Pharmacologic Therapies for the Treatment of Rheumatoid Arthritis

923 Words2 Pages

Rheumatoid Arthritis or RA is an autoimmune disease with an unknown etiology that affects one percent of the world's population. RA causes chronic inflammation and joint pain. Findings from physical examinations are the main way of clinically diagnosing RA. To this point, the exact cause of RA is still unknown. The signs of "swelling, bony erosions, and synovial thickening" (Gibofsky) show the hidden signs of inflammatory and autoimmune process. More complex signs of RA lead to synovial hyperplasia, bony erosion, and cartilage damage which generally affect 80% of people with RA within the first year of diagnosis. Once there is eroded bones, there is is no sign of repairing the bone. This gives the suggestion that the prevention of bone erosion is a goal. RA also causes joint damage which may lead to pain and disability. The severity of the pain and physical disfunction show the degree of the disease. RA is affected by the severity of the disease and the effectiveness of treatment. Remission occurs in 20% or less of people. Standard disease activity indices are used to determine the best treat to target approach using pharmacologic intervention. The front line treatment for Rheumatoid Arthritis is with the use of medication. The three main pharmacologic therapies for treating Rheumatoid Arthritis are nonsteroidal inflammatory drugs (NSAIDs), glucocorticoids, and disease-modifying antirheumatic drugs (DMARDs). Out if the three pharmacologic therapies listed above, nonsteroidal inflammatory drugs or NSAIDs are the most commonly used medication for controlling stiffness, pain and inflammation from rheumatoid arthritis. For the first few weeks NSAIDs can be very useful while undergoing diagnosis and a tr... ... middle of paper ... ...sability and mortality. It is important for people who see these symptoms to get diagnosed and begin treatment before any extensive joint and bone damage occurs. This will bring hope in further improvements in the management if rheumatoid arthritis. Works Cited Curtis, Jeffrey R., Angelo Gaffo, and Kenneth G. Saag. “Treatment of rheumatoid arthritis.” American Journal of Health-System Pharmacy 63.24 (2006): 2451+. Academic OneFile. Web. 25 Jan.2014 Gibsofsky, Allan. “Overview Of Epidemiolgy, Pathophysiology, and Diagnosis Of Rheumatoid Arthritis.” American Journal Of Managed Care 18. (2012): S295-302. CINAHL Plus with Full Text. Web. 25 Jan. 2014 Schneider, Matthias and Klaus Kruger. “Rheumatoid Arthritis—Early Diagnosis and Disease Management.” Deutsches Aerzteblatt International 110.27/28 (2013): 477-484. CINAHL Plus with Full Text. Web. 25 Jan. 2014

More about Pharmacologic Therapies for the Treatment of Rheumatoid Arthritis

Open Document