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Essays on penicillin
Discovery of penicillin essay
Was science the main factor in the development of penicillin
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Inventions are not always begot from necessity; sometimes it is the twist of a thread on the loom of fate that produces the most amazing discoveries. The invention of penicillin-arguably one of the greatest medical discoveries of all time-was discovered completely by happenstance. Penicillin started as an accident, then was believed to contain medical potential, and experimented with to create the antibiotic widely used today.
First of all, penicillin was discovered by chance by bacteriologist Alexander Fleming. Mr. Fleming, who wasn’t known for keeping a neat or orderly lab, left for a month long vacation. According to, “Not-So-Dumb Luck” by Jessie Lane, when he came back, every dish he had left out in the open was covered in mold and looked them all over. On the contrary, he did not instantaneously notice the effect of the mold, Penicillium notatum. While showing the randomly picked culture to his former lab member, is when the mold perked his interest. It seemed, as it had grown, it killed the bacteria in the culture. Mr. Fleming wrote a paper on his findings but wasn’t able to determine how to use the penicillin in humans.
That is where Howard Florey and Ernst Chain come in.
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They believed there was medical potential in it. Chain and Florey’s research took place during World War II, in 1939 and 1940. According to, “The Discovery of Penicillin” by Brittany Connors, their effort was increased in discovering how penicillin could be used on humans because of the need for a drug to reduce bacterial infections in soldiers’ wounds. After they were able to demonstrate penicillin’s ability to kill infectious bacteria, they turned to the United States for help to be able to produce the quantities of penicillin needed for clinical human
The Factor of War in the Development of Penicillin The discovery, development and subsequent use of penicillin can be considered to be one of the most important breakthroughs in medical history. There were many factors, which were involved in the development of penicillin, and it could be argued that war was the most important, but other factors were also responsible. Alexander Fleming was working in London as a bacteriologist in 1928 when he noticed that a growth of a mould called penicillin produced a substance that actually killed the germs he was working on. He realised that this might be very important and a year later he wrote an article about his findings. However, Fleming did not have the facilities or the support to develop and test his idea that penicillin could fight infection, and he didn't develop it further.
Medicine has been developed and discovered for thousands of years; however, the 1920’s was the first decade that fashioned a pathway for new developments and discoveries. Medical professionals have taken a huge hit for their fight in finding new inventions that can save patients from death’s hands. In the 1920’s, medicine has also taken a tremendous leap in controlling fatal diseases such as diabetes (Pendergast 110). Medicine in the 1920’s has altered the way medicine is shaped today; furthermore, the development and discovery of the iron lung, penicillin, and insulin were the first pertinent breakthroughs in medical history (“Iron” par. 7; Grimsley par. 15; “Banting” par. 13).
Adegoke AA, Tom M, Okoh AI, Jacob S (2010) Studies on multiple antibiotic resistant bacterial isolated from surgical site infection. Scient Res. Essays 5:3876-81.
The unknown is commonly something that people fear, but what happens when intelligent individuals dare to uncover the facts within it? The answer to this question is that remarkable discoveries are made that change human knowledge, technology, and health forever. Possibly the most beneficial of these discoveries are the ones involving the betterment of human health. Doctors and scientists are often viewed as the most intellectual people in the world’s communities, but they are still human and therefore prone to error. However, Morton A. Meyers’s book Happy Accidents: Serendipity in Modern Medical Breakthroughs explores the various positive outcomes that arose from human error. Specifically, Meyers writes about the diverse serendipitous breakthroughs
Most of these medical advances were a result and were an influence of World War I. Probably one of the most important medical advances was the discovery of penicillin in 1928 by a Scottish, microbiologist named Alexander Fleming, he had actually accidently discovered it, when he noticed that a bacteria culture he had been growing, had stopped, he realized that it had been contaminated by a rare form of mold called Penicillin and that it had killed the bacteria.
Throughout history, we have come to significant inventions and discoveries that have influenced our lives greatly. It is obvious that these inventions and discoveries occasionally occur at the cost of making major mistakes, but are they always worth it? Errors can either lead to difficulties, and can also lead to development. So the real question is, “Are mistakes a key part of making discoveries and inventions?” Well, after gathering the facts, I think that mistakes are in fact a key part of discovering. There are many reasons as to why errors contribute to helping making inventions and discoveries, but I only have three. First of all, mistakes are an important part to making inventions because they help you determine what you did incorrect
Penicillin is the reason people lived healthy and long lives. Sick, cold, and sore, are feelings people have when they are sick. If people were to become sick and penicillin was not around they would have those feelings for a longer duration. Penicillin was an idea that belonged to a famous scientist by the name of Sir Alexander Fleming. Penicillin was just the slightest of idea in Fleming’s mind after he married his wife who had the profession of a nurse. Fleming made penicillin after conducting test on accidentally infected fungus inhabited plates. He tried washing the fungus of with disinfectant, then he noticed a yellow-green zone around the fungus. He came up with the conclusion that penicillin’s main goal would be to eliminate the outer weak ring
Ernest Chain and Howard Florey with the knowledge of Flemings work were able to successfully purify an extract of penicillin for testing. The tested it in 1940 on mice, they concluded that those who were given the penicillin lived whereas the others did not. Later in 1945 all three men received the Nobel Prize for their contr...
Penicillin, derived from the mold Penicillium, is the first antibiotic to successfully treat bacterial infections on humans. It was accidentally discovered by scientist, Alexander Fleming. While Fleming was growing Staphylococcus, a serious and often deadly infection, in a dish, he noticed the bacteria had stopped growing after a mold found its way
A remarkable breakthrough in medicine occurred in the late 1800s through the work of Louis Pasteur. Pasteur's experiments showed that bacteria reproduce like other living things and travel from place to place. Using the results of his findings, he developed pasteurization, which is the process of heating liquids to kill bacteria and prevent fermentation. He also produced an anthrax vaccine as well as a way to weaken the rabies virus. After studying Pasteur's work, Joseph Lister developed antisepsis, which is the process of killing disease-causing germs. In 1865 before an operation, he cleansed a leg wound first with carbolic acid, and performed the surgery with sterilized (by heat) instruments. The wound healed, and the patient survived. Prior to surgery, the patient would've needed an amputation. However, by incorporating these antiseptic procedures in all of his surgeries, he decreased postoperative deaths. The use of antiseptics eventually helped reduce bacterial infection not only in surgery but also in childbirth and in the treatment of battle wounds. Another man that made discoveries that reinforced those of Pasteur's was Robert Koch. Robert Koch isolated the germ that causes tuberculosis, identified the germ responsible for Asiatic cholera, and developed sanitary measures to prevent disease. (1)
Discovery and Development of Penicillin. (2014, April 4). Retrieved from American Chemical Society International Historic Chemical Landmarks: https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html
Thesis: With the advent of antibiotics in 1929 Fleming said, "The time may come when penicillin can be bought by anyone in the shops.Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant."With the overuse of antibiotics today we have seen this very idea come to be.Over usage is caused most prevalently by a lack of education on the part of the patient.Thus stated, the way to overcome such a circumstance is to educate, not only the patient but also the physician.
The discovery of antibiotics is attributed to Alexander Fleming who discovered the first antibiotic to be commercially used (Penicillin) in approximately 1928. An antibiotic, also known as an antimicrobial, is a medication that is taken in order to either destroy or slow the growth rate of bacteria. Antibiotics are integral to the success of many medical practises, such as; surgical procedures, organ transplants, the treatment of cancer and the treatment of the critically ill. (Ramanan Laxminarayan, 2013)
The most important and influential discovery was the practice of surgery. With this invention, human life became more sophisticated, humans lived longer, and we obtained a knowledge of ourselves sufficient enough to break the boundaries built by ignorance. Lacking prescription drugs, accurate tools, computer technology, and any background experience to build from, our ancestors struggled to learn how to repair the human body. They did an suprisingly competent job of treating the sick and injured. Some of the medical technology developed in ancient times surpassed anything available in the modern world until the 18th century or 19th century. In eras wherein religious views took precedence over medicine and logic, surgical advancement was difficult. The knowledge we have now was obtained from these people's exploits.
Medicine is one area that constantly looks to use prior knowledge to discover new things. Take the HeLa cells for instance. The initial discover of these cells occurred in 1951. These cells came from a black woman named Henrietta Lacks. She was diagnosed with cervical cancer. He doctor took a segment of her tumor and sent it to Dr. George Otto Grey, who was the first scientist to successfully grow human cells in a culture. These cells would go on to be used in research for cloning, the polio vaccine, gene mapping and in virto fertilization. These cells were important to science because no scientist had an endless supply of cells ...