St. John's Wort and Depression

3049 Words7 Pages

St. John's Wort and Depression

What is St. John's Wort?

St. John's Wort scientifically known as Hypericum Perforatum, an herbal remedy generally used to treat depression, is making a rise throughout Europe and the United States. St. John's Wort is a perennial plant that produces abundant yellow flowers and grows naturally throughout much of the world, including specifically in northern California, southern Oregon, and Colorado. It usually flowers on “sunlight hills and forest edges” during the summer, between June and August. It was named after St. John the Baptist and is often harvested and in full bloom around St. John's Day, June 24.

History of St. John's Wort St. John’s Wort has been in use for about 2400 years and has been utilized for many different purposes throughout history. Some of these less modern uses have been nerve tonic, painkiller, including effectiveness for relieving arthritis pain and menstrual cramping, and relief for gastrointestinal problems such as diarrhea, nausea, and more serious problems like ulcers. Now it is becoming more common as a remedy for depression and anxiety but is simultaneously being tested as a possible type of assistance for AIDS patients because it appears to help the immune system combat viruses.

St. John's Wort as an antidepressant

One out of every 20 Americans will become depressed this year. This is obviously a very major and serious problem. St. John’s Wort’s main ingredient, hypericin, is what appears to help alleviate mild to moderate depression, although not much is known about whether or not it proves helpful in severe depression. Hypericin is the red pigment of the plant and it seems to inhibit monoamine oxidase (MAO) and the breakdown of the brain’s neurotransmitters and is also a SRI, serotonin reuptake inhibitor. However, according to Jean Carper in Miracle Cures, “recent research finds hypericin less potent an antidepressant than the whole plant extract itself, suggesting the herb’s complex mixture of chemicals, including xanthones and flavonoids, also are critical in the plant’s pharmacological benefits”.

St. John’s Wort is becoming increasingly popular mostly due to the lack of side effects. Other prescription antidepressants such as Prozac, Zoloft, and Paxil often produce effects like weight loss, sexual dysfunction, and insomnia. In a controlled study of St. John’s Wort, only 2.

Open Document