Parkinson's Disease and Effective Medication

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History of Parkinson's Disease
Parkinson's has been around since the beginning of time. However, it has not always been know as Parkinson's disease. A London doctor by the name of James Parkinson first brought attention to the subject by publishing a medical essay. The publication titled "An Essay on the Shaking Palsy" help established Parkinson's disease as an accepted medical condition. Dr. Parkinson intended the publication to spark interest in others in hopes they may do further research on the disease. However, it took around 60 years after it was published before someone took interest in study of the disease. Jean Martin Charcot was next to bring awareness to the disease. He remarked at its importance and coined the name Parkinson's disease.
In the 1960's, research led scientists to discover that Parkinson's patients' brains are chemically different. It showed patients with Parkinson's having low levels of dopamine caused by the degeneration of nerve cells in the part of the brain called the substantia nigra, which is considered the midbrain where motor function is located. This discovery led to the first effective medication in the treatment of the symptoms related to the disease and is still used to this day.
Since the 1960's research continued in hopes to unearth more knowledge about the disease. There is much that has been learned about this disease, though there is a great deal more we need to know to develop a cure. The symptoms are progressive and degenerative and tend to be more common in older individuals. It is understood that a dopamine deficiency in the brain is the source, yet why this initially occurs is unclear. Although there is no cure for the disease, its symptoms can be managed with medic...

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...s reason may be told to maintain a low-protein diet, and wait 30 minutes to an hour after taking medication to eat (Levodopa and Carbidopa, 2014).

Works Cited

Goetz, C. G. (2011). The History of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies. Cold Springs Harbor Perspectives in Medicine. Doi:10.11.1/cshperspect.a008862
Levodopa and Carbidopa. (2014). AHFS Consumer Medication Information, 1.
Neurologic Disorders. (2013). MPR - Pharmacist's Edition, 7(4), 154-170.
Poulopoulos, M., & Waters, C. (2010). Carbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson's disease. Core Evidence, 5(1), 1-10.
Sun Pharmaceutical Industries Limited. (2014). Carbidopa and Leveodopa Tablet, Extended Release. Retrieved from Daily Med: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d2a64f14-f638-49d9-8a96-cb7ae46ac3ea
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