Nanotechnology and Chemoprevention

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New methods for identification and treatment of cancer cells are continuing to be researched. Colon cancer, one of the leading causes of cancer death in the United States, has been used as the choice for the cancer to identify and treat in certain studies. Through previous experiments, treatments for people with colon cancer have been utilized, but still present issues associated with the treatment is the proper identification of cancer cells and the high toxicity associated with some of the treatments and the effect on the human body. Research into procedures to reduce the identification time of cancer cells and lower the exposure to toxic chemicals in the body led to scientists modifying the delivery of the identification markers and treatments with nanotechnology. Nanoparticles are seen as a viable solution to these problems and its use with identification of cancer cells and treatments were researched and reported to be analyzed for future use. Nanoparticles have been shown to be at times 20nm in length2 and have a higher effectiveness for diffusing encapsulated treatments. Up to 85% effectiveness has been reported in some cases2. The small size of nanoparticles also allows the ability to control what interactions take place by what is encapsulated or what is used to encapsulate the particle. The use of nanoparticles to identify and treat cancer cells were reported by two studies published in Nanoletters and Cancer Prevention Research. The use of nanoparticles as labeling agents in immunoassays, which are tests that use antibodies to detect specific molecules, offers an improvement in sensitivity over traditional enzyme or dye labeling agents. When combined with specific antibodies, it was reported that nanoparticles can ... ... middle of paper ... ... the two compounds required to affect the cancer cells. The information shows that nanoparticles are a viable target delivery system for treatment of cancer cells. Nanoparticles require lower dosage amounts to be a successful treatment option and can be used for targeted delivery. The possibility of those compounds becoming option capable for use in chemoprevention allows for further developments in those compounds to be done. Works Cited 1. Chaudhary, A.; Sutaria, D.; Huang, Y.; Wang, J.; Prabhu, S., Chemoprevention of colon cancer in a rat carcinogenesis model using a novel nanotechnology-based combined treatment system. Cancer prevention research 2011, 4 (10), 1655-64. 2. Maltez-da Costa, M.; de la Escosura-Muniz, A.; Nogues, C.; Barrios, L.; Ibanez, E.; Merkoci, A., Simple monitoring of cancer cells using nanoparticles. Nano letters 2012, 12 (8), 4164-71.

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