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Repair and restoration theory of sleep
Repair and restoration theory of sleep
The comparative investigation of sleep has led to an important conclusion
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One of the most persistent topics that often holds humanity’s interest is the actuality and purpose behind their own biological functions. Many hold a desire to grasp and understand the concepts of how their body and brain works, and the evolutionary purposes behind every facet of the human existence. Among the most explored functions exists the process of sleep, one of the most mysterious quirks that have puzzled evolutionary biologists for generations. While many understand some basic science associated with sleep, the average person knows so little about the neurological and physiological science and purpose behind it. Many levels of comprehension and theory exist past the layman’s understanding of what sleep is and why it exists. Even though …show more content…
In their article “The cognitive neuroscience of sleep: neuronal systems, consciousness and learning,” Allan J Hobson and Edward F Pace-Schott attempt to further study brain functions during sleep and unearth their implications. Studies have shown how that the electrical patterns of rest are generated from subcortical and cortical regions within the brain (Hobson and Pace-Schott 680). These generations are not only found in human brain functions, but across many different species of animals. From the transition of waking to NREM sleep, almost all neurons show a decrease in firing, most likely resulting from the different activities that occur in the brain in the front regions of the brain, coming from the brainstem (Hobson and Pace-Schott 680). These activities are possibly influenced by the hypothalamus and circadian rhythms, meaning that waking neurological functions can have an influence and interference on the patterns that occur during sleep (Hobson and Pace-Schott 680). Neurons fire at a similar rate of waking activating during NREM sleep. The thalamus’s influence over the brain activities show themselves to be one of the biggest influences over sleep’s change in consciousness from waking activity, demonstrating how waking functions and separate areas of the brain hold a strong connection to functions occurring during sleep (Hobson and Pace-Schott …show more content…
Their dispelling of the myth that dreaming is exclusive to REM sleep paints a picture of a more complex dreaming phase, suggesting that it is not as linearly and stagnantly linked to consciousness as one may think. This further shows a fuller picture of sleep being a dynamic process that many continue to still study and understand. The better one understands how sleep occurs and the different patterns that are seen during rest, the easier one can ponder why animals sleep in the first place and why it is
Sleep deprivation is a commonplace occurrence in modern culture. Every day there seems to be twice as much work and half as much time to complete it in. This results in either extended periods of wakefulness or a decrease in sleep over an extended period of time. While some people may like to believe that they can train their bodies to not require as much sleep as they once did this belief is false (1). Sleep is needed to regenerate certain parts of the body, especially the brain, so that it may continue to function optimally. After periods of extended wakefulness or reduced sleep neurons may begin to malfunction, visibly effecting a person's behavior. Some organs, such as muscles, are able to regenerate even when a person is not sleeping so long as they are resting. This could involve lying awake but relaxed within a quite environment. Even though cognitive functions might not seem necessary in this scenario the brain, especially the cerebral cortex, is not able to rest but rather remains semi-alert in a state of "quiet readiness" (2). Certain stages of sleep are needed for the regeneration of neurons within the cerebral cortex while other stages of sleep seem to be used for forming new memories and generating new synaptic connections. The effects of sleep deprivation on behavior have been tested with relation to the presence of activity in different sections of the cerebral cortex.
Another reason for the difficulty of sleep research is the pace of discovery. The field moves too fast for its own good. As a result, no comprehensive beginner’s text is available in the field of circadian rhythms. By the time...
As we all know, sleep is an important part of our lives. Without the proper amounts and type of sleep, fatigue and other problems can arise. Generally, we can clearly distinguish between a sleeping person and a person that is awake. With sleeping disorders, the distinction between an awake person and a sleeping person becomes more intriguing. What is the difference, how does it relate to the I-function and consciousness? Each sleeping disorder has its own unique answer to this question. It is essential to understand sleep to fully appreciate it. However, many aspects of it remain a mystery. We do have some degree of understanding of sleep. Within our sleep cycle a type of unusual sleep occurs, REM sleep. During this cycle the periods of REM sleep are interspersed with slow wave sleep in alternation. Each period of REM sleep (there are usually 4 or 5 periods a night) lasts for approximately 5 to 30 minutes. During these periods a sleep paradox occurs. An enormous amount of brain activity takes place; this is sometimes even more activity then when awake. This clearly indicates that sleep is not simply to rest our mind and not to think. So, during this period our brains are extremely active, yet there is usually no input or output. During this period, along with the random eye movement (REM), there is a complete loss of muscle tone. Essentially, at this point, the motor system is paralyzed (normally the body inhibits any movement). The autonomic nervous system also alters its behavior. The regulation of body temperature is lost and the blood pressure, heart rate, respiratory rates shows increased variability. REM sleep can be detected by measuring the electrical activity of the brain with an electroencephalogram. At this point, the EEG will show the same pattern of activity as when the brain is awake.
We live our entire life in two states, sleep and awake1. These two states are characterized by two distinct behaviors. For instance, the brain demonstrates a well-defined activity during non-REM sleep (nREM) that is different when we are awake. In the study of sleep by Huber et. al., the authors stated that sleep is in fact a global state2. It is unclear whether this statement means that sleep is a state of global behavioural inactivity or the state of the global nervous system. The notion that sleep is a global state of the nervous system served as basis for sleep researchers to search for a sleep switch. The discovery of the sleep switch, in return, provided evidence and enhanced the notion that sleep is a global state of the nervous system. The switch hypothesis developed from the fact that sleep can be initiated without fatigue and it is reversible1. It was hypothesized that there is something in the brain that has the ability to control the whole brain and initiate sleep. Studies have found a good candidate that demonstrated this ability3. They found a group of neurons in the Ventrolateral Preoptic (VLPO) nucleus. It was a good candidate because it was active during sleep, has neuronal output that can influence the wakefulness pathway, and lesion in the area followed reduce sleep3. The idea that there is something that can control the whole brain and result sleep state supports the idea that sleep is a global state of the nervous system.
An investigation of the control, and perhaps the origin, of sleep might best begin with the hypothalamus, a flat, horizontal structure in the brain that is known to play an important role. Damage to the back portion of the hypothalamus causes somnolence, indicating that when intact, it sustains alertness (1). In contrast, damage to the front part indu...
studying the subject, the origins in the brain responsible for sleep are still not fully understood and thus, facilitate continual probes
Sleep is defined as a reversible, natural state of reduced responsiveness to external stimuli and relative inactivity, accompanied by a loss of consciousness1. This state of inactivity has been evolutionary conserved across species against many selection pressures. This suggests that sleep holds a vital function. Multiple studies have suggested that sleep enhances both declarative and procedural memory 2,3. Consequently, memory consolidation is one of the ostensible functions of sleep. The active system consolidation hypothesis and the synaptic homeostasis hypothesis (SHY) are the two main hypotheses for this putative function of sleep. The active system consolidation model proposes that the repeated reactivation of newly encoded representations in the hippocampus during slow wave sleep (SWS) drives a transfer of memory traces from short-term store in the hippocampus to neocortical regions for long term storage4. These representations are stabilized in the neocortex during subsequent periods of REM sleep by synaptic potentiation5. SHY proposes that sleep acts to homeostatically renormalize synaptic weight to counteract the potentiation that occurs during wake6,7. This occurs by an activity dependent downscaling of synaptic weight during SWS. These models are often portrayed in direct opposition, largely due to the active potentiation proposed in the active system consolidation model, in contrast to the global downscaling (depotentiation) of SHY. However it has recently been considered that these two models may not be mutually exclusive, but could act in unison8. This essay will analyse what I believe to be the best evidence in support and against each model to contend the role of sleep in memory consolidation. The rol...
A most popular theory on why we sleep is the restorative theory of sleep:
Sleep is important to the brain, because it is believed that when we sleep it restores brain chemicals and provides rest to the body.
A restorative theory claims that sleep is used to repair the body including the brain. Oswald suggests that slow wave sleep is when body repair occurs and REM sleep is when the brain is repaired. This is supported by the fact that there is an increase in the secretion of growth hormones during SWS. This could also explain why brain activity levels are high during REM sleep, and similar to when awake.
Sleep is a necessary, regularly repeating occurrence of rest defined by decreased motion, decreased consciousness, and distinguishing stages of activity in the brain. (189)
Kales, A. (1972). The evaluation and treatment of sleep disorders : Pharmacological and psychological studies. In M. Chase (ed.)The Sleeping Brain. Los Angeles : Brain Information Service.
The article, "New Neurons in the Adult Brain: The Role of Sleep and Consequences of Sleep Loss," published in Sleep Medicine Reviews (I)
The human body is a complex system of intricate veins, muscles, and organs that require food, water, and sleep. Humans take both food and water from outside sources but people cannot take sleep from any exterior sources. The human populous of today is largely affected by insomnia. Many people who are affected by insomnia have it due to crossing several time zones in short periods of time or working the night shift at certain jobs that require you to be in front of a computer screen. This disrupts the body’s internal clock or the circadian rhythm and makes it difficult for humans to fall asleep. Melatonin, a hormone secreted in the brain, can help correct these issues .In the following sections the properties of the compound, benefits, and side
Rasch, Björn, and Jan Born. "About Sleep 's Role in Memory." Physiological Reviews. American Physiological Society, n.d. Web. 06 May 2016.