Portable Capilary Electrophoresis Insturment

Better Essays
Portable instrumentations for field analysis is growing rapidly due to its availability of results, elimination of complications with sample storage and transport, and better cost effectiveness than conventional benchtop analytical systems. Portable analytical instruments need to have compact size, lightweight, robustness, and low power consumption along with automation of operation.1 Capillary electrophoresis (CE) is the separation of a mixture into its components by a strong electric field imposed between the two ends of a narrow capillary tube filled with electrolyte solution, which separated solutions by differences in mobility without the presence of stationary phase.2 With advantageous properties including a wide range of accessible analytes, high separation efficiency, short analysis time, low power requirements, limited consumption of chemicals, and ease of installation, operation, and maintenance, CE is a potential candidate for portable analytical instrumentation.
Analysis using CE are mainly performed using optical detection, utilizing either absorbance or (laser-induced) fluorescence. However optical detection methods can only be applied with high power light source and is not ideal for non-light-absorbing inorganic or organic ions.3 Recently, electrochemical detection methods are suggested as a better option for portable CE, as their completed electronic configuration can easily be miniaturized and translated into the compact, low power format.4 Out of many electrochemical detection methods, capacitively coupled contactless conductivity detection (C4D), a particular type of conductivity-based detector where the electrodes are not in direct contact with the measured solution, is the most suitable option for CE portable...

... middle of paper ...

...eter C. Hauser. "Contactless conductivity detection for electrophoretic microseparation techniques." The Chemical Record 12.1 (2012): 106-113.
5. Brito‐Neto, José Geraldo Alves, et al. "Understanding capacitively coupled contactless conductivity detection in capillary and microchip electrophoresis. Part 1. Fundamentals." Electroanalysis 17.13 (2005): 1198-1206.
6. Kubáň, P., Nguyen, H., Macka, M., Haddad, Paul R. and Hauser, Peter C. (2007), New Fully Portable Instrument for the Versatile Determination of Cations and Anions by Capillary Electrophoresis with Contactless Conductivity Detection. Electroanalysis, 19: 2059–2065. doi: 10.1002/elan.200703908
7. Kubáň, Petr, et al. "In situ determination of nerve agents in various matrices by portable capillary electropherograph with contactless conductivity detection." Journal of Chromatography A 1218.18 (2011): 2618-2625.
Get Access