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who discovered structure of dna
Crick and watson,dna blueprint for life
rosalind franklin discovery of dna essay
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For a long time, scientists have been researching about DNA and its structures. DNA is strongly related to genetics and how living things perform. Two very intelligent scientists, James Watson and Francis Crick, have made history in Biochemistry when they discovered the structure of DNA. The central idea of this paper is researching the history of DNA structure discovery and about why it is very important. Discovery of DNA structure is very important because DNA is what makes all living things behave the way they do and studying DNA also means learning why living things act this way. DNA structure is a key part of organism traits, behavior, and development of all living organisms. For some background information, DNA stands for deoxyribonucleic …show more content…
James Watson and Francis Crick were the two main scientists who discovered the double helix, the main structure of DNA. Two other scientists, named Rosalind Franklin and Maurice Wilkins, also helped and contributed along with James Watson and Francis Crick. However, they weren’t as famous because many people believed that they didn’t play as big of a role in the discovery. These scientists were trying to discover the structure of DNA. Their first discovery was the double helix, and Friedrich Miescher, a swiss chemist, discovered “nuclein” inside nuclei of white blood cells, which its name later changed to nucleic acid and then deoxyribonucleic acid, and abbreviated as DNA. Phoebus Levene, a Russian biochemist, discovered the makeup of nucleotides (phosphate and sugar bases) and all the different parts of both DNA (deoxyribose) and RNA (ribose). James Watson and Francis Crick used this information to determine how all of this DNA was made up and formed. They found that the basic molecule of DNA is called the double helix, and how each of the parts of the double helix were connected (the sugar-phosphate bases acted as the sides of the ladder or the stair rails and the nitrogen bases were the steps) and how they each were arranged. They also discovered about the four nitrogen bases, their shapes, and how you can re-organize them in different orders, but due to their shapes, A and T must be connected to each other and the same goes for G and C. DNA was discovered in the 1800s by various scientists, but James Watson and Francis Crick didn’t determine what the structure of DNA was until 1953. James Watson and Francis Crick met at Cambridge University and met Rosalind Franklin and Maurice Wilkins in London, England. The way that Watson and Crick discovered the structure is that they found that the shape of each nitrogen base and used reasoning to determine that G must fasten
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
The molecule consisted of a double helix with phosphates, deoxyribose sugar molecules, and nitrogenous bases. If the spirals were split, the DNA could replicate, which explained why genes were transferred from parents to their children. Additionally, the order of compounds on the DNA indicated that there was a unique ‘code’ on each strand. Watson and Crick believed that this ‘code’ was translated into specific proteins. , ,
The book Rosalind Franklin and DNA is a biography of Rosalind Franklin written by a British journalist and close friend of hers, Anne Sayre to reveal the true personality of Rosalind Franklin in contradiction to the fallacious character portrayed by James Watson in his personal account of The Double Helix. This book was undertaken to refute Franklin’s distorted portrait from abnormal feminist into rational, perfectionist and talented ‘women’ scientist. She begins by introducing her strong background, curious childhood, dedicated education, generous nature and most importantly how she was brought up in a favorable environment of distinctive Angelo-Jewish family, who identified and cultivated her talents and developed her in a person with full capacity for commitment. In this book, despite admiring the geniuses of Watson in depicting and picking out small information, connecting points and the kind of abilities he possessed was perfectly factitive with Crick that Rosalind and Gosling lacked however, she constantly tries to put the Rosalind’s side of story in picture which she believes was minimized in The Double Helix by Watson and correct her character that distorted in public eye.
DNA is continuously evolving as it has developed various aspects of illicit cases, as well as playing vital roles in all cellular systems. The discovery of DNA has impacted and will trigger the fuel of new findings later in the future. DNA does not only significantly affect a cell’s function, but it aids the species to develop and reproduce, despite the altering conditions.
Chemistry dictates the structure of DNA. DNA is a polymer of monomers called nucleic acids. These are made of a nitrogenous base, a phosphate group and a sugar. It is the negative charge on the phosphate group that makes DNA an acid. There are 4 different bases: adenine, thymine, guanine and cytosine. In groups of three, these four bases can code for any protein coded for in an organism’s genome. Two strands of nucleic acids stack on top of each other in a double helix. The backbone of the nucleic acids consists of the interaction between phosphate groups and the hydroxide groups of nucleic acids. These are held together by covalent bonds called phosphodiester bonds. The helix itself is held together by hydrogen bonds. Although h...
James D. Watson is a molecular biologist, geneticist and zoologist. He is well known as one of the two men who discovered DNA. The other man who helped discover DNA is Francis Crick. Francis is a biologist, neurologist and a biophysicist.
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
She further improved her skills and eventually came to discover through the x-rays that there were two different forms of DNA, the A form and the B form. Franklin chose to focus more on the A form when she presented her findings to an audience, which included James Watson, who was sent by Francis Crick, to spy on her findings. Watson and Crick were rival scientists trying to win the race to find the structure of DNA - before the unknowing Franklin did. When Watson reported back with her information on the A form of DNA, the two were quick to build a model. However, after being invited to the showcase, Franklin came to examine it and nearly immediately disproved the model, showing the reality of the situation - Watson and Crick’s model was a failure. The head of the lab that the two worked at banned them from working on models again, leaving them humiliated. Then, in May of 1952, Franklin took the clearest photo of the B form of DNA she ever had taken and labeled it as “Photo 51”. She stores it away for later examination, but it somehow ends up in the hands of Wilkins, who shows it to Watson. Soon, Watson and Crick, using the photograph and Franklin’s other research, are able to figure out the double helix structure, dimensions, and arrangement of components of DNA. They publish their findings in a series of
She adjusted her equipment to release extremely fine beams of x-rays which extracted finer DNA fibers than ever before where she arranged them into parallel bundles. She studied the fibers in humid conditions which allowed her to discover the many of the crucial findings to DNA structure. Wilkins shared Rosalind's data, without her knowledge, with James Watson and Francis Crick at Cambridge and the two of them soon shot off like a bullet, publishing the proposed structure of DNA in March,
Rosalind was a scientest of the Concept 19 The DNA molecule is shaped like a twisted ladder. James Watson and Francis Crick solved the structure of DNA.
DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. Simply put, DNA contains the instructions needed for an organism to develop, survive and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientist use the term “double helix” to describe DNA’s winding, two-stranded chemical structure. This shape looks much like a twisted ladder and gives the DNA the power to pass along biological instructions with great precision.
The Double Helix tells a tale of fierce competition, perseverance, and scientific innovation as we follow James Watson and his cohort Francis Crick on their quest to discover the secret to life, the structure of deoxyribonucleic acid. Although already fascinated with DNA, Watson struggled with finding chemistry exciting enough to learn it in depth. He had studied birds in college and thereby managed to avoid any formal chemistry or physics courses. As he later pursued a PhD in biochemistry, he realized he could put it off no longer and attempted to learn organic chemistry at Indiana University. However, after a mishap in the lab, he was encouraged instead to study nucleic acid chemistry with Herman Kalckar in Copenhagen. There, his mind strayed from his work and he began doing unauthorized research in the lab of Ole Maaløe, studying phages. Herman stopped teaching Watson after going through a divorce with his wife, and sent Watson off to a scientific conference in Naples. Although he was bored by many of the lectures, Maurice Wilkins’s talk about X-ray diffraction fascinated Watson. He was struck by an X-ray diffraction picture of DNA that Maurice presented and was determined to study the acid. He later got to know more about Maurice’s colleague, Rosalind Franklin, who was proud, stubborn, and very difficult to work with. Watson greatly admired the lecture given by the renowned Linus Pauling, who had discovered the structure of the alpha-helix and was thought of as the leader in DNA research in the scientific world.
What is DNA? DNA is deoxriybonucleic acid which is a molecule that is in a double-helix structure described by James Watson and Francis Crick in 1953. DNA contains our genetic code which is composed of triphosphate molecules, which are also known as the ‘building blocks’ of DNA. There are four bases included in the DNA molecule they are called the four nitrogenous bases. The bases are Thymine, adenine, guanine (purines), thymine and cytosine (pyrimidines) (http://forensicsciencecentral.co.uk/dna.shtml). This shows that DNA isn’t so easy to understand, there is certain bases to make up the DNA molecule. This is important because it helps compose the pieces to DNA and helps find traces to the victim. “The more useful sources include blood, semen, vaginal fluid, nasal secretions and hair with roots” (http://forensicsciencecentral.co.uk/dna.shtml). This quote is important because it singles out the most occurrence of DNA. In order for DNA testing to take place scientists will have t...
In 1953, Dr. Francis Crick and James Watson discovered the structure of the DNA molecule. This is the molecule which we now know stores the genetic information for all life. Many scientists have claimed the discovery to be the single most important development in biology during the 20th century. Watson and Crick's investigation into the nature of the genetic code and the passing of information from generation to generation has redefined the study of genetics. Also, it has basically created the science of molecular biology. For their outstanding work, James Watson and Dr. Francis Crick were awarded the 1962 Nobel Prize.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).