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nanotechnoogy is emerging essay
nanotechnoogy is emerging essay
nanotechnoogy is emerging essay
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Regenerative medicine targets the conservation and development of organ function. The modification of tissues is obtained by linking living cells with materials that work as scaffolds to support cell generation. Nanotechnology is the means that feeds the material structure that simulate biological ones and additionally provide a direct delivery system. The functionality of nanotechnology for regenerative medicine is primarily due to its small unit size according to the International System of Units, one nanometer is one-billionth of a meter. The unit size allows for the technological apparatus to navigate the bloodstream and target and fix damage cells in tissues. Tissue engineering uses nanotechnology for tissue regeneration in order to fix damage tissue. In order to succeed tissue engineering utilizes two different methods: in vivo or in vitro regeneration of living tissue. Both methods use Nano scale scaffolds that are loaded with cells in order to regenerate a damage cell in the organ system. The scaffold can also be loaded with different molecules to assist in cell function lik...
At the moment, the main objective for scientists and engineers is to develop surgery into a minimal invasive method and nanote...
Brendan Maher, in his article “How to Build a Heart” discusses doctor’s and engineer’s research and experimentation into the field of regenerative medicine. Maher talks about several different researchers in this fields. One is Doris Taylor, the director of regenerative medicine at the Texas Heart Institute in Houston. Her job includes harvesting organs such as hearts and lungs and re-engineering them starting with the cells. She attempts to bring the back to life in order to be used for people who are on transplant waiting lists. She hopes to be able to make the number of people waiting for transplants diminish with her research but it is a very difficult process. Maher says that researchers have had some successes when it comes to rebuilding organs but only with simples ones such as a bladder. A heart is much more complicated and requires many more cells to do all the functions it needs to. New organs have to be able to do several things in order for them to be used in humans that are still alive. They need to be sterile, able to grow, able to repair themselves, and work. Taylor has led some of the first successful experiments to build rat hearts and is hopeful of a good outcome with tissue rebuilding and engineering. Scientists have been able to make beating heart cells in a petri dish but the main issue now is developing a scaffold for these cells so that they can form in three dimension. Harold Ott, a surgeon from Massachusetts General Hospital and studied under Taylor, has a method that he developed while training. Detergent is pumped into a glass chamber where a heart is suspended and this detergent strips away everything except a layer of collagen, laminins, and other proteins. The hard part according to Ott is making s...
Bone tissue engineering (BTE) plays an important role in treating bone diseases related to osteoporosis and other orthopedic treatments. Although several methods are used in orthopedic surgery, some bone transport methods such as autografting and allografting have a certain number of disadvantages. Both are expensive methods and they can be exposed to infections and diseases. Therefore, in stead of using these potential risky methods, bone tissue engineering process are used to treat in orthopedic treatments. In general, both tissue engineering and bone tissue engineering have major constituents including stem cells, scaffold, bioreactors and growth factors.
Since organs are on short supply throughout the world scientists have taken to trying to create organs in the lab. The field of organ growing is possible thanks to recent advances in stem-cell research and is commonly known as ‘tissue engineering’. Tissue engineering uses the patient’s own cells to build new organs or replace damaged tissues in the patient’s own organs, which is called grafting.3The process works by differentiating pluri-potent stem-cells into the cells that the patient needs. The cells are then allowed to grow and multiply in a nutrient solution. When the cells are in adequate numbers they are sometimes inserted into the patients existing tissue but are most commonly used to grow a new organ or tissue graft.
Our own immune system such as macrophages help in restoring the damage in the heart for example, damage caused by myocardial infarction. Macrophages responsibilities are to clear the infarcted area and activate other cells, such as fibroblasts, endothelial cells and progenitor cells to help the healing process of the blood vessels (Mercola et al. 2011). Tissue regenerative in today’s world uses the stem cell technology to repair, replace and regenerate the cells of the injured organ or tissues. It is a combination of engineering principles and life sciences in order to create something that able to proliferate and regenerate as well as sustaining and improving its functions. This purpose can be achieved by applying functional cells, scaffolds supplementary, stimulate the growth and signal molecules to needed areas. The scaffold delivers as physical support for the cells as well as to function as organizer guiding the cell growth and differentiation (Leor et al. 2005).
Research on stem cells is advancing knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms. This promising area of science is also leading scientists to investigate the possibility of cell-based therapies to treat disease, which is often referred to as regenerative or reparative medicine. There is genuine scientific excitement over the concept of using the body's own cellular building blocks to regenerate damaged or ageing organs. Stem cells are one of the most fascinating areas of biology today. But like ...
Tissue engineering can join the list of medical advances that science-fiction movies beat reality to. This component of regenerative medicine is one of the newest and most intriguing aspects of medicine and is guaranteed to enhance the quality of health care universally.
Since human recognize the material, biomaterials have had initial development. As early as 3500 BC, the ancient Egyptians used sutures made of cotton fiber or horse hair, and in 16th century gold plate was used to repair jaw bone and ceramic materials were used to make dedendum, and so on. With the development of medicine and materials science, especially the success of the research and development of new materials, such as the rapid development of polymer materials in the 1940s provides a great opportunity for the research and application of biomaterials. It could be said that in addition to the brain and most
Today I finished observing all the scaffolds using the SEM Scanning Electron Microscopy (SEM). The end goal for the non-toxic (being tested today) scaffolds is to be use as a temporary bone until the bone repairs. Then the scaffold should degrade until the bone heals properly. Also, the scaffold has to be strong, so it doesn’t break or collapse in the body that was the purpose of the mechanical testing. We have to know every properties of the scaffolds to make the scaffolds are good to be put in the body .Today we will begin testing whether the scaffold is toxic for the cells because the human body is made up of cells. We don’t want to damage the human cells. We will first use animal cells and then we will move on to human cells if the scaffolds
The use of nanobots makes diagnostic procedures fast and more precise. This also leads to patient experience less invasive and more comfortable procedures. Nurses can implement effective interventions and the give better patient care.
The most exceptional trait about nanomedicine is its capability of eliminating cancers and tumors. Cancers and tumors have been a major problem for people worldwide, from families being torn apart, loved ones vanishing, and much more. Both being a complex matter to challenge as for many years it has been a problem and the closest thing that was thought to be the answer was chemotherapy. Many people have been wanting the actual cure and now we might have the answer. In the article “Nanomedicine”(2014), Guizhi Zhu, Lei Mei, and Weihong Tan establishes that:
As the human race is moving towards advancement the number of diseases and disorders are also on increase. To fight against these problems many new health care field have emerged since the past half-decade. Most promising of those fields is the Regenerative medicine. Regenerative medicine is a multidisciplinary field concerned with creating living, functional tissues to repair or replace tissue or organ function lost due to age, disease, or congenital defects (US National Institute of Health). It has been 20 years since the idea of Regenerative Medicine sprung. It all started with the use of tissue engineering to replace body organs or tissues by the ones grown in lab made using the cells from the targeted organs. Since the discovery of stem cells, most research in the field of regenerative medicine has been focused on the manipulating stem cells so they can be used to repair or replace any type of body cell or tissue which before the stem cell discovery was not possible. And so with time the two terms regenerative medicine and stem cells have become quite linked. This field has grabbed a great amount of international attention considering its promising ability to cure many incurable diseases, especially cancers and mental disease, and resulting in better health standards for humans. Basically regenerative medicine is evolution of the modern medicine. DR Pascal J. Goldschmidt, dean of the University of Miami School of Medicine a pioneer institute of research in regenerative medicine, te...
Tissue engineering is often interchanged with “regenerative medicine.” Now, the goal of tissue engineering is to regenerate or heal damaged tissues instead of replacing them, which is what we do today with transplantation.
"Artificial" tissue is grown-up from the patient's personal cells. However, when the harm is so dangerous that it is unbearable to use the patient's own cells, artificial tissue cells are grown. The trouble is in discovery a scaffold that the cells can grow and organize on. The features of the support must be that it is biocompatible; cells can adhere to the support, mechanically durable and recyclable. One successful support is a copolymer of lactic acid and glycolic acid.
The field of regenerative medicine encompasses numerous strategies, including the use of materials and de novo generated cells, as well as various combinations thereof, to take the place of missing tissue, effectively replacing it both structurally and functionally, or to contribute to tissue healing[29]