantly threatened by the disease. It is a discarded issue as it isn’t affecting any developed countries however that does not change the fact that more than 100 million people are disfigured due to this horrid condition. The condition brings irritation to a person and does not allow them to have the freedom of movement. It restricts and limits a person to certain movements. Another symptom of the disorder are repetitive fevers and
T. pallidum is highly sensitive to oxygen and has a decreased ability to survive when not in human body temperature environments 1. The mode of transmission is through sexual contact or vertical transmission from the mother to the fetus. T. pallidum lacks the lipopolysaccharide which is the endotoxin normally present in gram negative bacteria1. The bacterium does produce many lipoproteins which are thought to prompt the inflammatory mediators through the recognition of toll-like receptors1. T. pallidum has a virulence factor of being highly motile due to its ability to propel itself forward by rotating on a longitudinal axis1. The spirochetes easily penetrate the skin or mucosal membranes and spread throughout the lymph nodes and then the blood circulation, affecting many parts in the body1.
for which no cure has yet been created. It is important to know however, that methods are currently available which can prevent the transfer of this virus, and even slow down its malicious effects. before they become fatal. It is equally important to know how to avoid getting the virus and also the symptoms in case you might run across them. They are all a lot.