Rabies Research Paper

Rabies a viral disease to warm blooded animals, its timeline dates back as far to 2300 BC. Research shows that dog owners of Babylonian city of Eshnunna (modern Tell Asmar in Diyala Province, Iraq) were fined for their dogs biting and causing death to people of the city. Rabies causes panic and fear into people in 1759-1762 making it a grim barbaric scene in London where street dogs were shot and given a reward restricting dogs to a month of confinement. In the 1800 hundreds becoming a widespread problem to the Western, Northern and Eastern part of Europe, Presenting itself back in North America and Canada to England to never go away. A mass of foxes become infected in France in 1803 this to date has been the largest outbreak to be seen killing

The virus is classified in the Rhabdoviridae family, a bullet shape virus. That consists of five proteins nucleoprotein (N), Phosphoprotein (P), Matrix protein (M), Glycoprotein (G) and Polymerase protein (L). Rhabdoviruses have two major structures the helical ribnucleoprotein core (RNP) and a surrounding envelope. Shortly after a human or animal is bitten the virus will move along up to the nerves and multiply inside the brain, once inside the brain it will travel back down into the rest of the bodies nerves. Once inside the brain the virus has multiplied and the animal will show signs of

In dogs a funny sound to their bark or a droopy tongue will appear, prodromal is the stage of behavior uncommon traits in animals such as wild animals being friendly the second stage is the excited, furious stage where an animal will appear hyperactive and attack any inanimate object. Lastly the paralytic stage the animal has lost mobility in the hind limbs eventually causing death. In human’s hydrophobia a (fear of water) the furious stage is seen in the later stages of the disease, the human has difficulty swallowing shows signs of panic, and cannot quench thirst. Since saliva is the route of transmission when presented with liquids into the infected human it causes muscle and painful spasms. Symptoms can be paralytic, anxiety, insomnia, confusion and abnormal behavior the first signs in a human are flu like