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There is little information about the pathology of autism, owing to the small number of brains examined. Failure to acquire language at the expected age is the most frequent presenting complaint for preschool autistic children. In fact, all preschool autistic children have some type of development language disorder (dysphasia) (Mesibov and Shea 1996). In contrast to non-autistic dysphasic children, some of whom have predominantly or purely expressive disorders, virtually all pre-school autistic dysphasic children have impaired comprehension of language. Some autistic children are mute and seem to understand very little of what is said to them.
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