Parkinson's Disease

Parkinson's Disease

Damage to Broca's area in the frontal lobe causes difficulty in speaking and writing, a problem known as Broca's aphasia. Injury to Wernicke's area in the left temporal lobe results in an inability to comprehend spoken language, called Wernicke's aphasia. Cerebral palsy is a broad term for brain damage sustained close to birth that permanently affects motor function. The damage may take place either in the developing fetus, during birth, or just after birth and is the result of the faulty development or breaking down of motor pathways. Cerebral palsy is non-progressive that is, it does not worsen with time. During childhood development, the brain is particularly susceptible to damage because of the rapid growth and reorganization of nerve connections. Problems that originate in the immature brain can appear as epilepsy or other brain-function problems in adulthood.

Parkinson's Disease, progressively disabling neurological disease marked by tremor and increasing stiffness of the muscles. The onset of this disease is gradual, which makes it difficult to diagnose in its early stages. Tremor usually begins in one or both hands; eventually the thumb and forefinger may show a rapid repetitive movement described as "pill rolling." In addition to muscular rigidity, other symptoms include slow body movement, poor coordination, and faulty balance. A shortening of muscles along the front of the neck tends to bend the head and spine forward, while the lack of animation in the face creates a mask like expression. As these symptoms worsen, chronic fatigue, mental confusion, and speech impairment may develop and the person with Parkinson's may find it impossible to walk unassisted.

The symptoms of Parkinson's diseas...

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... in the treatment of Parkinson's disease. These drugs appear to have fewer side effects than some of the older medicines. Other drugs that affect the action of central nervous system neurotransmitters have proven useful in relieving tremors.

Brain surgery, a common method for treating Parkinson's before the discovery of L-dopa, is coming back into favor for patients with severe tremors. Surgeons use various procedures to destroy tissue in regions of the brain believed to play a role in Parkinson's disease, such as the substantia nigra. These procedures have positive effects for some people, but experts caution that they do not work for everyone. Additional surgical treatments are under investigation. Such experimental treatments include a pacemaker-like device to prevent tremors, and more recently, replacing damaged neural tissue with healthy fetal neural tissue.