Sepsis: Early Detection and Implementation of Sepsis Resuscitation Bundle

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Sepsis: Early Detection and Implementation of Sepsis Resuscitation Bundle

Sepsis is defined as the body’s inflammatory response to an infection and can quickly lead to multiple organ failure and death. Early, goal-directed therapy using the sepsis resuscitation bundle introduced in the “Surviving Sepsis Campaign” is the treatment used throughout the world for sepsis treatment (Winterbottom 2012, pp 247). There are approximately one million cases of sepsis in the United States annually and deaths total more than prostate cancer, breast cancer, and HIV/AIDS combined. Also, more than one-fourth of patients that develop sepsis will develop it on a medical-surgical unit and severe sepsis is the most common cause of death among patients in non-coronary critical units (Bernstein 2013, pp 24-25).
Education of all nurses, not just critical care nurses, of the early signs and symptoms of sepsis and quickly implementing the sepsis resuscitation bundle is crucial to decreasing the mortality rate of sepsis.
Literature Review
“Early Recognition and Treatment of Sepsis in the Medical-Surgical Setting,” focuses on the nurse’s role in being able to identify early signs of sepsis and initiating the sepsis bundle quickly. In the article, “Nurses’ Critical Role in Identifying Sepsis and Implementing Early Goal-Directed Therapy,” it explains how the interventions in the sepsis bundle have decreased mortality from 37% to 30.8% in a two year study conducted in 165 different health care sites. This article also details clinical guidelines and timelines for implementing the sepsis bundle. Early stages of sepsis and clinical manifestations are discussed in the article, “Helping Patients Survive Sepsis,” with emphasis on the i...

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...urses are at the bedside 24 hours a day they can greatly impact patient outcomes and decrease the overall mortality rate of sepsis by using the evidence-based practices outlined in the Surviving Sepsis Campaign.

Reference Page
Bernstein, M., & Lynn, S. (2013). Helping patients survive sepsis. American Nurse Today, 8(1), 24-28. Retrieved from
Gobel, B., & Peterson, G. J. (2010). Sepsis and septic shock. Clinical Journal Of Oncology Nursing, 14(6), 793-797. doi:10.1188/10.CJON.793-797.
Tazbir, J. (2012). Early recognition and treatment of sepsis in the medical-surgical setting. MEDSURG Nursing, 21(4), 205-209.
Winterbottom, F. (2012). Nurses’ critical role in identifying sepsis and implementing early goal- directed therapy. The Journal of Continuing Education in Nursing, 43(6), 247-248. Doi:10:3928/00220124-20120523-33.

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