She had a patient in which memory loss and other brain issues deteriorated rapidly resulting in death a short period later (Castellani, Rolston, & Smith, 2010). Alzheimer’s dementia affects individuals older than the age of 65. This disease occurs in a small percentage of individuals younger than 65. Literature varies in the percentage. According to Jorde, Carey, and Bamshad (2014), 3% to 5% of individuals diagnosed before age 65 are most likely to have inherited to dominant gene(s) for Alzheimer’s Dementia.
Genome-wide Analysis of Genetic Loci Associated with Alzheimer Disease. Retrieved December 1, 2013, from The Journal of the American Medical Association: http://jama.jamanetwork.com/article.aspx?articleid=185849
Without a new cure it is estimated that alzheimers will affect over 14 million people by 2050. The elderly are the most infected with the disease and its still spreading. Other disease in common with Alzheimer’s is multi-infract dementia, Huntington’s disease, Pick’s disease, and Parkinson disease. People wonder if Alzheimer is genetic “meaning runs in families” the answer is the evidence isn't clear. Doctors and Physicians say if you have a by blood family member with Alzheimer's there's a slightly greater chance of getting or having the Alzheimer's disease.
Her symptoms were comprised of memory loss, language problems, and unpredictable behavior. After her death, Dr. Alzheimer examined her brain and found many abnormal clumps (amyloid plaques) and tangled bundles of fibers (neurofibrillary tangles). The aforementioned plaques and tangles in the brain are considered two of the primary features of Alzheimer’s disease. The third feature is the loss of connections between nerve cells or neurons in the brain. There is currently no cure for this traumatic disease, but current Alzheimer’s disease medications and management strategies may temporarily improve symptoms.
Furthermore, there is sometimes a very dominant pattern of inheritance of this disease, where a person has a fifty percent chance of acquiring it if either parent has Alzheimer’s (autosomal dominant transmission) (1,2). It is rare to acquire Alzhei... ... middle of paper ... ...al and family study of 22 twin pairs. Neurology, 1987, 37, 359-3B3. 4. Thomas, C. L. Alzheimer’s Disease.
(r.1) Statistics exemplify the discovery of one specific gene which contributes to the increasing rate of late-onset Alzheimer’s. Person’s with rare, familial types of Alzheimer’s are found connected to hundreds of families linked to a specific gene. (r.1) Those whom inherit the specific gene are almost guaranteed to obtain the Alzheimer’s disease. The gene also will affect the person by the age of sixty-five, and even as early as their thirties and forties. (r.1) Another popular theory for the cause of the disease other then genetics includes the decreasing of brains cells through either strokes or ageing.
Within these bunches of nerve cells were also what is now known as plaques. Later, in a medical journal, Dr. Alzheimer, discussed his hypothesis of the bundles and plaques being the cause for the patient’s memory loss (Tagarelli, 2006). Background It was once the norm to associate a decline in one’s memory to be a part of typical aging. As it has been proven, a marked decline in cognition is an unexpected outcome of the aging process. A decline has actually been identified to be cause for concern and thus falls under the broad scope of dementia.
Analysis of Dementia Overview The term dementia refers to a serious loss in memory and other intellectual abilities in a formerly unimpaired person, further than what might be expected from normal aging (Dhanani & Wilkins, 2008). The origin of the word dementia is from a latin word “demens” meaning insane or being out of one’s mind (Banerjee, 2011, p.2). According to Miller (2009, p. 263), dementia is a syndrome not a disease, that means it is a pattern of symptoms that can be caused by many different illnesses. There are approximately twenty four million people with dementia in the world, with an additional four and a half million newly identified every year (Ferri, Prince, Brayne, Brodaty, Fratiglioni, 2005, p. 2113). Types of Dementia The most common types of dementia are the primary dementias; which occur as a result of pathological conditions of the brain.
Lu, Der Fa,PhD., R.N., & Herr, Keela, PhD, RN,A.G.S.F., F.A.A.N. (2012). Pain in dementia: Recognition and treatment. Journal of Gerontological Nursing, 38(2), 8-13. doi:http://dx.doi.org/10.3928/00989134-20120113-01 National Institutes of Health (December 2012). What is Alzheimer’s disease?
Alzheimer’s disease if the most common type of dementia, and contributes to 60-70 percent of dementia cases (WHO). Patients with Alzheimer’s disease often show problems with memory, judgment, and thinking. “One in ten people over 65 years of age, and over half of those over 85 have Alzheimer’s disease. Currently, 26 million people worldwide have this dementia, and over 15 million Americans will be affected by the year 2050” (HelpGuide). There are other types of dementia; one is dementia with Lewy bodies, which is very similar to Alzheimer’s disease.