Tissue engineering opened a widespread context of studies which performed about three dimensional (3D) cell cultures via imitating the extracellular matrix (ECM) topography to design the scaffolds [1,2,3]. Nanofiber scaffolds have porous structure with large surface area which mimic the natural microenvironment of ECM; the blends regulate the cell nutrition, proliferation, attachment and differentiation [4,5].
Among the material choices to fabricate scaffold, Poly (l-lactide) acid (PLLA) and poly (ε-caprolactone) (PCL) have extensive use due to their numerous advantages of biodegradability, easy access and application, mechanical properties and biocompatibility [6,7]. PLLA, a polyhydroxyacid, is synthesized from Poly L-Lactic Acid that is derived from fermentation of corn, sugar beet or potato. This non-toxic polymer has US Food and Administration (FDA) approve. It is relatively stiff and brittle (semi-crystalline) and its degradation and absorption is in aqueous medium. PLLA has a long term stability of 24 months in vivo [2,8,9,10], same time that injured human tissue needs to cure [11] .The PCL is also an aliphatic, semi-crystalline and non-toxic polyester that its rubbery state could enhance the flexibility of the scaffold. However, PCL is highly hydrophobic which results poor cell attachment in vitro, therefore it needs to modify before cell seeding through plasma treatment, or by coating the scaffold or blending with other materials [2,6,10,12]. Regarding to favorable qualities of PLLA/PCL hybrid such as degradation rate, porosity and resistance to high temperature and pressure, it is well investigated; There are many physicochemical, morphological, thermal and mechanical points of view which pleasantly investigated the PLLA ...
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...out any morphological changes in fiber diameters, shape and size of the pores, or scaffold alignments. ADSCs used as a noble source of cells to seed on hybrids [31,32]. First, we observed the morphological properties of ADSCs on aligned blends. According to the SEM’s pictures when the ADSCs are seeded on scaffolds with parallel patterns; the fibers can conduct the cell’s elongation through themselves. The point is that it happens even after just 1 day of cell seeding (figure1.C, D) indicates the powerful effect of nanofiber orientation as an ECM-like structure on cell growth guidance [35,36]. Comparing ADSCs on gelatin coated (figure1.F) unto uncoated (figure1.E) scaffolds infers that gelatin surface modification did not bend the guidance of cell elongation through fiber’s direction (figure1.E, F); indicating that gelatin coating maintains the scaffold bioactivity.
Cancer occurs when the cells divide and spread uncontrollably in the body creating clusters that have no space to go and eventually create a tumor (a swelling of a part of the body, generally without inflammation, caused by an abnormal growth of tissue, whether benign or malignant) that needs to be removed surgically. Depending on whether the procedure is successful or not, if it is, we can use a remedy for accelerated cell reproduction. Accelerated cell reproduction is the process of increasing
explain to your child why they don’t look like you because of you’re selfishness. Imagine thinking your going to design your baby and turns out it has severe leukemia because scientists didn’t put together your baby right. Where Genetic Engineering and Cloning is headed this is possible. Not only is this effecting your child its affecting the whole world as well. Many people think they only do this in humans it happens in plants and animals too. Genetic Engineering and Cloning changes the natural possess
As a current biomedical engineer student, my interests are drawn towards tissue engineering, as well as orthopedics and oncology. There is a certain degree of emotional attachment to these areas. I was born with one kidney and needed immediate surgery to remove kidney stones last year. I had two bars and twenty-one screws placed in my spine to correct scoliosis at a young age. Finally, my grandmother had colon cancer, which spread like wildfire and killed her within six months. I am naturally drawn
around the world, commitment toward global citizenship, intellectual rigor, and bountiful resources will not only allow me to discover, develop, and deepen my multifaceted interests in engineering but also transform me into a socially aware engineer who is “without borders.” When I was sixteen years old, I met engineering for the first time. Rather than blushing from shyness, I was daunted by the challenge it held: constructing a physical model of the caspase-3 protein based on the atomic coordinate
Robots in Everyday Life Robots are being used to help humans and make life easier. They are used in restaurants, crime fighting, medicine, education, protection, around the home, and even in coffee. There are a few types of robots too, like Industrial robots, social robots, and toys. Robots are able to perform many tasks that humans aren’t able to. This helps to set apart robots from humans and make everyday life a little easier. Robots are being used in restaurants to serve food and drinks, cook
Ever think of what might lay in the future? Imagine being able to look at a screen and pick exactly what your child might look like, anything from it’s physical appearance to it’s athleticism and smarts. Imagine a world where there was the opportunity to have the “perfect” child. A little boy with athleticism like Michael Jordan and smarts like Einstein. A little girl with blonde hair, blue eyes, and a perfect face/body measurements for a model. Impossible? Not anymore. With today’s advances in technology
generations to come. Scientists believe it is the key to finding remedies for hard-to-cure diseases. Cloning is not one, but two differentiated procedures, one being the way of creating wide-ranging medicine and the other creating two identical babies. Taking into consideration how prominent biotechnology has become in recent years, cloning I my crucial analysis of the subject seems to bring the farthest advances and potential. Cloning can be helpful to those who. “The hope is that cells can be generated
Genetic engineering has other possible implications for humans other that solving illness or trying to make a stronger human being. Christians must look at the values that the bible teaches and use them to guild them to what is right. The bible clearly states that you should not kill another so using Eugenics in a race manor and
species. However, genetic engineering has to be appropriately regulated, taking into consideration ethical issues such as human rights, the dignity of the individual, harmful consequences and issues of morality followed by them. This paper will try to expand upon various views on genetic engineering and will pay homage to my background writing engineering research papers to consider the ethics of genetic engineering-the designer baby, cloning, how it relates to ethics in engineering generally, and the responsibilities
during summers between 2011 and 2015. Visiting and talking to patients with diabetes or Graves’ disease left me with admiration and respect for the sensitivity that the doctors showed. These made me see that there was nothing I wanted more than to taking responsibility of the caring for and treatment of patients. The time that the endocrinologist I shadowed spent with the many patients he saw, particularly with the lady who had Graves’ disease, by explaining them the most appropriate treatment procedures
later Biomedical Engineering – Engineering for life. I have seen a glimpse of the kind of future I am aiming for in my existing employment as research assistant assisting medical doctor in breast cancer diagnosis, during my internship in hospital and my time working on final year project for vein graft surveillance programme in hospital. With the body of experiences I have built up during my undergraduate studies and afterward, I see a future career for myself in biomedical engineering. However, my curiosity
where visible above ground growth occurs. Growth occurs through meristematic tissue either through the terminal or apical bud and the vascular cambium. Knowledge of growth areas of the shoot system can aid you in making pruning and shaping choices. When pruning to direct growth or avoid an obstacle it is good to know what will
disorders before you are even born. Genetic Engineering is the scientific process of altering certain genes in living organisms such as plants, animals and humans to achieve a specific beneficial purpose. The pros of genetic engineering include, cures from many if not every incurable disease known today, modifying our food sources so they may grow more in abundance, and nurture an overall healthier generation of children. The cons of genetic engineering include further damaging our environment
animals extreme pain and discomfort. In some cases lab workers do not have the proper training needed to avoid such suffering. Xenotransplantation is another commonly used procedure where cells, tissues, or organs are transplanted from one species to another; this is similar to genetic engineering. Genetic engineering consumes and destroys numerous amounts of animals in attempt to create specific traits in animals. Examples of the animals that are subject to these procedures are cats, dogs, rodents, and
It is no question that an adequate and nutritious diet is required for a high quality of life. With the world’s population on the rise, parts of the world not having access to a proper diet, it is necessary that something be done to further prevent world hunger. There is not enough room on the earth to sustain the growing world. Not only that, there are concerns over the environmental impacts that the meat industry will have on it. Artificial meat is a relatively new technology with the potential