Chandni Shiwbodh
Molecular Diagnostics
Molecular Diagnostics is defined as tests which identify certain patterns in both RNA and DNA. These tests are able to identify RNA, genes, and protein sequences which play a role in diseases. These sequences may be linked to diseases which include nucleotide polymorphism, deletions, rearrangements, and many more. Molecular Diagnostics is also able to identify and multiply the presence of certain microorganisms and cells. Molecular Diagnostics provides a great amount of clinical information. For example, hereditary disorders to specific drug therapies or hereditary relationships in general. Molecular Diagnostics is also well known for providing qualitative and quantitative results that help in detection,
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One advantage is that many tests can be used during point of care. This results in many simple tests with fast turn around times. Clinicians are also able to get results faster and start treating patients as soon as needed. Another advantage is that Molecular Diagnostic continues to grow and is not limited to only one field of study. Molecular diagnostics can be used in genetics, hematology, infectious diseases, oncology, and pharmacology. Molecular Diagnostics is making huge improvements in Oncology. With these improvements, the public can be scanned for cancer, treat cancer based on subtypes, and monitor the prognosis and therapies of cancer patients. Not only is Molecular Diagnostics making headway in oncology but Microbiology labs prefer to use it over cultures, electron microscopy, and direct immunofluorescence. They would rather use PCR because it has a high sensitivity with a turn around of one day, costs less, used to quantitate microorganisms for treatment and to monitor disease, and also combined with sequencing for antiviral sensitivity and genotyping. One of the greatest advantages of molecular diagnostics is the sensitivity. Most tests detect specific analytes and DNA in small amounts which results in more effective results. Molecular Diagnostics is also an advantage because the biomarker assays and tests are approved in a shorter period of time than …show more content…
Many labs are looking into the great advances of Molecular Diagnostics and relying on these techniques to treat patients’ more effectively and in a shorter period of time. With research and hard work, scientists are working on finding new biomarkers, new risk factors, and new approaches to treat patients’. As Molecular Diagnostics is becoming more frequent in labs, scientists are hoping that the funds will increase to replace lab equipment while trying to keep healthcare
It helps medics to find a direct genetic cause of the patient’s condition and target it with pharmaceutical or other therapies. The technology is used for the identification of DNA sequences that increase risks of current diseases and disorders; with this information carriers can start to make efforts to prevent them before the development of the problem. The video mentioned 200 actionable genes, structures that have direct links with a specific condition. Knowing about their presence, people have a chance to bring in preventive measures like taking anticoagulants in the case of identification of a thrombogenic gene. The technology led to the significant improvement of diagnostics and personalized treatments. It helped to find a rare, life-threatening mutation in case of Beery twins and assign a drug to a girl (Alexis) that returned her to a normal life. In the case of cancer genome sequencing led to the development of genetic drags, which target essential tumor genes and make malign structures to shrink. The video mentioned a product that works with the BRАF protein that induces cells to uncontrolled division; the drug led to the remission in the patient with metastasizing melanoma. Such treatment was effective in the case of cystic fibrosis. In the case of the breast cancer the technology helps to evaluate the aggressiveness of the condition and make a personalized decision about chemotherapy. The video also mentioned the pre-implantation genetic diagnosis – an early-staged technology that prevents the development of inherited disorders in
. DNA can be left or collected from the hair, saliva, blood, mucus, semen, urine, fecal matter, and even the bones. DNA analysis has been the most recent technique employed by the forensic science community to identify a suspect or victim since the use of fingerprinting. Moreover, since the introduction of this new technique it has been a large number of individuals released or convicted of crimes based on DNA left at the crime sceneDNA is the abbreviation for deoxyribonucleic acid. DNA is the genetic material found in cells of all living organisms. Human beings contain approximately one trillion cells (Aronson 9). DNA is a long strand in the shape of a double helix made up of small building blocks (Riley). There are four types of building
All spring and summer the townsfolk spoke about the three bodies that had been found, mangled and slashed. Now, had the three men headed the warning and stayed away from the old man’s house they would still be alive. Instead they were tempted by the greed in their hearts for the money the terrible old man was said to have possession of. This drove them to enter through his gate and knock on the door. They believed that because he was an old man, he would be feeble and week, making him an easy target for
Advantages of genetic testing may be helpful in determining whether or not you have a disease or are proba...
By using identified gene mutations that are known to cause diseases, asymptomatic individuals are able to discover if they are at risk for specific genetic conditions; this is known as genetic testing. Unfortunately, genetic testing can vary in its predictive ability. For example, Huntington disease, Duchenne Muscular Dystrophy, Fragile X syndrome and multiple endocrine neoplasia type 2 are conditions that can be determined by genetic testing (Samen, 1996). In contrast, for multifaceted diseases like Alzheimer’s, breast and ovarian cancer and colorectal cancer, predisposition can be determined with genetic testing. However, an absolute diagnosis of those diseases cannot be made (Heshka et al., 2008).
Due to the human genome project and other genetic research, tests for mutation which cause diseases have been developed. The list of these illnesses include several types of cancer. Doctors have estimated that as many as 3,000 diseases are due to mutations in the genome. These diseases include several types of colon cancer in which three different genetic tests have been already developed. Debates have arisen on whether these tests should be used regularly or not. Questions including the patients= rights of privacy and the possibility of loss of health or life insurance have been argued over in both the media and political arena.
Another reason the testing is used is because it develops solutions to medical problems. More than half the animals that have been tested on have succeeded in finding a cure for the human race.
When it comes to genetic diseases and conditions, testing can be very helpful and serve a good purpose. People with diseases that are inheritable to their children are encouraged to be tested. For example, in the article about Jewish testing, it says
Deoxyribonucleic acid (DNA) is an acclaimed extraordinary discovery that has contributed great benefits in several fields throughout the world. DNA evidence is accounted for in the majority of cases presented in the criminal justice system. It is known as our very own unique genetic fingerprint; “a chromosome molecule which carries genetic coding unique to each person with the only exception of identical twins (that is why it is also called 'DNA fingerprinting ')” (Duhaime, n.d.). DNA is found in the nuclei of cells of nearly all living things.
Edgar Allen Poe's "The Tell Tale Heart" is a short story about how a murderer's conscience overtakes him and whether the narrator is insane or if he suffers from over acuteness of the senses. Poe suggests the narrator is insane by the narrator's claims of sanity, the narrator's actions bring out the narrative irony of the story, and the narrator is insane according to the definition of insanity as it applies to "The Tell Tale Heart".
In today’s world, people are learning a great deal in the rapidly growing and developing fields of science and technology. Almost each day, an individual can see or hear about new discoveries and advances in these fields of study. One science that is rapidly progressing is genetic testing; a valuable science that promotes prevention efforts for genetically susceptible people and provides new strategies for disease management. Unnaturally, and morally wrong, genetic testing is a controversial science that manipulates human ethics. Although genetic testing has enormous advantages, the uncertainties of genetic testing will depreciate our quality of life, and thereby result in psychological burden, discrimination, and abortion.
In the film “ A Beautiful Mind” John Nash experiences a few different positive symptoms. The first of these positive symptoms are seen through the hallucinations John has of having a room -mate while at Princeton. This room- mate continues to stay “in contact” with John through out his adult life and later this room- mate’s niece enters Johns mind as another coinciding hallucination. Nash’s other hallucination is Ed Harris, who plays a government agent that seeks out Nash’s intelligence in the field of code- breaking.
Today, there are more advanced lab tests to help doctors classify ALL so they no longer have to rely on just the cell’s characteristics. These new lab tests aid in the grouping of ALL based on the type of lymphocyte the leukemia stems from (B cell or T cell) and how mature the cancer cells are (American Cancer Society, 2013)54.... ... middle of paper ... ... Diseases & Conditions - Medscape Reference.
Westgard, J. O. (2013). Perspectives on Quality Control, Risk Management, and Analytical Quality Management. Clinics in Laboratory Medicine, 33(1), 1-14.
Most diseases are caused by a type of genetic component. Many of the diseases that have been caused by gene mutations are undiagnosed. These remain undiagnosed because the disease is so rare that the doctor does not know how to diagnose the patient. Many sy...