The Cause of The Bubonic Plague

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A germ identified as Yersinia pestis, also known as the plague bacteria, causes the bubonic plague. Yersinia pestis are Gram-negative bacteria found in some parts of the world, mainly Africa, Asia and South America. The bacteria caused around 1000 to 3000 plague cases each year, however only about 10 to 20 of these cases are in the United States.

Yersinia pestis is found most commonly in rats, however it is occasionally found in other animals. Some of the other animals known to carry the bacteria are:

- Mice

- Fleas

- Lice

- Prairie dogs

- Cats

- Dogs

- Squirrels

- Wood rats

- And Chipmunks.

The bubonic plague is usually contracted when an infected flea or rodent bites someone. In some rare cases, the bacteria on a piece of contaminated clothing or other material that has touched an infected person can enter through an opening in the skin. The bubonic plague is rarely spread from person to person.

The bubonic plague can be spread through direct contact with an infected person or animal, or by eating an infected animal.

According to the National Institutes of Health (NIH), the plague can also be spread through scratches or bites of infected domestic cats.

Once the bacteria Yersinia pestis is inside the body it travels to the lymph nodes and begins to multiply. The lymph or lymphatic system is a major part of the body’s immune system. The organs that are in the lymphatic system are the tonsils, adenoids, spleen and thymus.

SYMPTOMS

When a person contracts the bubonic plague infected patients develop a sudden onset of fever, headache, chills, weakness, and one or more swollen, tender and painful lymph nodes (called buboes). These symptoms usually result from the bite of an infected flea. Once it i...

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...teria. Six yops have been identified, however there are probably more. One of the bugs earliest high priority activities is to prevent being destroyed by macrophages and PMNs. Of the six Yops, one is still an enigma- YopM. This Yop is delievered to the cytoplasm just like the others, but it hitches a ride with the cellular trafficking system and ends up entering the cell nucleus. When more research is done on what the YopM does inside the nucleus, it may help identify why the bugs are so vicious.

Works Cited

http://plague.emedtv.com/bubonic-plague/bubonic-plague-causes.html

http://www.healthline.com/health/plague#Causes

http://plague.emedtv.com/bubonic-plague/bubonic-plague-causes-p2.html

http://www.cdc.gov/plague/symptoms/index.html

http://www.healthline.com/health/plague?toptoctest=expand

http://www.research.uky.edu/odyssey/fall02/plague.html

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